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Mc-MMAE - 96%, high purity , CAS No.863971-24-8

COA

Grade & Purity:

≥96%

Cas Number: 863971-24-8
Molecular Weight: 911.18

In stock

Item Number

M648597

Grouped product items
SKU	Size	Availability	Price
M648597-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$266.90
M648597-5×1mg	5×1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$532.90
M648597-10×1mg	10×1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$850.90

View related series

Antibody-drug Conjugate/ADC Related (553) Cell Cycle (2830) Cell Cycle/DNA Damage (2602) Cytoskeleton (498) Drug-Linker Conjugates for ADC (104) Microtubule/Tubulin (199)

Basic Description

Specifications & Purity	≥96%
Biochemical and Physiological Mechanisms	Mc-MMAE is a protective group (maleimidocaproyl)-conjugated monomethyl auristatin E (MMAE), which is a potent tubulin inhibitor. Mc-MMAE is a agent-linker conjugate for ADC.
Storage Temp	Store at 2-8°C,Argon charged
Shipped In	Wet ice This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	Mc-MMAE is a protective group (maleimidocaproyl)-conjugated monomethyl auristatin E (MMAE), which is a potent tubulin inhibitor. Mc-MMAE is a agent-linker conjugate for ADC. In Vitro Synthesis of maleimidocaproyl-MMAE (mc-MMAE) requires the addition of maleimidocaproic acid to a solution of MMAE in dichloromethane followed by the addition of diethyl cyanophosphonate and diisopropylethylamine. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:Auristatin

Names and Identifiers

Smiles	O=C1N(CCCCCC(N(C)[C@H](C(N[C@@H](C(C)C)C(N([C@@H]([C@@H](C)CC)[C@@H](CC(N2[C@H]([C@H](OC)[C@H](C(N[C@@H]([C@H](C3=CC=CC=C3)O)C)=O)C)CCC2)=O)OC)C)=O)=O)C(C)C)=O)C(C=C1)=O
Molecular Weight	911.18

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Chemical and Physical Properties

Solubility	DMSO : 180 mg/mL (197.55 mM; Need ultrasonic) H2O : <0.1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble)

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