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MAZ51 - 10mM in DMSO, high purity , CAS No.163655-37-6

COA

Grade & Purity:

10mM in DMSO

Cas Number: 163655-37-6
Molecular Weight: 314.38
PubChem CID: 24906291

In stock

Item Number

M422009

Grouped product items
SKU	Size	Availability	Price	Qty
M422009-1ml	1ml	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$103.90

a vascular endothelial cell growth factor-C inhibitor

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Basic Description

Synonyms	MAZ51 \| 163655-37-6 \| 3-[[4-(dimethylamino)naphthalen-1-yl]methylidene]-1H-indol-2-one \| SCHEMBL3374614 \| MAZ-51;MAZ 51 \| VFCXONOPGCDDBQ-UHFFFAOYSA-N \| BCP31595 \| Q27165368 \| 3-(4-Dimethylaminonaphthalen-1-ylmethylene)-1,3-dihydroindol-2-one \| 3-[[4-(dimethylamino)-1-napht
Specifications & Purity	10mM in DMSO
Storage Temp	Store at -80°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	MAZ51 inhibits vascular endothelial cell growth factor-C (VEGF-C)-induced intracellular phosphorylation of Flt-4 (VEGFR-3) (IC\|50\|= 1 μM). MAZ51 is an inhibitor of Flt-4.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Benzenoids
  - Class Naphthalenes

Kingdom	Organic compounds
Superclass	Benzenoids
Class	Naphthalenes
Subclass	Not available
Intermediate Tree Nodes	Not available
Direct Parent	Naphthalenes
Alternative Parents	Indolines Dialkylarylamines Secondary carboxylic acid amides Lactams Amino acids and derivatives Azacyclic compounds Organopnictogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	Naphthalene - Indole or derivatives - Dihydroindole - Dialkylarylamine - Tertiary aliphatic/aromatic amine - Amino acid or derivatives - Carboxamide group - Lactam - Secondary carboxylic acid amide - Tertiary amine - Carboxylic acid derivative - Azacycle - Organoheterocyclic compound - Organic nitrogen compound - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Amine - Organic oxygen compound - Carbonyl group - Organonitrogen compound - Organooxygen compound - Aromatic heteropolycyclic compound
Description	This compound belongs to the class of organic compounds known as naphthalenes. These are compounds containing a naphthalene moiety, which consists of two fused benzene rings.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Names and Identifiers

IUPAC Name	3-[[4-(dimethylamino)naphthalen-1-yl]methylidene]-1H-indol-2-one
INCHI	InChI=1S/C21H18N2O/c1-23(2)20-12-11-14(15-7-3-4-9-17(15)20)13-18-16-8-5-6-10-19(16)22-21(18)24/h3-13H,1-2H3,(H,22,24)
InChIKey	VFCXONOPGCDDBQ-UHFFFAOYSA-N
Smiles	CN(C)C1=CC=C(C2=CC=CC=C21)C=C3C4=CC=CC=C4NC3=O
Isomeric SMILES	CN(C)C1=CC=C(C2=CC=CC=C21)C=C3C4=CC=CC=C4NC3=O
WGK Germany	3
Molecular Weight	314.38
Reaxy-Rn	27760008
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=27760008&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Chemical and Physical Properties

Refractive Index	n20D1.73 (Predicted)
Boil Point(°C)	553.92° C at 760 mmHg (Predicted)
Melt Point(°C)	222.83° C (Predicted)
Molecular Weight	314.400 g/mol
XLogP3	4.300
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	2
Exact Mass	314.142 Da
Monoisotopic Mass	314.142 Da
Topological Polar Surface Area	32.299 Å²
Heavy Atom Count	24
Formal Charge	0
Complexity	512.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	1
The total count of all stereochemical bonds	1
Covalently-Bonded Unit Count	1

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