Basic Description

Synonyms	Z1255485274 \| 6HG8UB2MUY \| A834035 \| Meglumine 100 microg/mL in Acetonitrile \| CAS-6284-40-8 \| Meglumine (JP17/USP/INN) \| MEGLUMINE [II] \| AB00430469-03 \| Meglumine, Pharmaceutical Secondary Standard; Certified Reference Material \| Megluminum [INN-Latin]
Specifications & Purity	PharmPure™, USP
Storage Temp	Protected from light,Room temperature
Shipped In	Normal
Grade	PharmPure™, USP
Product Description	General Description When working on a pharmaceutical formulation, there are specific considerations to make and challenging hurdles to take before you can successfully launch your final drug product - formulation stability, release kinetics and bioavailability limitations just to name a few. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production. As part of our EMPROVE ® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC ® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines. Application Meglumine EMPROVE ® Essential is a robust pharmaceutical excipient that can provide stability, solubility enhancement and pH modification in solid and liquid formulations.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organic oxygen compounds
  - Class Organooxygen compounds
    - Subclass Carbohydrates and carbohydrate conjugates
      - Level5 Monosaccharides
        Level6 Hexoses

Kingdom	Organic compounds
Superclass	Organic oxygen compounds
Class	Organooxygen compounds
Subclass	Carbohydrates and carbohydrate conjugates
Intermediate Tree Nodes	Monosaccharides
Direct Parent	Hexoses
Alternative Parents	1,3-aminoalcohols Secondary alcohols 1,2-aminoalcohols Polyols Dialkylamines Primary alcohols Organopnictogen compounds Hydrocarbon derivatives
Molecular Framework	Aliphatic acyclic compounds
Substituents	Hexose monosaccharide - 1,3-aminoalcohol - Secondary alcohol - 1,2-aminoalcohol - Secondary amine - Polyol - Secondary aliphatic amine - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Primary alcohol - Organonitrogen compound - Amine - Alcohol - Aliphatic acyclic compound
Description	This compound belongs to the class of organic compounds known as hexoses. These are monosaccharides in which the sugar unit is a is a six-carbon containing moeity.
External Descriptors	secondary amino compound - hexosamine
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

ADRB1 Tclin Adrenergic receptor beta (1214 Activities)

Discover Target: ADRB1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	(2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol
INCHI	InChI=1S/C7H17NO5/c1-8-2-4(10)6(12)7(13)5(11)3-9/h4-13H,2-3H2,1H3/t4-,5+,6+,7+/m0/s1
InChIKey	MBBZMMPHUWSWHV-BDVNFPICSA-N
Smiles	CNCC(C(C(C(CO)O)O)O)O
Isomeric SMILES	CNC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O
WGK Germany	3
Molecular Weight	195.21
Beilstein	385906
Reaxy-Rn	2324336
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2324336&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

7 results found

Lot Number	Certificate Type	Date	Item
H2324001	Certificate of Analysis	Jul 10, 2023	M433157
G2326829	Certificate of Analysis	Jul 07, 2023	M433157
G2326834	Certificate of Analysis	Jul 07, 2023	M433157
B2528641	Certificate of Analysis	Jul 07, 2023	M433157
G2326826	Certificate of Analysis	Jul 07, 2023	M433157
B2423081	Certificate of Analysis	Jul 07, 2023	M433157
K2408155	Certificate of Analysis	Jul 07, 2023	M433157

