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Methylenediphosphonic acid - ≥97%, high purity , CAS No.1984-15-2

    Grade & Purity:
  • ≥97%
In stock
Item Number
M132702
Grouped product items
SKU Size
Availability
Price Qty
M132702-1g
1g
3
$59.90
M132702-5g
5g
3
$199.90
M132702-25g
25g
2
$699.90

Basic Description

Synonyms MDP | Acide medronique (INN-French) | Methylene bis-phosphonic acid | 73OS0QIN3O | HY-108309 | MEDRONIC ACID | STL302043 | CAS-1984-15-2 | DTXCID6025696 | EINECS 217-851-0 | Methylene-1,1-bisphosphonic acid | NCGC00037856-01 | MEDRONIC ACID [MI] | Medrona
Specifications & Purity ≥97%
Storage Temp Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Product Description

A radioactive compound used for skeletal imaging.


application:

Methylenediphosphonic acid is a radioactive compound used for skeletal imaging. MDP has been used as a chelating agent to vary calcium levels in cell culture in a study of caffeine storage in bovine chromaffin cells.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Organic acids and derivatives
Class Organic phosphonic acids and derivatives
Subclass Bisphosphonates
Intermediate Tree Nodes Not available
Direct Parent Bisphosphonates
Alternative Parents Organic phosphonic acids  Organopnictogen compounds  Organophosphorus compounds  Organic oxides  Hydrocarbon derivatives  
Molecular Framework Aliphatic acyclic compounds
Substituents Bisphosphonate - Organophosphonic acid - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organophosphorus compound - Aliphatic acyclic compound
Description This compound belongs to the class of organic compounds known as bisphosphonates. These are organic compounds containing two phosphonate groups linked together through a carbon atoms.
External Descriptors 1,1-bis(phosphonic acid)

Associated Targets(Human)

CA2 Tclin Carbonic anhydrase II (17698 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
THRB Tclin Thyroid hormone receptor beta-1 (7926 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CA1 Tclin Carbonic anhydrase I (13240 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CA5A Tclin Carbonic anhydrase VA (1168 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
OTC Tchem Ornithine carbamoyltransferase (24 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CA9 Tclin Carbonic anhydrase IX (8255 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
A549 (127892 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HSD17B10 Tchem Endoplasmic reticulum-associated amyloid beta-peptide-binding protein (20669 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
KDM4E Tchem Lysine-specific demethylase 4D-like (40243 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
BAZ2B Tchem Bromodomain adjacent to zinc finger domain protein 2B (56204 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Hydroxyapatite (165 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Associated Targets(non-human)

CA4 Carbonic anhydrase IV (1713 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Mapk1 MAP kinase ERK2 (650 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Mmp2 Matrix metalloproteinase-2 (12 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Hdac6 Histone deacetylase 6 (222 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Escherichia coli (133304 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
pfk 6-phospho-1-fructokinase (7870 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Fe(3+)-Zn(2+) purple acid phosphatase (65 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
fba Putative fructose-1,6-bisphosphate aldolase (15559 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
traI Type IV secretion-like conjugative transfer relaxase protein TraI (23 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

Pubchem Sid 504752734
Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504752734
IUPAC Name phosphonomethylphosphonic acid
INCHI InChI=1S/CH6O6P2/c2-8(3,4)1-9(5,6)7/h1H2,(H2,2,3,4)(H2,5,6,7)
InChIKey MBKDYNNUVRNNRF-UHFFFAOYSA-N
Smiles C(P(=O)(O)O)P(=O)(O)O
Isomeric SMILES C(P(=O)(O)O)P(=O)(O)O
WGK Germany 3
RTECS SZ9138000
Molecular Weight 176.00
Beilstein 1(4)3071
Reaxy-Rn 1708494
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1708494&ln=

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

11 results found

Lot Number Certificate Type Date Item
A2503667 Certificate of Analysis Dec 20, 2024 M132702
A2503675 Certificate of Analysis Dec 20, 2024 M132702
A2503678 Certificate of Analysis Dec 20, 2024 M132702
I2404516 Certificate of Analysis Aug 27, 2024 M132702
I2404517 Certificate of Analysis Aug 27, 2024 M132702
I2404518 Certificate of Analysis Aug 27, 2024 M132702
J22111138 Certificate of Analysis Jul 10, 2024 M132702
H2413050 Certificate of Analysis Jul 09, 2024 M132702
J22111167 Certificate of Analysis Jul 09, 2024 M132702
L2325025 Certificate of Analysis Aug 08, 2022 M132702
D2009044 Certificate of Analysis Feb 21, 2022 M132702

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Chemical and Physical Properties

Solubility Soluble in water.
Sensitivity Heat & Light sensitive
Melt Point(°C) 204 °C
Molecular Weight 176.000 g/mol
XLogP3 -3.300
Hydrogen Bond Donor Count 4
Hydrogen Bond Acceptor Count 6
Rotatable Bond Count 2
Exact Mass 175.964 Da
Monoisotopic Mass 175.964 Da
Topological Polar Surface Area 115.000 Ų
Heavy Atom Count 9
Formal Charge 0
Complexity 151.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 1

Solution Calculators

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