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ML 179 - 98%，98atom%D, high purity , CAS No.1883548-87-5

COA

Grade & Purity:

≥98 atom% D,≥98%

Cas Number: 1883548-87-5
Molecular Weight: 422.44
PubChem CID: 75089674
PubChem SID: 488202353

In stock

Item Number

M288627

Grouped product items
SKU	Size	Availability	Price
M288627-5mg	5mg	3	$132.90
M288627-10mg	10mg	3	$204.90
M288627-25mg	25mg	2	$459.90
M288627-50mg	50mg	1	$855.90
M288627-250mg	250mg	1	$3,851.90

Selective liver receptor homolog 1 (LRH1) inverse agonist

Basic Description

Synonyms	2,5-Furandione-3,4-d2 \| 3-Cyclohexyl-6-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]-1H-pyrimidine-2,4-dione
Specifications & Purity	≥98 atom% D,≥98%
Biochemical and Physiological Mechanisms	Selective liver receptor homolog 1 (LRH1, NR5A2) inverse agonist (IC50= 320 nM and maximum efficacy of 64% repression). Exhibits >31-fold selectivity over SF1.
Storage Temp	Protected from light,Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	Product Describtion: ML179 (SR-1309) is a inverse LRH1 (Liver receptor homologue-1) agonist with IC50 of 320 nM. ML179 shows anti-proliferation activity in MDA-MB-231 cells. ML179 has the potential for the research of ER-negative breast cancer .

Names and Identifiers

Pubchem Sid	488202353
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488202353
IUPAC Name	3-cyclohexyl-6-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]-1,3-diazinane-2,4-dione
INCHI	InChI=1S/C21H27F3N4O2/c22-21(23,24)15-5-4-8-17(13-15)26-9-11-27(12-10-26)18-14-19(29)28(20(30)25-18)16-6-2-1-3-7-16/h4-5,8,13,16,18H,1-3,6-7,9-12,14H2,(H,25,30)
InChIKey	KTWKLBPBUXCXRG-UHFFFAOYSA-N
Smiles	C1CCC(CC1)N2C(=O)CC(NC2=O)N3CCN(CC3)C4=CC=CC(=C4)C(F)(F)F
Isomeric SMILES	C1CCC(CC1)N2C(=O)CC(NC2=O)N3CCN(CC3)C4=CC=CC(=C4)C(F)(F)F
PubChem CID	75089674
Molecular Weight	422.44

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

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10 results found

Lot Number	Certificate Type	Date	Item
E23151019	Certificate of Analysis	Mar 27, 2023	M288627
E2315324	Certificate of Analysis	Mar 27, 2023	M288627
E2315337	Certificate of Analysis	Mar 27, 2023	M288627
E2315344	Certificate of Analysis	Mar 27, 2023	M288627
E2315313	Certificate of Analysis	Mar 27, 2023	M288627
E2315300	Certificate of Analysis	Mar 27, 2023	M288627
E2315292	Certificate of Analysis	Mar 27, 2023	M288627
E2315314	Certificate of Analysis	Mar 27, 2023	M288627
E2315301	Certificate of Analysis	Mar 27, 2023	M288627
E2315291	Certificate of Analysis	Mar 27, 2023	M288627

Chemical and Physical Properties

Solubility	Solvent:DMSO, Max Conc. mg/mL: 21.12, Max Conc. mM: 50
Sensitivity	Moisture sensitive； Light sensitive

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