This is a demo store. No orders will be fulfilled.

Morpholine - analytical standard,≥99.5%(GC), high purity , CAS No.110-91-8

In stock
Item Number
M109060
Grouped product items
SKU Size
Availability
Price Qty
M109060-5ml
5ml
5
$91.90

Basic Description

Synonyms MORPHOLINE | 110-91-8 | 1-Oxa-4-azacyclohexane | Diethylene oximide | Tetrahydro-1,4-oxazine | Diethylenimide oxide | Diethyleneimide oxide | Diethylene imidoxide | Drewamine | Tetrahydro-2H-1,4-oxazine | Tetrahydro-p-oxazine | p-Isoxazine, tetrahydro- | morpholin | Tetrahydro-1,4
Specifications & Purity analytical standard, ≥99.5%(GC)
Storage Temp Room temperature
Shipped In Normal
Grade analytical standard

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Organoheterocyclic compounds
Class Oxazinanes
Subclass Morpholines
Intermediate Tree Nodes Not available
Direct Parent Morpholines
Alternative Parents Oxacyclic compounds  Dialkylamines  Dialkyl ethers  Azacyclic compounds  Organopnictogen compounds  Hydrocarbon derivatives  
Molecular Framework Aliphatic heteromonocyclic compounds
Substituents Morpholine - Oxacycle - Azacycle - Secondary amine - Ether - Secondary aliphatic amine - Dialkyl ether - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Amine - Aliphatic heteromonocyclic compound
Description This compound belongs to the class of organic compounds known as morpholines. These are organic compounds containing a morpholine moiety, which consists of a six-member aliphatic saturated ring with the formula C4H9NO, where the oxygen and nitrogen atoms lie at positions 1 and 4, respectively.
External Descriptors morpholines - saturated organic heteromonocyclic parent

Associated Targets(Human)

CYP1B1 Tchem Cytochrome P450 1B1 (1148 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CYP1A1 Tchem Cytochrome P450 1A1 (1169 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

IUPAC Name morpholine
INCHI InChI=1S/C4H9NO/c1-3-6-4-2-5-1/h5H,1-4H2
InChIKey YNAVUWVOSKDBBP-UHFFFAOYSA-N
Smiles C1COCCN1
Isomeric SMILES C1COCCN1
WGK Germany 1
RTECS QD6475000
UN Number 2054
Packing Group I
Molecular Weight 87.12
Beilstein 102549
Reaxy-Rn 102549
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=102549&ln=

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
G2318916 Certificate of Analysis Jul 28, 2023 M109060
G2318913 Certificate of Analysis Jul 28, 2023 M109060
I2018087 Certificate of Analysis Jul 18, 2022 M109060

Chemical and Physical Properties

Solubility It is miscible with water and can be miscible with most organic solvents.
Sensitivity Hygroscopic
Refractive Index 1.4548
Flash Point(°F) 87.8 °F
Flash Point(°C) 35℃
Boil Point(°C) 128.3°C
Melt Point(°C) -4.76°C
Molecular Weight 87.120 g/mol
XLogP3 -0.900
Hydrogen Bond Donor Count 1
Hydrogen Bond Acceptor Count 2
Rotatable Bond Count 0
Exact Mass 87.0684 Da
Monoisotopic Mass 87.0684 Da
Topological Polar Surface Area 21.300 Ų
Heavy Atom Count 6
Formal Charge 0
Complexity 34.500
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 1

