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Basic Description
| Synonyms | ERYTHRITOL | meso-Erythritol | 149-32-6 | Phycitol | Erythrit | Mesoerythritol | Phycite | Erythrite | Erythrol | L-Erythritol | (2R,3S)-butane-1,2,3,4-tetrol | Antierythrite | erythro-tetritol | 1,2,3,4-Butanetetrol, (2R,3S)-rel- | Butanetetrol | Erythroglucin | Paycite | C*Eridex | 1,2,3, |
|---|---|
| Specifications & Purity | 10mM in DMSO |
| Storage Temp | Store at -80°C |
| Shipped In |
Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available. |
Taxonomic Classification
Taxonomy Tree
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Kingdom
Organic compounds
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Superclass
Organic oxygen compounds
- Class Organooxygen compounds
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Superclass
Organic oxygen compounds
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organic oxygen compounds |
| Class | Organooxygen compounds |
| Subclass | Carbohydrates and carbohydrate conjugates |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Sugar alcohols |
| Alternative Parents | Secondary alcohols Polyols Primary alcohols Hydrocarbon derivatives |
| Molecular Framework | Aliphatic acyclic compounds |
| Substituents | Sugar alcohol - Secondary alcohol - Polyol - Hydrocarbon derivative - Primary alcohol - Alcohol - Aliphatic acyclic compound |
| Description | This compound belongs to the class of organic compounds known as sugar alcohols. These are hydrogenated forms of carbohydrate in which the carbonyl group (aldehyde or ketone, reducing sugar) has been reduced to a primary or secondary hydroxyl group. |
| External Descriptors | butane-1,2,3,4-tetrol |
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Associated Targets(Human)
SNCA
Tchem
Alpha-synuclein (10960 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Associated Targets(non-human)
ampC
Beta-lactamase AmpC (62480 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Hdac6
Histone deacetylase 6 (222 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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rep
Replicase polyprotein 1ab (378 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Mechanisms of Action
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Names and Identifiers
| IUPAC Name | (2S,3R)-butane-1,2,3,4-tetrol |
|---|---|
| INCHI | InChI=1S/C4H10O4/c5-1-3(7)4(8)2-6/h3-8H,1-2H2/t3-,4+ |
| InChIKey | UNXHWFMMPAWVPI-ZXZARUISSA-N |
| Smiles | C(C(C(CO)O)O)O |
| Isomeric SMILES | C([C@H]([C@H](CO)O)O)O |
| WGK Germany | 3 |
| RTECS | KF2000000 |
| Molecular Weight | 122.12 |
| Beilstein | 1719753 |
| Reaxy-Rn | 1735878 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1735878&ln= |
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
| Sensitivity | Moisture sensitive. |
|---|---|
| Boil Point(°C) | 329-331°C |
| Melt Point(°C) | 121.5°C |
| Molecular Weight | 122.120 g/mol |
| XLogP3 | -2.300 |
| Hydrogen Bond Donor Count | 4 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 3 |
| Exact Mass | 122.058 Da |
| Monoisotopic Mass | 122.058 Da |
| Topological Polar Surface Area | 80.900 Ų |
| Heavy Atom Count | 8 |
| Formal Charge | 0 |
| Complexity | 48.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 2 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
