Basic Description

Synonyms	UH-AC 62XX \| Meloxicam (JAN/USP/INN) \| Meloxoral \| MLS006011422 \| QMIIZ ODT \| AMOXICILLIN CRYSTALLINE \| C14H13N3O4S2 \| MELOXICAM [EP MONOGRAPH] \| Meloxicam Solution for Injection \| VG2QF83CGL \| Vivlodex \| BIDD:GT0726 \| Emdocam \| Movatec \| Parocin \| Metaca
Specifications & Purity	Moligand™, ≥98%
Biochemical and Physiological Mechanisms	Meloxicam, a non-steroidal anti-inflammatory agent, has been reported to inhibit the inducible isoform of Cox-2. Meloxicam is an inhibitor selective for Cox-2 (IC50 of 4.7 μM) over Cox-1 (IC50 of 36.6 μM). Studies suggest that Meloxicam is Cox-2 preferent
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Inhibitor of COX-1;Inhibitor of COX-2
Note	Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description	Meloxicam (Mobic) is a nonsteroidal anti-inflammatory agent with analgesic and fever reducer effects. An inhibitor of Cox-1 and Cox-2, selective for Cox-2.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
  - Class Benzothiazines

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
Class	Benzothiazines
Subclass	Not available
Intermediate Tree Nodes	Not available
Direct Parent	Benzothiazines
Alternative Parents	Alpha amino acids and derivatives N-arylamides 2,5-disubstituted thiazoles Organosulfonamides Benzenoids 1,2-thiazines Vinylogous acids Heteroaromatic compounds Secondary carboxylic acid amides Azacyclic compounds Organopnictogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	Alpha-amino acid or derivatives - Benzothiazine - N-arylamide - 2,5-disubstituted 1,3-thiazole - Ortho-thiazine - Benzenoid - Organosulfonic acid amide - Azole - Heteroaromatic compound - Vinylogous acid - Thiazole - Organosulfonic acid or derivatives - Organic sulfonic acid or derivatives - Carboxamide group - Secondary carboxylic acid amide - Azacycle - Carboxylic acid derivative - Organic oxygen compound - Organic nitrogen compound - Carbonyl group - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organonitrogen compound - Organooxygen compound - Aromatic heteropolycyclic compound
Description	This compound belongs to the class of organic compounds known as benzothiazines. These are organic compounds containing a benzene fused to a thiazine ring (a six-membered ring with four carbon atoms, one nitrogen atom and one sulfur atom).
External Descriptors	monocarboxylic acid amide - 1,3-thiazole - benzothiazine
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

PTGS1 Tclin Prostaglandin G/H synthase 1 (1 Activities)

Discover Target: PTGS1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PTGS2 Tclin Prostaglandin G/H synthase 2 (6 Activities)

Discover Target: PTGS2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

Pubchem Sid	504771345
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/504771345
IUPAC Name	4-hydroxy-2-methyl-N-(5-methyl-1,3-thiazol-2-yl)-1,1-dioxo-1λ6,2-benzothiazine-3-carboxamide
INCHI	InChI=1S/C14H13N3O4S2/c1-8-7-15-14(22-8)16-13(19)11-12(18)9-5-3-4-6-10(9)23(20,21)17(11)2/h3-7,18H,1-2H3,(H,15,16,19)
InChIKey	ZRVUJXDFFKFLMG-UHFFFAOYSA-N
Smiles	CC1=CN=C(S1)NC(=O)C2=C(C3=CC=CC=C3S(=O)(=O)N2C)O
Isomeric SMILES	CC1=CN=C(S1)NC(=O)C2=C(C3=CC=CC=C3S(=O)(=O)N2C)O
RTECS	DL0702000
UN Number	2811
Packing Group	III
Molecular Weight	351.4
Reaxy-Rn	5886369
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=5886369&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

11 results found

Lot Number	Certificate Type	Date	Item
F2527089	Certificate of Analysis	Jul 10, 2025	M129228
K2217988	Certificate of Analysis	Sep 14, 2024	M129228
K2217985	Certificate of Analysis	Sep 14, 2024	M129228
L2409105	Certificate of Analysis	Sep 14, 2024	M129228
K2217942	Certificate of Analysis	Sep 14, 2024	M129228
K2217986	Certificate of Analysis	Sep 14, 2024	M129228
D2422192	Certificate of Analysis	Mar 26, 2024	M129228
D2422191	Certificate of Analysis	Mar 26, 2024	M129228
G1515087	Certificate of Analysis	May 09, 2023	M129228
D2117281	Certificate of Analysis	Feb 08, 2023	M129228
D2117285	Certificate of Analysis	Feb 08, 2023	M129228

