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ML 315 hydrochloride - 98%, high purity , CAS No.1440251-53-5

COA

Grade & Purity:

≥98%

Cas Number: 1440251-53-5
Molecular Weight: 410.68
PubChem CID: 127021037

In stock

Item Number

M288578

Grouped product items
SKU	Size	Availability	Price
M288578-5mg	5mg	3	$239.90
M288578-10mg	10mg	3	$369.90
M288578-25mg	25mg	2	$739.90
M288578-50mg	50mg	1	$1,169.90
M288578-100mg	100mg	1	$1,879.90

Inhibitor of Clk and DYRK kinases

View related series

Cell Cycle (2830) CLK (Cdc2-like Kinase) Inhibitors (1) Non-receptor Tyrosine Kinase (643)

Basic Description

Synonyms	5-(1,3-Benzodioxol-5-yl)-N-[(3,5-dichlorophenyl)methyl]-4-pyrimidinamine hydrochloride
Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	Inhibitor of cdc2-like kinases (Clk) and DYRK kinases (IC50values are 68, 68 and 231 nM for Clk1, Clk4 and Clk2, respectively, and 282 and 1156 nM for Dyrk1A and Dyrk1B). Shows 20-fold selectivity for Clk4 over Dyrk1A. Stable in both mouse and human plasm
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.

Names and Identifiers

IUPAC Name	5-(1,3-benzodioxol-5-yl)-N-[(3,5-dichlorophenyl)methyl]pyrimidin-4-amine;hydrochloride
INCHI	InChI=1S/C18H13Cl2N3O2.ClH/c19-13-3-11(4-14(20)6-13)7-22-18-15(8-21-9-23-18)12-1-2-16-17(5-12)25-10-24-16;/h1-6,8-9H,7,10H2,(H,21,22,23);1H
InChIKey	MNCDEAAKKQCKSX-UHFFFAOYSA-N
Smiles	C1OC2=C(O1)C=C(C=C2)C3=CN=CN=C3NCC4=CC(=CC(=C4)Cl)Cl.Cl
PubChem CID	127021037
Molecular Weight	410.68

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

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10 results found

Lot Number	Certificate Type	Date	Item
F2414161	Certificate of Analysis	Feb 28, 2024	M288578
F2414162	Certificate of Analysis	Feb 28, 2024	M288578
F2414163	Certificate of Analysis	Feb 28, 2024	M288578
F2414164	Certificate of Analysis	Feb 28, 2024	M288578
F2414177	Certificate of Analysis	Feb 28, 2024	M288578
F2414182	Certificate of Analysis	Feb 28, 2024	M288578
F2414183	Certificate of Analysis	Feb 28, 2024	M288578
F2414184	Certificate of Analysis	Feb 28, 2024	M288578
F2414185	Certificate of Analysis	Feb 28, 2024	M288578
F2414211	Certificate of Analysis	Feb 28, 2024	M288578

Chemical and Physical Properties

Solubility	Solvent:DMSO, Max Conc. mg/mL: 37.42, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 18.71, Max Conc. mM: 50

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