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Microcystin-WR - 10ug/ml in methanol, high purity , CAS No.138234-58-9

COA

Grade & Purity:

10ug/ml in methanol

Cas Number: 138234-58-9
Molecular Weight: 1068.22
PubChem CID: 101619976

In stock

Item Number

M299662

Grouped product items
SKU	Size	Availability	Price	Qty
M299662-1ml	1ml	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$3,434.90

Basic Description

Synonyms	Microcystin WR \| Microcystin-WR \| 138234-58-9 \| 3-L-Tryptophan-5-L-argininecyanoginosin La \| (5R,8S,11R,12S,15S,18S,19S,22R)-15-[3-(diaminomethylideneamino)propyl]-8-(1H-indol-3-ylmethyl)-18-[(1E,3E,5S,6S)-6-methoxy-3,5-dimethyl-7-phenylhepta-1,3-dienyl]-1,5,12,1
Specifications & Purity	10ug/ml in methanol
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	Product introduction： Microcystins (MCs) are hepatotoxic cyclic heptapeptides, produced by various cyanobacterial species. MC’s cause adverse effects on freshwater systems with algae blooms. Microcystin WR contains tryptophane (W) in position 2 and arginine (R) in position 4.Microcystins are potent inhibitors of protein phosphatase types 1 and 2A (IC50 value of MC-WR for inhibiting PP2A = 0.18 nM). No effects on protein kinases are known. MCs are known to be hepatic tumor promoters in experimental animal models.

Names and Identifiers

IUPAC Name	(5R,8S,11R,12S,15S,18S,19S,22R)-15-[3-(diaminomethylideneamino)propyl]-8-(1H-indol-3-ylmethyl)-18-[(1E,3E,5S,6S)-6-methoxy-3,5-dimethyl-7-phenylhepta-1,3-dienyl]-1,5,12,19-tetramethyl-2-methylidene-3,6,9,13,16,20,25-heptaoxo-1,4,7,10,14,17,21-heptazacyclopentacosane-11,22-dicarboxylic acid
INCHI	InChI=1S/C54H73N11O12/c1-29(25-30(2)43(77-8)26-35-15-10-9-11-16-35)20-21-38-31(3)46(67)62-41(52(73)74)22-23-44(66)65(7)34(6)49(70)59-33(5)48(69)63-42(27-36-28-58-39-18-13-12-17-37(36)39)51(72)64-45(53(75)76)32(4)47(68)61-40(50(71)60-38)19-14-24-57-54(55)56/h9-13,15-18,20-21,25,28,30-33,38,40-43,45,58H,6,14,19,22-24,26-27H2,1-5,7-8H3,(H,59,70)(H,60,71)(H,61,68)(H,62,67)(H,63,69)(H,64,72)(H,73,74)(H,75,76)(H4,55,56,57)/b21-20+,29-25+/t30-,31-,32-,33+,38-,40-,41+,42-,43-,45+/m0/s1
InChIKey	UGNOHFGJSOFQHC-ZISXDMAXSA-N
Smiles	CC1C(NC(=O)C(NC(=O)C(C(NC(=O)C(NC(=O)C(NC(=O)C(=C)N(C(=O)CCC(NC1=O)C(=O)O)C)C)CC2=CNC3=CC=CC=C32)C(=O)O)C)CCCN=C(N)N)C=CC(=CC(C)C(CC4=CC=CC=C4)OC)C
Isomeric SMILES	C[C@H]1[C@@H](NC(=O)[C@@H](NC(=O)[C@H]([C@@H](NC(=O)[C@@H](NC(=O)[C@H](NC(=O)C(=C)N(C(=O)CC[C@@H](NC1=O)C(=O)O)C)C)CC2=CNC3=CC=CC=C32)C(=O)O)C)CCCN=C(N)N)/C=C/C(=C/[C@H](C)[C@H](CC4=CC=CC=C4)OC)/C
PubChem CID	101619976
Molecular Weight	1068.22

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Chemical and Physical Properties

Solubility	Soluble in methanol or DMSO
Sensitivity	Soluble in methanol or DMSO

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