Citations of This Product

1. Jun-Tao Shi, Xian-Hui Chen, Yuan-Yuan Peng, Gui-Ping Wang, Guang-Yan Du, Quan Li.  (2023)  Tunable Fluorescence and Morphology of Aggregates Built from a Mechanically Bonded Amphiphilic Bistable [2]Rotaxane.  CHEMISTRY-A EUROPEAN JOURNAL,  29  (59): (e202302132). 
2. Ke Wang, Liru An, Ganghui Lu, Jialu Zhang, Zilong Wang, Meiyu Si, Guiyan Liu, Yongfei Zeng.  (2023)  Effect of heterocyclic substituents on the thermo/pH/CO2-responsiveness of multistimuli-responsive homopolymers.  POLYMER,  280  (126039). 
3. Qiong Yao, Shouwu Yu.  (2023)  Preparation and characterisation of a triazine structure charring agent and its application in polypropylene.  MATERIALS RESEARCH INNOVATIONS,     
4. Siyuan Li, Xianrong Yu, Linlin Zeng, Yuhan Xu, Xiaolan Zhao, Wei Tang, Xinrui Duan.  (2022)  A Sensitive Fluorescent Probe with Large Stokes Shift for Real-Time Tracking Lysosomal pH Changes in Live Cells.  ChemistrySelect,  (42): (e202202620). 
5. Caiyun Lin, Yuying Li, Weishan Tang, Shufeng Zhou, Xiaoping Rao.  (2021)  Facile Construction of Bio-Based Supramolecular Hydrogels from Dehydroabietic Acid with a Tricyclic Hydrophenanthrene Skeleton and Stabilized Gel Emulsions.  MOLECULES,  26  (21): (6526). 
6. Yingnan Liu, Yaqing Xiao, Minghui Shang, Yuting Zhuang, Li Wang.  (2022)  Smart fluorescent tag based on amine response for non-contact and visual monitoring of seafood freshness.  CHEMICAL ENGINEERING JOURNAL,  428  (132647). 
7. Jun Mou, Xingqi Fan, Fei Liu, Xiaodan Wang, Tianxiang Zhao, Peng Chen, Ziwei Li, Chunliang Yang, Jianxin Cao.  (2021)  CO2 hydrogenation to lower olefins over Mn2O3-ZnO/SAPO-34 tandem catalysts.  CHEMICAL ENGINEERING JOURNAL,  421  (129978). 
8. Faming Wang, Pengfei Ren, Katrien V. Bernaerts, Yifu Fu, Wanjun Hu, Naizhen Zhou, Tianzhu Zhang.  (2020)  Thermoresponsive Poly(2-propyl-2-oxazoline) Surfaces of Glass for Nonenzymatic Cell Harvesting.  ACS Applied Bio Materials,  (8): (5428–5437). 
9. Shao-Lu Li, Pengfei Wu, Juntao Wang, Jing Wang, Yunxia Hu.  (2020)  Fabrication of high performance polyamide reverse osmosis membrane from monomer 4-morpholino-m-phenylenediamine and tailoring with zwitterions.  DESALINATION,  473  (114169). 
10. Min Shi, Yanhong Li, Hongtao Cui.  (2019)  Building homogeneous nanostructure in Ni(OH)2/MWCNTs composite by electrostatic attraction.  Micro & Nano Letters,  14  (11): (1151-1156). 
11. Song Wen-tao, Hu Yong-jun, Jin Shan, Li Yu-jian.  (2019)  Dissociative photoionization of heterocyclic molecule-morpholine under VUV synchrotron radiation.  CHINESE JOURNAL OF CHEMICAL PHYSICS,  32  (2): (259-266). 
12. Yanhong Li, Jing Li, Meiri Wang, Yuanyuan Liu, Hongtao Cui.  (2019)  High rate performance and stabilized cycle life of Co2+-doped nickel sulfide nanosheets synthesized by a scalable method of solid-state reaction.  CHEMICAL ENGINEERING JOURNAL,  366  (33). 
13. Xinxin Li, Qingshan Zhao, Xiang Feng, Lei Pan, Zhuangzhuang Wu, Xiaocui Wu, Tianwen Ma, Jialiang Liu, Yuanyuan Pan, Yan Song, Mingbo Wu.  (2019)  Pyridinic Nitrogen-Doped Graphene Nanoshells Boost the Catalytic Efficiency of Palladium Nanoparticles for the N-Allylation Reaction.  ChemSusChem,  12  (4): (858-865). 
14. Wang Li, Li Jing, Wang Meiri, Liu Yuanyuan, Cui Hongtao.  (2019)  In situ synthesis of two-dimensional Co2+-doped β-Ni(OH)2 using nickel complex as template for application in supercapacitors.  JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY,  89  (2): (492-499). 
15. Wu Hong, Wang Xianshu, Liu Fei, Cao Jianxin.  (2019)  Facile in situ hydrothermal crystallization synthesis of SAPO-34/ZSM-5 composite catalyst for methanol to olefin reaction.  JOURNAL OF POROUS MATERIALS,  26  (3): (793-802). 
16. Mengsi Cao, Pingping Zhang, Yanru Feng, Huayin Zhang, Huaijiao Zhu, Kaoqi Lian, Weijun Kang.  (2018)  Development of a Method for Rapid Determination of Morpholine in Juices and Drugs by Gas Chromatography-Mass Spectrometry.  Journal of Analytical Methods in Chemistry,  2018  (9670481). 
17. Huaqi Zhan, Yongjun Hu, Pengchao Wang, Jiaxin Chen.  (2017)  Molecular structures of gas-phase neutral morpholine and its monohydrated complexes: experimental and theoretical approaches.  RSC Advances,  (11): (6179-6186). 
18. Ma Wenle, Feng Yongmei, Wang Li, Xue Junying, Cui Hongtao.  (2016)  Tailoring the size and electrochemical performance of Mn3O4 nanoparticles by controlling the precipitation process.  JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY,  80  (2): (326-332). 
