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ML 218 hydrochloride - ≥99%(HPLC), high purity , CAS No.2319922-08-0

COA

Grade & Purity:

≥99%(HPLC)

Cas Number: 2319922-08-0
Molecular Weight: 405.79
PubChem CID: 90488946

In stock

Item Number

M288331

Grouped product items
SKU	Size	Availability	Price	Qty
M288331-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$215.90
M288331-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$904.90

CaV3.x blocker

View related series

Ion channel (2197)

Basic Description

Synonyms	3,5-Dichloro-N-[[(1α,5α,6-exo,6α)-3-(3,3-dimethylbutyl)-3-azabicyclo[3.1.0]hex-6-yl]methyl]-benzamide hydrochloride
Specifications & Purity	≥99%(HPLC)
Biochemical and Physiological Mechanisms	Selective inhibitor of T-type calcium channels (IC50values are 270 and 310 nM for Cav3.3 and Cav3.2 respectively in a patch EP assay). Decreases burst activity in STN neurons; reduces cataleptic behaviour in anin vivorat model of Parkinson's disease. Disp
Storage Temp	Store at 2-8°C
Shipped In	Wet ice This product requires cold chain shipping. Ground and other economy services are not available.

Names and Identifiers

IUPAC Name	3,5-dichloro-N-[[(1S,5R)-3-(3,3-dimethylbutyl)-3-azabicyclo[3.1.0]hexan-6-yl]methyl]benzamide;hydrochloride
INCHI	InChI=1S/C19H26Cl2N2O.ClH/c1-19(2,3)4-5-23-10-16-15(17(16)11-23)9-22-18(24)12-6-13(20)8-14(21)7-12;/h6-8,15-17H,4-5,9-11H2,1-3H3,(H,22,24);1H/t15?,16-,17+;
InChIKey	IDCVEUISZZKMKJ-ZXVFAPHLSA-N
Smiles	CC(C)(C)CCN1CC2C(C1)C2CNC(=O)C3=CC(=CC(=C3)Cl)Cl.Cl
Isomeric SMILES	CC(C)(C)CCN1C[C@@H]2[C@H](C1)C2CNC(=O)C3=CC(=CC(=C3)Cl)Cl.Cl
PubChem CID	90488946
Molecular Weight	405.79

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Chemical and Physical Properties

Solubility	Solvent:DMSO, Max Conc. mg/mL: 36.93, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 36.93, Max Conc. mM: 100

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