Chemical and Physical Properties

Sensitivity	Light sensitive
Specific Rotation[α]	-16.5 ° (C=2, H2O)
Melt Point(°C)	129-131.5°C
Molecular Weight	195.210 g/mol
XLogP3	-2.800
Hydrogen Bond Donor Count	6
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	6
Exact Mass	195.111 Da
Monoisotopic Mass	195.111 Da
Topological Polar Surface Area	113.000 Å²
Heavy Atom Count	13
Formal Charge	0
Complexity	134.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	4
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Kong Ruiping, Xu Lingwei, Zhu Li, Sun Yongrong. (2023) Preparation, characterization and evaluation of cefixime ternary inclusion complexes formated by mechanochemical strategy. JOURNAL OF INCLUSION PHENOMENA AND MACROCYCLIC CHEMISTRY, (1-21).
2. Tongtong Pan, Xiangmei Cui. (2023) Gelatin aerogel with good mechanical properties and adjustable physical properties for boron adsorption from salt lake brines: An optimized process. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 251 (126403).
3. Guolong Huang, Yifan Qiu, Lei Bi, Huiyi Wei, Guocong Li, Zhijun Li, Peizhen Ye, Min Yang, Yanfang Shen, Hao Liu, Lu Wang, Hongjun Jin. (2022) PET Imaging of P2X7 Receptor (P2X7R) for Neuroinflammation with Improved Radiosynthesis of Tracer [18F]4A in Mice and Non-human Primates. ACS Chemical Neuroscience, 13 (23): (3464–3476).
4. Chun Bai, Kexin Li, Dezhen Fang, Xiushen Ye, Huifang Zhang, Quan Li, Jun Li, Haining Liu, Zhijian Wu. (2021) Efficient separation of boron from salt lake brine using a novel flotation agent synthesized from NMDG and 1-bromooctadecane. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 627 (127178).
5. Mei Hong, Die Li, Bingyu Wang, Jingyu Zhang, Bin Peng, Xiaoling Xu, Yan Wang, Chunyang Bao, Jing Chen, Qiang Zhang. (2021) Cellulose-derived polyols as high-capacity adsorbents for rapid boron and organic pollutants removal from water. JOURNAL OF HAZARDOUS MATERIALS, 419 (126503).
6. Qihong Zhang, Wei Ren, Alexandr V. Dushkin, Weike Su. (2020) Preparation, characterization, in vitro and in vivo studies of olmesartan medoxomil in a ternary solid dispersion with N-methyl-D-glucamine and hydroxypropyl-β-cyclodextrin. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 56 (101546).
7. Yanyun Bai, Jinxing Li, Xiumei Tai, Guoyong Wang. (2020) Preparation, characterization, and properties of novel meglumine-based polysiloxane surfactants. JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY, 84 (236).
8. Ming Zhao, Tianhao Li, Lichao Jia, Huilin Li, Weiyong Yuan, Chang Ming Li. (2019) Pristine-Graphene-Supported Nitrogen-Doped Carbon Self-Assembled from Glucaminium-Based Ionic Liquids as Metal-Free Catalyst for Oxygen Evolution. ChemSusChem, 12 (22): (5041-5050).
9. Lei Hu, Li Gao, Xiaoming Yan, Wenji Zheng, Yan Dai, Ce Hao, Xuemei Wu, Gaohong He. (2019) Proton delivery through a dynamic 3D H-bond network constructed from dense hydroxyls for advanced ion-selective membranes. Journal of Materials Chemistry A, 7 (25): (15137-15144).
10. Jinxing Li, Yanyun Bai, Wanxu Wang, Xiumei Tai, Guoyong Wang. (2019) Green Glucamine-Based Trisiloxane Surfactant: Surface Activity, Aggregate Behavior, and Superspreading on Hydrophobic Surfaces. ACS Sustainable Chemistry & Engineering, 7 (4): (4390–4398).
11. Xueri Nan, Jing Liu, Xiuli Wang, Xianhui Pan, Xiaomei Wang, Xu Zhang. (2018) Preparation of Superhydrophilic Adsorbents with 3DOM Structure by Water-Soluble Colloidal Crystal Templates for Boron Removal from Natural Seawater. ACS Applied Materials & Interfaces, 10 (43): (36918–36925).
12. Qiang Wu, Mingyan Liu, Xiong Wang. (2019) A novel chitosan based adsorbent for boron separation. SEPARATION AND PURIFICATION TECHNOLOGY, 211 (162).
13. Tianhao Li, Daomei Tang, ChangMing Li. (2017) A high active hydrogen evolution reaction electrocatalyst from ionic liquids-originated cobalt phosphide/carbon nanotubes. INTERNATIONAL JOURNAL OF HYDROGEN ENERGY, 42 (21786).
14. Xuefang Ding, Wei Wang, Yazhe Wang, Xiuli Bao, Yu Wang, Cheng Wang, Jian Chen, Fangrong Zhang, Jianping Zhou. (2014) Versatile Reticular Polyethylenimine Derivative-Mediated Targeted Drug and Gene Codelivery for Tumor Therapy. MOLECULAR PHARMACEUTICS, 11 (10): (3307–3321).
15. Xiaoling Xu, Bin Peng, Yanqiu Wang, Yaqi Dong, Hui Wang, Wentong Chen, Yan Liu, Qiang Zhang. (2025) Fabrication of POSS-centered polyester network as high anti-chlorine and anti-fouling separation layer of membrane via successive Photo-ATRP and interfacial polymerization for molecular separation. JOURNAL OF MEMBRANE SCIENCE, 715 (123432).
16. Guo Haikun, Li Xiang, Chai Shengchao, Li Haibin, Li Tingting, Song Shihao, Zuo Peng, Li Haolong. (2025) Flexible supramolecular polymer proton conductors with high mechanical-conductive decoupling ability. Science China-Chemistry, (1-10).
17. Yanzhi Dong, Gang Shu, Yibo Wei, Jinbin Pan, Dong Li, Shao-Kai Sun. (2024) Gram-Scale Synthesis of Renal-Clearable Tantalum Nanodots with High Water Solubility for Computed Tomography Imaging In Vivo. ACS Nano, 18 (36): (25081-25095).
18. Ruihao Wang, Qian Li, Xiyan Sun, Xinyu Jia, Shuxian Li, Li Wei, Xitong Sun. (2025) High efficiency adsorption of boron by sodium alginate/polyethyleneimine/polysiloxane composite aerogel. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, (139784).
19. Ma Li, Pan Jinbin, Shu Gang, Pan Haiyan, Li Jingang, Li Dong, Sun Shaokai. (2024) Non-invasive fast assessment of hepatic injury through computed tomography imaging with renal-clearable Bi-DTPA dimeglumine. Regenerative Biomaterials, 11

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SKU	Size	Availability	Price
M433157-25g	25g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$24.90
M433157-100g	100g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$80.90
M433157-500g	500g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$332.90

Meglumine - USP level, high purity , CAS No.6284-40-8