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Methylnissolin - 99%, high purity , CAS No.73340-41-7

COA

Grade & Purity:

≥99%

Cas Number: 73340-41-7
Molecular Weight: 300.3
PubChem CID: 14077830

In stock

Item Number

M650619

Grouped product items
SKU	Size	Availability	Price
M650619-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$180.90
M650619-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$450.90
M650619-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$760.90

Flavonoids Other Flavonoids Phenols Monophenols

View related series

ERK (132) Flavonoids Other Flavonoids Phenols Monophenols (1) MAPK/ERK Pathway (546) PDGFR (109) Protein Tyrosine Kinase/RTK (1314) Receptor Tyrosine Kinase (1260) Stem Cell/Wnt (1019)

Basic Description

Synonyms	(6ar,11ar)-9,10-dimethoxy6a,11a-dihydro-6h-benzofurano [3,2-c]chromen-3-ol \| C17416 \| (6aR,11aR)-9,10-dimethoxy-6a,11a-dihydro-6H-benzofuro[3,2-c]chromen-3-ol \| HY-N2484 \| CS-0022755 \| XM173149 \| CHEBI:81072 \| Q27155029 \| MS-24325 \| Methylnissolin \| DTXSI
Specifications & Purity	≥99%
Biochemical and Physiological Mechanisms	Methylnissolin (Astrapterocarpan), isolated from Astragalus membranaceus , inhibits platelet-derived growth factor (PDGF) -BB-induced cell proliferation with an IC 50 of 10 μM. Methylnissolin inhibits PDGF-BB-induced phosphorylation of extracellular signa
Storage Temp	Protected from light,Store at -80°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	Methylnissolin (Astrapterocarpan), isolated from Astragalus membranaceus , inhibits platelet-derived growth factor (PDGF) -BB-induced cell proliferation with an IC 50 of 10 μM. Methylnissolin inhibits PDGF-BB-induced phosphorylation of extracellular signal-regulated kinase 1/2 (ERIC1/2) mitogen-activated protein (MAP) kinase. Methylnissolin inhibits PDGF-BB-induced vascular smooth muscle cell proliferation by inhibition of the ERK1/2 MAP kinase cascade Form:Solid IC50& Target:PDGFR 10 μM (IC 50 ) ERK1 ERK2

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Phenylpropanoids and polyketides
  - Class Isoflavonoids
    - Subclass Furanoisoflavonoids

Kingdom	Organic compounds
Superclass	Phenylpropanoids and polyketides
Class	Isoflavonoids
Subclass	Furanoisoflavonoids
Intermediate Tree Nodes	Not available
Direct Parent	Pterocarpans
Alternative Parents	Isoflavanols 1-benzopyrans Coumarans Benzofurans Anisoles Alkyl aryl ethers 1-hydroxy-2-unsubstituted benzenoids Oxacyclic compounds Hydrocarbon derivatives
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	Pterocarpan - Isoflavanol - Isoflavan - Chromane - 1-benzopyran - Benzopyran - Coumaran - Benzofuran - Anisole - 1-hydroxy-2-unsubstituted benzenoid - Alkyl aryl ether - Benzenoid - Oxacycle - Organoheterocyclic compound - Ether - Organic oxygen compound - Hydrocarbon derivative - Organooxygen compound - Aromatic heteropolycyclic compound
Description	This compound belongs to the class of organic compounds known as pterocarpans. These are benzo-pyrano-furano-benzene compounds, containing the 6H-[1]benzofuro[3,2-c]chromene skeleton. They are derivatives of isoflavonoids.
External Descriptors	pterocarpans
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Names and Identifiers

IUPAC Name	(6aR,11aR)-9,10-dimethoxy-6a,11a-dihydro-6H-[1]benzofuro[3,2-c]chromen-3-ol
INCHI	InChI=1S/C17H16O5/c1-19-13-6-5-10-12-8-21-14-7-9(18)3-4-11(14)15(12)22-16(10)17(13)20-2/h3-7,12,15,18H,8H2,1-2H3/t12-,15-/m0/s1
InChIKey	UOVGCLXUTLXAEC-WFASDCNBSA-N
Smiles	COC1=C(C2=C(C=C1)C3COC4=C(C3O2)C=CC(=C4)O)OC
Isomeric SMILES	COC1=C(C2=C(C=C1)[C@@H]3COC4=C([C@@H]3O2)C=CC(=C4)O)OC
Alternate CAS	73340-41-7
PubChem CID	14077830
Molecular Weight	300.3

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Chemical and Physical Properties

Solubility	DMSO : 50 mg/mL (166.49 mM; Need ultrasonic)
Molecular Weight	300.300 g/mol
XLogP3	2.600
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	2
Exact Mass	300.1 Da
Monoisotopic Mass	300.1 Da
Topological Polar Surface Area	57.200 Å²
Heavy Atom Count	22
Formal Charge	0
Complexity	403.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	2
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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