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Chemical and Physical Properties

Solubility	H2O: 0.67 mg/mL (1.91 mM; ultrasound assisted dissolution); DMSO: 25 mg/mL (71.14 mM; ultrasound assisted dissolution (<60 ° C); Ethanol:<1 mg/mL
Sensitivity	Heat sensitive
Melt Point(°C)	255°C
Molecular Weight	351.400 g/mol
XLogP3	3.000
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	2
Exact Mass	351.035 Da
Monoisotopic Mass	351.035 Da
Topological Polar Surface Area	136.000 Å²
Heavy Atom Count	23
Formal Charge	0
Complexity	628.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Gilbert Audira, Jong-Chin Huang, Kelvin H.-C. Chen, Kevin Adi Kurnia, Ross D. Vasquez, Marri Jmelou M. Roldan, Yu-Heng Lai, Chung-Der Hsiao, Cheng-Yo Yen. (2023) A comprehensive painkillers screening by assessing zebrafish behaviors after caudal fin amputation. BIOMEDICINE & PHARMACOTHERAPY, 168 (115641).
2. Zhong-Xia Wang, Kai-Qi Liu, Xiang-Ying Meng, Feng Li, Heng-Ye Li, Hang Gao, Wei Wang. (2023) An eco-friendly fluorometric assay for high-sensitive meloxicam quantitation in biological matrices. ANALYST, 148 (18): (4339-4345).
3. Meizhu Qin, Xinping Hu, Jingyan Guo. (2023) Preparation of a New Type of Expansion Flame Retardant and Application in Polystyrene. Coatings, 13 (4): (733).
4. Jiana Lin, Xiaoyan Ouyang, Yuling Hu, Gongke Li, Qisheng Zhong. (2023) Primary amide-functionalized cyclotricatechylene covalent organic frameworks membrane for efficient enrichment of melamine and its derivatives in migration solution of food contact materials. JOURNAL OF SEPARATION SCIENCE, 46 (6): (202200862).
5. Chenghua Song, Ruichao Wen, Jiaxuan Zhou, Xiaoyan Zeng, Zi Kou, Yufeng Li, Feng Yun, Rongqian Wu. (2022) UV C Light from a Light-Emitting Diode at 275 Nanometers Shortens Wound Healing Time in Bacterium- and Fungus-Infected Skin in Mice. Microbiology Spectrum,
6. Chenghua Song, Ruichao Wen, Jiaxuan Zhou, Xiaoyan Zeng, Zi Kou, Jia Zhang, Tao Wang, Pengkang Chang, Yi Lv, Rongqian Wu. (2022) Antibacterial and Antifungal Properties of a Novel Antimicrobial Peptide GK-19 and Its Application in Skin and Soft Tissue Infections Induced by MRSA or Candida albicans. Pharmaceutics, 14 (9): (1937).
7. Xiaochun Hu, Yuqing Luo, Xianyue Wu, Jiabin Niu, Mingwu Tan, Zhiqiang Sun, Wen Liu. (2022) Heteroatom-doped microporous carbon nanosheets derived from pentaerythritol-melamine for supercapacitors and CO2 capture. Materials Today Energy, 27 (101010).
8. Ya Xu, Ru Zhou, Jingjing Mu, Yanming Ding, Juncheng Jiang. (2022) Synergistic flame retardancy of linear low-density polyethylene with surface modified intumescent flame retardant and zinc borate. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 640 (128400).
9. Xiaoqiang Feng, Zhengyi He, Lingyan Yu, Zhiduo Liu, Gang Wang, Siwei Yang, Guqiao Ding. (2021) Dual-enhanced Raman scattering sensors incorporating graphene plasmonic nanoresonators. Journal of Materials Chemistry C, 9 (37): (12768-12777).
10. Wei Zhu, Xiaoqiang Feng, Zhiduo Liu, Menghan Zhao, Peng He, Siwei Yang, Shiwei Tang, Da Chen, Qinglei Guo, Gang Wang, Guqiao Ding. (2021) Sensitive, Reusable, Surface-Enhanced Raman Scattering Sensors Constructed with a 3D Graphene/Si Hybrid. ACS Applied Materials & Interfaces, 13 (19): (23081–23091).
