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ML 2-14 - 99%, high purity , CAS No.M658700

    Grade & Purity:
  • ≥99%
  • Molecular Weight:  847.65
In stock
Item Number
M658700
Grouped product items
SKU Size
Availability
Price Qty
M658700-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$260.90
M658700-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$780.90
M658700-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,250.90

Basic Description

Specifications & Purity ≥99%
Storage Temp Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Product Description

ML 2-14 is a PROTAC for degrading BRD4 , with C4 alkyl linker. ML 2-14 exerts degradation of BRD4 in 231MFP breast cancer cells.

Appearance:Solid

In Vitro:ML 2-14 with C4 alkyl linker showes robust degradation of BRD4 in 231MFP breast cancer cells, with DC 50 values of 36 and 14 nM for the long and short isoforms of BRD4, respectively. MCE has not independently confirmed the accuracy of these methods.

Biological Activity:ML 2-14 is a PROTAC for degrading BRD4 , with C4 alkyl linker. ML 2-14 exerts degradation of BRD4 in 231MFP breast cancer cells.

Names and Identifiers

Smiles ClC1=CC=C(C=C1)C2=N[C@@H](CC(NCCCCOC3=CC=C(C4CC(C5=CC=C(Br)C=C5)=NN4C(CCl)=O)C=C3)=O)C6=NN=C(C)N6C7=C2C(C)=C(C)S7
Molecular Weight 847.65

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Chemical and Physical Properties

Solubility DMSO : 100 mg/mL (117.97 mM; Need ultrasonic)

Solution Calculators

Reviews

Customer Reviews

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