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Mc-MMAD - ≥96%, high purity , CAS No.1401963-15-2

COA

Grade & Purity:

≥96%

Cas Number: 1401963-15-2
Molecular Weight: 964.26
PubChem CID: 78357802

In stock

Item Number

M125686

Grouped product items
SKU	Size	Availability	Price
M125686-1mg	1mg	1	$399.90
M125686-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,103.90
M125686-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,691.90
M125686-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$3,807.90
M125686-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$6,852.90
M125686-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$12,334.90

View related series

Antibody-drug Conjugate/ADC Related (553) Cell Cycle (2830) Cell Cycle/DNA Damage (2602) Cytoskeleton (498) Drug-Linker Conjugates for ADC (104) Microtubule (1) Microtubule/Tubulin (199) Tubulin Drug-Linker Conjugates for ADC (1)

Basic Description

Specifications & Purity	≥96%
Biochemical and Physiological Mechanisms	Description: Monomethyl auristatin D (MMAD), a potent tubulin inhibitor, is a toxin payload and antibody drug conjugate. For comparison purposes, the ADC A1 -mc-MMAD and/or A1 -vc-MMAD were used. The linker payload, mc-MM
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	Mc-MMAD is a protective group (maleimidocaproyl)-conjugated MMAD. MMAD is a potent tubulin inhibitor. Mc-MMAD is a agent-linker conjugate for ADC。

Names and Identifiers

IUPAC Name	6-(2,5-dioxopyrrol-1-yl)-N-[(2S)-1-[[(2S)-1-[[(3R,4S,5S)-3-methoxy-1-[(2S)-2-[(1R,2R)-1-methoxy-2-methyl-3-oxo-3-[[(1S)-2-phenyl-1-(1,3-thiazol-2-yl)ethyl]amino]propyl]pyrrolidin-1-yl]-5-methyl-1-oxoheptan-4-yl]-methylamino]-3-methyl-1-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]-N-methylhexanamide
INCHI	InChI=1S/C51H77N7O9S/c1-12-34(6)46(56(9)51(65)44(32(2)3)54-49(64)45(33(4)5)55(8)40(59)23-17-14-18-27-58-41(60)24-25-42(58)61)39(66-10)31-43(62)57-28-19-22-38(57)47(67-11)35(7)48(63)53-37(50-52-26-29-68-50)30-36-20-15-13-16-21-36/h13,15-16,20-21,24-26,29,32-35,37-39,44-47H,12,14,17-19,22-23,27-28,30-31H2,1-11H3,(H,53,63)(H,54,64)/t34-,35+,37-,38-,39+,44-,45-,46-,47+/m0/s1
InChIKey	OZUQLKHIIRUJRZ-PGBUMTRMSA-N
Smiles	CCC(C)C(C(CC(=O)N1CCCC1C(C(C)C(=O)NC(CC2=CC=CC=C2)C3=NC=CS3)OC)OC)N(C)C(=O)C(C(C)C)NC(=O)C(C(C)C)N(C)C(=O)CCCCCN4C(=O)C=CC4=O
Isomeric SMILES	CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@@H]([C@@H](C)C(=O)N[C@@H](CC2=CC=CC=C2)C3=NC=CS3)OC)OC)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)N(C)C(=O)CCCCCN4C(=O)C=CC4=O
PubChem CID	78357802
Molecular Weight	964.26

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

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Analytical Chart:

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5 results found

Lot Number	Certificate Type	Date	Item
C2421501	Certificate of Analysis	Mar 06, 2024	M125686
C2421502	Certificate of Analysis	Mar 06, 2024	M125686
C2421503	Certificate of Analysis	Mar 06, 2024	M125686
C2421507	Certificate of Analysis	Mar 06, 2024	M125686
C2421508	Certificate of Analysis	Mar 06, 2024	M125686

Chemical and Physical Properties

Solubility	25°C: DMSO
Molecular Weight	964.300 g/mol
XLogP3	5.500
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	11
Rotatable Bond Count	27
Exact Mass	963.55 Da
Monoisotopic Mass	963.55 Da
Topological Polar Surface Area	216.000 Å²
Heavy Atom Count	68
Formal Charge	0
Complexity	1710.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	9
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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