11. Ru Zhou, Jingjing Mu, Xiaoyan Sun, Yanming Ding, Juncheng Jiang. (2020) Application of intumescent flame retardant containing aluminum diethyphosphinate, neopentyl glycol, and melamine for polyethylene. SAFETY SCIENCE, 131 (104849).
12. Chen Xiao, Xi Zhiyu, Liang Huaibin, Sun Yuhao, Zhong Zhihong, Wang Baofeng, Bian Liuguan, Sun Qingfang. (2019) Melatonin Prevents Mice Cortical Astrocytes From Hemin-Induced Toxicity Through Activating PKCα/Nrf2/HO-1 Signaling in vitro. Frontiers in Neuroscience, 13
13. Tong Wang, Hai-Long Wu, Yong-Jie Yu, Wan-Jun Long, Li Cheng, An-Qi Chen, Ru-Qin Yu. (2019) A simple method for direct modeling of second-order liquid chromatographic data with retention time shifts and holding the second-order advantage. JOURNAL OF CHROMATOGRAPHY A, 1605 (360360).
14. Shouwu Yu, Shujuan Xiao, Zewen Zhao, Xiaowen Huo, Junfu Wei. (2019) Microencapsulated ammonium polyphosphate by polyurethane with segment of dipentaerythritol and its application in flame retardant polypropylene. CHINESE JOURNAL OF CHEMICAL ENGINEERING, 27 (1735).
15. Sung Rae Kim, Myoung Jin Ho, Sang Hyun Kim, Ha Ra Cho, Han Sol Kim, Yong Seok Choi, Young Wook Choi, Myung Joo Kang. (2016) Increased localized delivery of piroxicam by cationic nanoparticles after intra-articular injection. Drug Design Development and Therapy,
16. Wang Yu, Gao Lei, Qin Dongli, Chen Ligang. (2017) Analysis of Melamine in Milk Powder by CNT-MIP with Matrix Solid Phase Dispersion and LC-MS/MS. Food Analytical Methods, 10 (5): (1386-1396).
17. Kim Han Sol, Cho Ha Ra, Ho Myoung Jin, Kang Myung Joo, Choi Yong Seok. (2016) Determination of piroxicam from rat articular tissue and plasma based on LC–MS/MS. ARCHIVES OF PHARMACAL RESEARCH, 39 (12): (1653-1662).
18. Rongli Zhang, Sheng Xu, Ye Zhu, Wei Zhao, Jing Luo, Xiaoya Liu, Dingxing Tang. (2016) Molecularly imprinted nanohybrids based on dopamine-modified poly(γ-glutamic acid) for electrochemical sensing of melamine. BIOSENSORS & BIOELECTRONICS, 85 (381).
19. Xu Xiuzhu, Chen Shuixia, Zhuang Linzhou, Zheng Chunhao, Wu Yingzhu. (2014) Establishment of a novel surface-imprinting system for melamine recognition and mechanism of template–matrix interactions. JOURNAL OF MATERIALS SCIENCE, 49 (7): (2853-2863).
20. Peipei Cheng, Xinting Wang, Qian Liu, Tianshu Yang, Enrui Dai, Wanjing Sha, Huiyan Qu, Hua Zhou. (2024) LuQi Formula attenuates Cardiomyocyte ferroptosis via activating Nrf2/GPX4 signaling axis in heart failure.. PHYTOMEDICINE, (155357).
21. Wenyuan Li, Lin Chen, Minpeng Li, Kaiye Peng, Xuemei Lin, Yifan Feng, Yun Zou, Xia Wu. (2025) Study on chemical composition, anti-inflammatory activity and quality control of the branch bark of Morus alba L.. FITOTERAPIA, 181 (106383).

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SKU	Size	Availability	Price
M129228-5g	5g	3	$46.90
M129228-10g	10g	3	$83.90
M129228-25g	25g	3	$136.90
M129228-100g	100g	3	$492.90

Meloxicam - ≥98%, high purity , CAS No.71125-38-7, Inhibitor of COX-1;Inhibitor of COX-2