Citations of This Product
| 1. Jinsong He, Tingyan Deng, Linzhi He, Xiaochan An, K.G. Nadeeshani Nanayakkara, Fei Shen, Yanzong Zhang, Jianmei Zou, Li Zhao. (2023) Design of a novel TA-MoS2 nanosheets interlayer-based loose nanofiltration membrane for enhanced dye/salt separation. DESALINATION, 568 (117004). |
| 2. Jie Li, Benzhi Ju, Shufen Zhang. (2023) Catalyst-free, sustainable epoxy vitrimers from epoxidized soybean oil and natural sugar alcohols. INDUSTRIAL CROPS AND PRODUCTS, 205 (117466). |
| 3. Xueyan Yang, Siman Ren, Yuwei Wang, Gan Yang, Yueyang Li, Chuang Li, Lihong Wang, Lei Yao, Lin Wang. (2023) Volatility Parametrization of Low-Volatile Components of Ambient Organic Aerosols Based on Molecular Formulas. ENVIRONMENTAL SCIENCE & TECHNOLOGY, 57 (31): (11595–11604). |
| 4. Bo Zhang, Zhen Li, Liwei Wang. (2023) Novel design and fabrication of form-stable cellulose nanofiber-based phase change composites via click chemistry, coordination reaction, and solvent exchange. CHEMICAL ENGINEERING JOURNAL, 471 (144417). |
| 5. Shengyuan Ye, Yang Cheng, Zheng Guo, Xingguo Wang, Wei Wei. (2023) A lipid toolbox of sugar alcohol fatty acid monoesters for single-component lipid nanoparticles with temperature-controlled release. COLLOIDS AND SURFACES B-BIOINTERFACES, 228 (113426). |
| 6. Zheng Cui, Yu Chen, Dan Meng, Shuheng Wang, Tongbing Sun, Jun Sun, Hongfei Li, Xiaoyu Gu, Sheng Zhang. (2023) Reactive flame-retardants prepared by transesterification between erythritol and dimethyl methyl phosphonate for rigid polyurethane foams. POLYMER DEGRADATION AND STABILITY, 208 (110238). |
| 7. Tengjing Gong, Danting Shi, Zhigao Zhu, Bin Liu, Senlin Shao. (2023) Polyamide Thin-Film Composite Janus Membranes Avoiding Direct Contact between Feed Liquid and Hydrophobic Pores for Excellent Wetting Resistance in Membrane Distillation. ACS ES&T Water, 3 (1): (176–184). |
| 8. Wenjuan Qiu, Yu Bai, Yutang Fang, Shuangfeng Wang. (2022) Preparation and thermal properties of novel inorganic-organic eutectic composite material with high latent heat and thermal conductivity based on aluminum sulfate salt. Journal of Energy Storage, 55 (105364). |
| 9. Kaiming Fan, Yanling Liu, Xiaoping Wang, Peng Cheng, Shengji Xia. (2022) Comparison of polyamide, polyesteramide and polyester nanofiltration membranes: properties and separation performance. SEPARATION AND PURIFICATION TECHNOLOGY, 297 (121579). |
| 10. Qingjiang Cheng, Xiuli Cheng, Xue Wang, Peixing Du, Chenzhen Liu, Zhonghao Rao. (2022) Supercooling regulation and thermal property optimization of erythritol as phase change material for thermal energy storage. Journal of Energy Storage, 52 (105000). |
| 11. Xiaosheng Du, Jiuao Wang, Linzhao Jin, Sha Deng, Yi Dong, Shaojian Lin. (2022) Dopamine-Decorated Ti3C2Tx MXene/Cellulose Nanofiber Aerogels Supported Form-Stable Phase Change Composites with Superior Solar–Thermal Conversion Efficiency and Extremely High Thermal Storage Density. ACS Applied Materials & Interfaces, 14 (13): (15225–15234). |
| 12. Lehui Tu, Yunlong Shi, Chunying Zhu, Taotao Fu, Xiqun Gao, Youguang Ma. (2022) Volumetric and Viscometric Properties of Sugar Alcohols in Glycylglycine–Water Mixtures from 293.15 to 333.15 K. JOURNAL OF CHEMICAL AND ENGINEERING DATA, 67 (2): (305–320). |