19. Yapeng Hu, Xiangmei Wang, Juan Li.  (2016)  Regulating Effect of Exfoliated Clay on Intumescent Char Structure and Flame Retardancy of Polypropylene Composites.  INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH,  55  (20): (5892–5901). 
20. Wenle Ma, Li Wang, Junying Xue, Hongtao Cui.  (2016)  Ultra-large scale synthesis of Co–Ni layered double hydroxides monolayer nanosheets by a solvent-free bottom-up strategy.  JOURNAL OF ALLOYS AND COMPOUNDS,  662  (315). 
21. Zhong Zheng, Yihu Song, Huilong Xu, Qiang Zheng.  (2015)  Thickening of the Immobilized Polymer Layer Using Trace Amount of Amine and Its Role in Promoting Gelation of Colloidal Nanocomposites.  MACROMOLECULES,  48  (24): (9015–9023). 
22. Ma Wenle, Xue Junying, Cui Hongtao.  (2016)  New insight on nanostructure assembling of high-performance electrode materials: synthesis of surface-modified hexagonal β-Ni(OH)2 nanosheets as an example.  IONICS,  22  (4): (573-579). 
23. Hongtao Cui, Junying Xue, Wanzhong Ren, Minmin Wang.  (2015)  Ultra-large scale synthesis of high electrochemical performance SnO2 quantum dots within 5 min at room temperature following a growth self-termination mechanism.  JOURNAL OF ALLOYS AND COMPOUNDS,  645  (11). 
24. Hongtao Cui, Junyin Xue, Minmin Wang.  (2015)  Synthesis of high electrochemical performance Ni(OH)2 nanosheets through a solvent-free reaction for application in supercapacitor.  ADVANCED POWDER TECHNOLOGY,  26  (434). 
25. Yan Liu, Zhenhu Cao, Yan Zhang, Zhengping Fang.  (2015)  Synthesis of zinc N-morpholinomethylphosphonic acid and its application in high density polyethylene.  FIRE SAFETY JOURNAL,  71  (1). 
26. Ming-Hui He, Mei-Lin Su, Zhao-Hui Yu, Guang-Xue Chen, Zhao-Hua Zeng, Jian-Wen Yang.  (2015)  Benzoylformamides as new photocaged bases for photo-latent anion polymerization.  CHINESE CHEMICAL LETTERS,  26  (21). 
27. Minghui He, Shun Jiang, Ruixin Xu, Jianwen Yang, Zhaohua Zeng, Guangxue Chen.  (2014)  Domino free radical photopolymerization based on phototriggered base proliferation reaction and redox initiation.  JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY,  52  (11): (1560-1569). 
28. Yan Liu, Zhenhu Cao, Yan Zhang, Zhengping Fang.  (2013)  Synthesis of Cerium N-Morpholinomethylphosphonic Acid and Its Flame Retardant Application in High Density Polyethylene.  INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH,  52  (15): (5334–5340). 
29. Min Xie, Guichi Zhu, Yongjun Hu, Huaimin Gu.  (2011)  Conformations of Morpholine in Liquid and Adsorbed on Gold Nanoparticles Explored by Raman Spectroscopy and Theoretical Calculations.  Journal of Physical Chemistry C,  115  (42): (20596–20602). 
30. Yan Yan,Pengchong Wang,Ruiying Li,Ying Sun,Rui Zhang,Chuanchuan Huo,Jianfeng Xing,Yalin Dong.  (2019-03-13)  Synthesis of budesonide conjugates and their anti-inflammatory effects: a preliminary study..  Drug design, development and therapy,  13  (681-694). 
31. Weidong Nie, Yuanyuan Liu, Jing Li, Meiri Wang, Kaihua Liu, Hongtao Cui.  (2024)  A new carbon modification strategy aimed to fully address the issues of NiO as an electrode material for supercapacitors.  JOURNAL OF ALLOYS AND COMPOUNDS,  984  (174027). 
32. Yiwei Sun, Xiaoli Wei, Wei Zhang, Zhen Wang, Jianhai Jiang, Fangcao Liu, Bing Liu, Wenfeng Han.  (2024)  Carbon-Interacted AlF3 Clusters as Robust Catalyst for Dehydrofluorination Reaction with Enhanced Undercoordination and Stability.  ACS Catalysis,  14  (4): (2358-2368). 
33. Zhonggeng Wang, Luzhu Fang, Sensen Ma, Xuejing Zheng, Jianfeng Wang, Yanyu Yang, Wanjie Wang, Yanxia Cao.  (2025)  Dispersibility study of eight types of nanofibrillated cellulose and their Hansen solubility parameters.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  308  (142498). 
34. Chenyang Nie, Yuanhao Li, Xiaona Liu, Nana Yan, Chao Ma, Jiahui Zhu, Linlin Hao, Peng Guo, Zhongmin Liu.  (2025)  DNL-17: A Small-Pore Aluminophosphate in ABC-6 Family with 24 Stacking Layers Unraveled by Three-Dimensional Electron Diffraction.  Journal of the American Chemical Society,  147  (6): (5440-5448). 
35. Xiuzhen Zhao, Yin Cai, Jishi Chen, Aiping Fu, Fang Ge.  (2024)  Group transfer polymerization of polar conjugated monomers using pinacolborane and thiourea anions.  JOURNAL OF POLYMER SCIENCE,     
36. Jubao Gao, Xinyue Yang, Zichun Xing, Xueyi Song, Yixuan Liu, Zhichao Wang, Gaofeng Deng, Xinglei Zhao.  (2024)  Physicochemical and thermodynamic properties of binary amine-based deep eutectic solvents for carbon capture.  JOURNAL OF MOLECULAR LIQUIDS,  399  (124346). 

Solution Calculators

Reviews

Customer Reviews

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.