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MPH-220 , CAS No.2649776-79-2

COA

Cas Number: 2649776-79-2
Molecular Weight: 383.46

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Item Number

M647601

Grouped product items
SKU	Size	Availability	Price	Qty
M647601-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$425.90
M647601-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$675.90

View related series

Cytoskeleton (498) Myosin (30)

Basic Description

Biochemical and Physiological Mechanisms	MPH-220 is a selective and orally active inhibitor of skeletal muscle myosin-2 . MPH-220 enables muscle relaxation. MPH-220 is anti-spastic agent that can be used in the research of spasticity and muscle stiffness.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	MPH-220 is a selective and orally active inhibitor of skeletal muscle myosin-2. MPH-220 enables muscle relaxation. MPH-220 is anti-spastic agent that can be used in the research of spasticity and muscle stiffness. In Vitro MPH-220 (0-50 µM) inhibits Actin-activated ATPase activity in human muscle myosin samples. MCE has not independently confirmed the accuracy of these methods. They are for reference only. In Vivo MPH-220 (25-30 mg/kg, i.p. or oral gavage) reduces skeletal muscle force without cardiovascular effects in anesthetized rats . MPH-220 (15 mg/kg, oral administration) improves gait functions in rats with brain injury . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Anesthetized rats Dosage: 25-30 mg/kg Administration: Intraperitoneal injection (i.p.) or oral gavage Result: Reduced skeletal muscle force. Observed MPH-220 distribution in rat tissues in a time-dependent manner and a dose-dependent, few-fold accumulation in skeletal muscle.

Names and Identifiers

Smiles	O[C@@]12C(N(C3=CC=C(N4CCOCC4)C=C3)CC2)=NC5=C(C=C(S5)C)C1=O
Molecular Weight	383.46

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