| 13. Huijuan Li, Shunguo Qiu, Li Chen, Taotao Fan, Xiong Peng, Zongcheng Yan. (2022) Ternary-like Aqueous Biphasic Systems Composed of Betaine-Polyol Deep Eutectic Solvents and n-Propanol. JOURNAL OF CHEMICAL AND ENGINEERING DATA, 67 (1): (212–220). |
| 14. Zhaodong Huang, Tairan Wang, Xinliang Li, Huilin Cui, Guojin Liang, Qi Yang, Ze Chen, Ao Chen, Ying Guo, Jun Fan, Chunyi Zhi. (2021) Small-Dipole-Molecule-Containing Electrolytes for High-Voltage Aqueous Rechargeable Batteries. ADVANCED MATERIALS, 34 (4): (2106180). |
| 15. Xiang Qin, Nianrong Feng, Zhe Kang, Dongying Hu. (2021) Construction of wood-based cellulose micro-framework composite form-stable multifunctional materials with thermal and electrical response via incorporating erythritol-urea (thiourea)-carbon nanotubes. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 184 (538). |
| 16. Biao Feng, Yu-Hong Zhang, Jing Tu, Li-Wu Fan, Zi-Tao Yu. (2021) Correlating the thermal contact resistance between metal/erythritol interfaces with surface roughness and contact pressure. INTERNATIONAL JOURNAL OF HEAT AND MASS TRANSFER, 176 (121407). |
| 17. Yu Jun, Liang Jiezhen, Chen Xiaopeng, Wang Linlin, Wei Xiaojie, Qin Yanmin, Li Youqi, Ling Youkang. (2021) Reaction network and kinetics for the one-pot hydrogenolysis of cellulose to ethylene glycol over NiOx-WOy-Cu/MgAl2O4. Reaction Kinetics Mechanisms and Catalysis, 133 (1): (55-71). |
| 18. Shao Xuefeng, Yang Sheng, Chen Chenlin, Fan Liwu, Yu Zitao. (2021) Temperature-Dependent Rheological Behaviors of Binary Eutectic Mixtures of Sugar Alcohols for Latent Heat Storage: A Comparative Study with Pure Sugar Alcohols. Journal of Thermal Science, 30 (6): (2002-2014). |
| 19. Ni Tan, Ting Xie, Yang Feng, Ping Hu, Qi Li, Liu-Mo Jiang, Wen-Bo Zeng, Ju-Lan Zeng. (2020) Preparation and characterization of erythritol/sepiolite/exfoliated graphite nanoplatelets form-stable phase change material with high thermal conductivity and suppressed supercooling. SOLAR ENERGY MATERIALS AND SOLAR CELLS, 217 (110726). |
| 20. Hua Xia, Zhou Xin, Du GenLai, Xu Yong. (2020) Resolving the formidable barrier of oxygen transferring rate (OTR) in ultrahigh-titer bioconversion/biocatalysis by a sealed-oxygen supply biotechnology (SOS). Biotechnology for Biofuels, 13 (1): (1-12). |
| 21. Gan Xiaorong, Zhao Huimin, Schirhagl Romana, Quan Xie. (2019) Non enzymatic fluorometric determination of glucose by using quenchable g-C3N4 quantum dots. MICROCHIMICA ACTA, 186 (12): (1-10). |
| 22. Yong-Gang Xia, Si-Miao Yu, Jun Liang, Bing-You Yang, Hai-Xue Kuang. (2020) Chemical fingerprinting techniques for the differentiation of polysaccharides from genus Astragalus. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 178 (112898). |
| 23. Biao Feng, Li-Wu Fan, Yi Zeng, Jing-Yu Ding, Xue-Feng Shao. (2019) Atomistic insights into the effects of hydrogen bonds on the melting process and heat conduction of erythritol as a promising latent heat storage material. INTERNATIONAL JOURNAL OF THERMAL SCIENCES, 146 (106103). |
| 24. Chen Jun, Ding Amin, Zhou Yifeng, Chen Pengpeng, Xu Ying, Nie Wangyan. (2019) Indometacin-loaded micelles based on star-shaped PLLA-TPGS copolymers: effect of arm numbers on drug delivery. COLLOID AND POLYMER SCIENCE, 297 (10): (1321-1330). |
