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Milameline hydrochloride - ≥99%(HPLC), high purity , CAS No.139886-04-7

COA

Grade & Purity:

≥99%(HPLC)

Cas Number: 139886-04-7
Molecular Weight: 190.67
PubChem CID: 9571001

In stock

Item Number

M288672

Grouped product items
SKU	Size	Availability	Price	Qty
M288672-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$154.90
M288672-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$648.90

Muscarinic receptor agonist

View related series

Class A GPCR (4138) GPCR/G Protein (3172) mAChR (182) Neuronal Signaling (3320)

Basic Description

Synonyms	RU 35926 \| 1,2,5,6-Tetrahydro-1-methylnicotinaldehyde (E)-O-methyloxime monohydrochloride \| MILAMELINE HYDROCHLORIDE \| J-007328 \| Milameline HCl \| Milameline hydrochloride (USAN) \| PD 129409 \| W867E71LPD \| Miramelin \| CI 979; Milameline hydrochloride; PD
Specifications & Purity	≥99%(HPLC)
Biochemical and Physiological Mechanisms	Muscarinic receptor agonist that displays roughly equal affinity at all receptor subtypes (Kivalues are 2.3, 2.4, 3.6, 3.8 and 4.3μM for hM1, hM2, hM3, hM4and hM5receptors respectively). Cognitive enhancer; reverses spatial memory deficits in rats.
Storage Temp	Store at -20°C,Desiccated
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
  - Class Pyridines and derivatives
    - Subclass Hydropyridines

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
Class	Pyridines and derivatives
Subclass	Hydropyridines
Intermediate Tree Nodes	Not available
Direct Parent	Hydropyridines
Alternative Parents	Trialkylamines Oxime ethers Azacyclic compounds Organooxygen compounds Hydrochlorides Hydrocarbon derivatives
Molecular Framework	Aliphatic heteromonocyclic compounds
Substituents	Hydropyridine - Tertiary aliphatic amine - Tertiary amine - Oxime ether - Azacycle - Organic nitrogen compound - Organic oxygen compound - Hydrocarbon derivative - Hydrochloride - Organooxygen compound - Organonitrogen compound - Amine - Aliphatic heteromonocyclic compound
Description	This compound belongs to the class of organic compounds known as hydropyridines. These are compounds containing a hydrogenated pyridine ring (i.e. containing less than the maximum number of double bonds.).
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Names and Identifiers

IUPAC Name	(E)-N-methoxy-1-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)methanimine;hydrochloride
INCHI	InChI=1S/C8H14N2O.ClH/c1-10-5-3-4-8(7-10)6-9-11-2;/h4,6H,3,5,7H2,1-2H3;1H/b9-6+;
InChIKey	WEBMRZODPLSRKR-MLBSPLJJSA-N
Smiles	CN1CCC=C(C1)C=NOC.Cl
Isomeric SMILES	CN1CCC=C(C1)/C=N/OC.Cl
Alternate CAS	139886-04-7
Molecular Weight	190.67
Reaxy-Rn	14843631
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=14843631&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Chemical and Physical Properties

Solubility	Solvent:water, Max Conc. mg/mL: 19.07, Max Conc. mM: 100
Molecular Weight	190.670 g/mol
XLogP3
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	2
Exact Mass	190.087 Da
Monoisotopic Mass	190.087 Da
Topological Polar Surface Area	24.800 Å²
Heavy Atom Count	12
Formal Charge	0
Complexity	175.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	1
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	1
Covalently-Bonded Unit Count	2

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