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Marinobufogenin - 99%, high purity , CAS No.470-42-8

COA

Grade & Purity:

≥99%

Cas Number: 470-42-8
Molecular Weight: 400.51
PubChem CID: 11969465

In stock

Item Number

M647501

Grouped product items
SKU	Size	Availability	Price	Qty
M647501-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$180.90
M647501-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$550.90

Steroids

View related series

Membrane Transporter (607) Membrane Transporter/Ion Channel (1822) Na+/K+ ATPase (41) Steroids (129)

Basic Description

Synonyms	Denopamine (JAN/INN) \| UNII-3KBT25GV2B \| CLOCORTOLONE (USP-RS) \| CHEBI:146151 \| MARCINOBUFAGIN \| Bufa-20,22-dienolide, 14,15-epoxy-3,5-dihydroxy-, (3.beta.,5.beta.,15.beta.)- \| SCHEMBL1483986 \| 5beta-Bufa-20,22-dienolide, 14,15beta-epoxy-3beta,5-dihydroxy
Specifications & Purity	≥99%
Biochemical and Physiological Mechanisms	Marinobufogenin is a strong inhibitor of Na + /K + ATPase that has been identified in mammalian plasma.
Storage Temp	Protected from light,Store at -80°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	Marinobufogenin is a strong inhibitor of Na + /K + ATPase that has been identified in mammalian plasma Form:Solid IC50& Target:IC50: Na + /K + ATPase

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Lipids and lipid-like molecules
  - Class Steroids and steroid derivatives
    - Subclass Steroid lactones

Kingdom	Organic compounds
Superclass	Lipids and lipid-like molecules
Class	Steroids and steroid derivatives
Subclass	Steroid lactones
Intermediate Tree Nodes	Not available
Direct Parent	Bufanolides and derivatives
Alternative Parents	Naphthopyrans Naphthalenes Pyranones and derivatives Oxanes Tertiary alcohols Heteroaromatic compounds Secondary alcohols Lactones Cyclic alcohols and derivatives Oxacyclic compounds Epoxides Dialkyl ethers Organic oxides Hydrocarbon derivatives
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	Bufanolide-skeleton - Naphthopyran - Naphthalene - Pyranone - Pyran - Oxane - Cyclic alcohol - Heteroaromatic compound - Tertiary alcohol - Lactone - Secondary alcohol - Dialkyl ether - Oxirane - Ether - Oxacycle - Organoheterocyclic compound - Organic oxygen compound - Hydrocarbon derivative - Organic oxide - Alcohol - Organooxygen compound - Aromatic heteropolycyclic compound
Description	This compound belongs to the class of organic compounds known as bufanolides and derivatives. These are steroid lactones containing a pyran-2-one moiety linked to the C17 atom of a cyclopenta[a]phenanthrene derivative.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Names and Identifiers

IUPAC Name	5-[(1R,2S,4R,6R,7R,10S,11R,14S,16S)-14,16-dihydroxy-7,11-dimethyl-3-oxapentacyclo[8.8.0.02,4.02,7.011,16]octadecan-6-yl]pyran-2-one
INCHI	InChI=1S/C24H32O5/c1-21-8-5-15(25)12-23(21,27)10-7-17-16(21)6-9-22(2)18(11-19-24(17,22)29-19)14-3-4-20(26)28-13-14/h3-4,13,15-19,25,27H,5-12H2,1-2H3/t15-,16-,17+,18+,19+,21+,22+,23-,24+/m0/s1
InChIKey	JMNQTHQLNRILMH-OBBGIPBRSA-N
Smiles	CC12CCC(CC1(CCC3C2CCC4(C35C(O5)CC4C6=COC(=O)C=C6)C)O)O
Isomeric SMILES	C[C@]12CC[C@@H](C[C@]1(CC[C@@H]3[C@@H]2CC[C@]4([C@]35[C@H](O5)C[C@@H]4C6=COC(=O)C=C6)C)O)O
Alternate CAS	470-42-8
PubChem CID	11969465
NSC Number	234205
MeSH Entry Terms	marinobufagenin;marinobufogenin
Molecular Weight	400.51

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Chemical and Physical Properties

Solubility	DMSO : 100 mg/mL (249.68 mM; Need ultrasonic)
Molecular Weight	400.500 g/mol
XLogP3	2.500
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	1
Exact Mass	400.225 Da
Monoisotopic Mass	400.225 Da
Topological Polar Surface Area	79.300 Å²
Heavy Atom Count	29
Formal Charge	0
Complexity	833.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	9
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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