| 25. Yongyi Yu, Yajun Zhang, Cebin Hu, Xinyuan Zou, Yang Lin, Yangyuan Xia, Lijun You. (2019) Chemistry and immunostimulatory activity of a polysaccharide from Undaria pinnatifida. FOOD AND CHEMICAL TOXICOLOGY, 128 (119). |
| 26. Yong-Gang Xia, Tian-Long Wang, Si-Miao Yu, Jun Liang, Hai-Xue Kuang. (2019) Structural characteristics and hepatoprotective potential of Aralia elata root bark polysaccharides and their effects on SCFAs produced by intestinal flora metabolism. CARBOHYDRATE POLYMERS, 207 (256). |
| 27. Xue-Feng Shao, Chao Wang, Yong-Jian Yang, Biao Feng, Zi-Qin Zhu, Wu-Jun Wang, Yi Zeng, Li-Wu Fan. (2018) Screening of sugar alcohols and their binary eutectic mixtures as phase change materials for low-to-medium temperature latent heat storage. (Ⅰ): Non-isothermal melting and crystallization behaviors. ENERGY, 160 (1078). |
| 28. Lu Dai, Cui Tai, Yaling Shen, Yali Guo, Fei Tao. (2019) Biosynthesis of 1,4-butanediol from erythritol using whole-cell catalysis. BIOCATALYSIS AND BIOTRANSFORMATION, 37 (2): (92-96). |
| 29. Feng Sha, Yucong Zheng, Jiao Chen, Kequan Chen, Fei Cao, Ming Yan, Pingkai Ouyang. (2018) D-Tagatose manufacture through bio-oxidation of galactitol derived from waste xylose mother liquor. GREEN CHEMISTRY, 20 (10): (2382-2391). |
| 30. Shile Shen, Shujuan Tan, Sai Wu, Cheng Guo, Juan Liang, Qian Yang, Guoyue Xu, Jie Deng. (2018) The effects of modified carbon nanotubes on the thermal properties of erythritol as phase change materials. ENERGY CONVERSION AND MANAGEMENT, 157 (41). |
| 31. Ding Amin, Zhou Yifeng, Chen Pengpeng, Nie Wangyan. (2017) Ibuprofen-loaded micelles based on star-shaped erythritol-core PLLA-PEG copolymer: effect of molecular weights of PEG. COLLOID AND POLYMER SCIENCE, 295 (9): (1609-1619). |
| 32. Zhen-Gang Ma, Rui Ma, Xiao-Lin Xiao, Yong-Hui Zhang, Xin-Zi Zhang, Nan Hu, Jin-Lai Gao, Yu-Feng Zheng, De-Li Dong, Zhi-Jie Sun. (2016) Azo polymeric micelles designed for colon-targeted dimethyl fumarate delivery for colon cancer therapy. Acta Biomaterialia, 44 (323). |
| 33. Teng Lijing, Nie Wangyan, Zhou Yifeng, Chen Pengpeng. (2016) Synthesis and characterization of star-shaped poly(l-lactide)s with an erythritol core and evaluation of their rifampicin-loaded microspheres for controlled drug delivery. POLYMER BULLETIN, 73 (1): (97-112). |
| 34. Xiang Liu, Yonghong Hu, Wenge Yang, Yan Liu, Mengmeng Liang. (2013) Solubility of erythritol in methanol, ethanol and methanol + ethanol: Experimental measurement and thermodynamic modeling. FLUID PHASE EQUILIBRIA, 360 (134). |
| 35. Junhui Xue, Xiaohui Hua, Weihong Li, Limin Yang, Yizhuang Xu, Guozhong Zhao, Gaohui Zhang, Chunping Li, Kexin Liu, Jia’er Chen, Jinguang Wu. (2012) Sugar–metal ion interactions: the coordination behaviors of lanthanum with erythritol. CARBOHYDRATE RESEARCH, 361 (12). |
| 36. Chonghui Wei, Shu Zhu, Jiacheng Lu, Aoran Guan, Yan Sun, Liyun Zeng, Jinghao Fu, Xingyu Luo. (2024) Engineering the nanozyme hydrogel beads by polyvinyl alcohol/chitosan encapsulation with recyclable and sustainable catalytic activity for visual analysis of hydrogen peroxide. ANALYTICA CHIMICA ACTA, 1320 (343017). |
| 37. Hao Yan, Junsheng Wang, Cong Du, Zheng Li, Hua Yuan, Zhen Xu, Yeqiang Tan. (2024) Hydrogen Bond Mediated Strong Plasticization for High Performance Alginate Plastics. ADVANCED MATERIALS, (2400648). |
