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Metolazone - 10mM in DMSO, high purity , CAS No.17560-51-9(DMSO), Thiazide-sensitive sodium-chloride cotransporter inhibitor

COA

Grade & Purity:

Moligand™

10mM in DMSO

Cas Number: 17560-51-9(DMSO)
Molecular Weight: 365.83

In stock

Item Number

M408779

Grouped product items
SKU	Size	Availability	Price	Qty
M408779-1ml	1ml	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$321.90

Potent peripheral-type benzodiazepine receptor inhibitor

View related series

Compound libraries (12325)

Basic Description

Synonyms	SR 720-22 \| 7-chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo-6-quinazolinesulfonamide
Specifications & Purity	Moligand™, 10mM in DMSO
Biochemical and Physiological Mechanisms	Metolazone (SR 720-22) is a diuretic that primarily used to treat congestive heart failure and high blood pressure.
Storage Temp	Store at -80°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Thiazide-sensitive sodium-chloride cotransporter inhibitor
Product Description	Information Metolazone (SR 720-22) is a diuretic that primarily used to treat congestive heart failure and high blood pressure. In vitro In vivo Cell Data cell lines：MM-1S, MM-1R, RPMI-8226/S, OPM-1, OCI-My5, SKMM2, KMS-12-BM, XG-1, L363, S6B45 cells and et al. Concentrations： Incubation Time： Powder Purity:≥99%

Product Properties

ALogP	2.463
hba_count	3
HBD Count	2
Rotatable Bond	2

Associated Targets(Human)

CA7 Tclin Carbonic anhydrase 7 (1 Activities)

Discover Target: CA7

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

Smiles	CC1NC2=CC(=C(C=C2C(=O)N1C3=CC=CC=C3C)[S](N)(=O)=O)Cl
Molecular Weight	365.83
Reaxy-Rn	965506
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=965506&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Chemical and Physical Properties

DMSO(mg / mL) Max Solubility	73
DMSO(mM) Max Solubility	199.55
Water(mg / mL) Max Solubility	<1

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