| 38. Yugang Shu, Jiaguang Zheng, Chengguo Yan, Ao Xia, Meiling Lv, Zhenxuan Ma, Zhendong Yao. (2024) Hydrogen release of NaBH4 below 60 °C with binary eutectic mixture of xylitol and erythritol additive. CHINESE JOURNAL OF CHEMICAL ENGINEERING, 71 (225). |
| 39. Rui Hong, Ri-Tong Lan, Yue Ren, Lu Xu, Yun-Xiang Xu, Nouman Ali Shah, Rizwan M. Gul, Shishu Huang, Lingli Li, Jia-Zhuang Xu, Zhong-Ming Li, Ka Li. (2024) Insights into synergic antioxidant effects for vitamin E and sugar alcohol stabilized ultrahigh molecular weight polyethylene composites for artificial joints. POLYMER, 295 (126773). |
| 40. Jiayu Xie, Xuran Jin, Hong Cheng, Wei Chen, Wancheng Yu, Linlin Wang. (2024) Molecular origin of the plasticizing effect difference of glycerol with other polyols on plasticizing polyvinyl alcohol (PVA) as elucidated by solid-state NMR. INDUSTRIAL CROPS AND PRODUCTS, 220 (119246). |
| 41. Gao Xuerui, Li Ping, Qin Yuan, Bai Chengling, Gu Zhengyang, Yu Shuili. (2024) Negative rejection phenomenon in the mixed salt nanofiltration: Law and mechanism. DESALINATION, 583 (117667). |
| 42. Pengyu Sun, Feiyu Gao, Wei Shi, Hengyuan Zhang, Shiao Du, Wei Chen, Meng Li. (2025) Preparation and application of nano dendritic polyurethane for high-efficiency boron adsorption. CHINESE JOURNAL OF CHEMICAL ENGINEERING, |
| 43. Tingyan Deng, Zhen Cao, Fan Ni, Li Zhao, Fei Shen, Jianmei Zou, Yanzong Zhang, Yating Chen, Jinsong He. (2025) Quantitative assessment of structure-performance relationship of loose nanofiltration membranes with TA-MoS2 interlayer for effective dye/salt separation. SEPARATION AND PURIFICATION TECHNOLOGY, 356 (129902). |
| 44. Hang Liu, Penghui Cao, Ying Chen, Can Chen, Sicheng Fan, Chuanchang Li, Huali Zhu, MengDi Wu, Juan Yang. (2024) Stabilization of flake Zn powder anodes via designing functional additives in electrolytes for aqueous Zn ion batteries. Journal of Energy Chemistry, |
| 45. Chongyang Wei, Yi Li, Jinliang Song, Jinxing Cheng, Zhongfeng Tang. (2024) Supercooling suppression and thermal conductivity enhancement of erythritol using graphite foam with ultrahigh thermal conductivity for thermal energy storage. INTERNATIONAL COMMUNICATIONS IN HEAT AND MASS TRANSFER, 153 (107392). |
| 46. Jia Mi, Yingchun Li, Wensheng Wang, Zhimao Li, Tong Liu, Guang Nie, Zheyu Zhang. (2025) Synthesis and characterization of erythritol-modified poly(butylene adipate -co- terephthalate). Materials Today Communications, 42 (111318). |
| 47. Chenzhen Liu, Baohuan Li, Siwen Wang, Peng Yang, Kai Qi, Guangtong Zhang, Zhonghao Rao. (2025) Synthesis of alumina porous ceramics to enhance heat transfer and control Supercooling in sugar alcohol phase change materials for thermal energy storage. Journal of Energy Storage, 113 (115627). |
| 48. Lihong Gan, Jin Zhang, Yangtao Wu, Zhuo Chen, Zhenyu Zhao, Shihong Lin, Yi Jiang. (2024) Tailoring Polyelectrolyte Multilayer Nanofiltration Membranes by Aerosol-Assisted Printing: Insights into Membrane Formation Mechanisms. ENVIRONMENTAL SCIENCE & TECHNOLOGY, |
| 49. Xinqing Duan, Lei Li, Zehui Peng, Mingqiang Wang, Yanxin Liu, Dar-Jen Hsieh, Kuan-Chang Chang. (2024) Ultralow Power, Cleft Size-Adjustable and pH-Sensitive Hyaluronic Acid (HA) Biodevices for Acid-Sensing Ion Channels Emulation. Small, (2405207). |
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