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m-PEG2-azide - 95%, high purity , CAS No.215181-61-6

    Grade & Purity:
  • ≥95%
In stock
Item Number
M412720
Grouped product items
SKU Size
Availability
Price Qty
M412720-50mg
50mg
2
$21.90
M412720-100mg
100mg
2
$34.90
M412720-250mg
250mg
1
$69.90
M412720-1g
1g
1
$229.90

PROTAC Linker

Basic Description

Synonyms BT-0134 | m-PEG-azide, MW 30,000 | 1-azido-2-(2-methoxyethoxy)ethane | 1-Azido-2-(2-methoxy-ethoxy)-ethane | BP-20988 | BP-23444 | DTXSID201212327 | BP-28678 | HY-130578 | Methoxypolyethylene glycol azide, (mPEG), M.W. 550 | OXDZFVNIVMSPEG-UHFFFAOYSA-N |
Specifications & Purity ≥95%
Biochemical and Physiological Mechanisms m-PEG2-azide is a PEG-based PROTAC linker that is applicable to the synthesis of PROTACs.
Storage Temp Protected from light,Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Product Description

m-PEG2-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG2-azide is a click chemistry reagent, itcontains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups. 

Application:

Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Organic 1,3-dipolar compounds
Class Allyl-type 1,3-dipolar organic compounds
Subclass Azo imides
Intermediate Tree Nodes Not available
Direct Parent Azo imides
Alternative Parents Azo compounds  Dialkyl ethers  Organic salts  Hydrocarbon derivatives  Organic cations  
Molecular Framework Aliphatic acyclic compounds
Substituents Azo imide - Azo compound - Ether - Dialkyl ether - Organic nitrogen compound - Organic oxygen compound - Hydrocarbon derivative - Organic salt - Organooxygen compound - Organonitrogen compound - Organic cation - Aliphatic acyclic compound
Description This compound belongs to the class of organic compounds known as azo imides. These are n-Imides of azo compounds, analogous to azoxy compounds, having a delocalized structure.
External Descriptors Not available

Names and Identifiers

IUPAC Name 1-azido-2-(2-methoxyethoxy)ethane
INCHI InChI=1S/C5H11N3O2/c1-9-4-5-10-3-2-7-8-6/h2-5H2,1H3
InChIKey OXDZFVNIVMSPEG-UHFFFAOYSA-N
Smiles COCCOCCN=[N+]=[N-]
Isomeric SMILES COCCOCCN=[N+]=[N-]
Molecular Weight 145.16
Reaxy-Rn 6918271
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=6918271&ln=

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

8 results found

Lot Number Certificate Type Date Item
B2426351 Certificate of Analysis Jan 04, 2024 M412720
B2426352 Certificate of Analysis Jan 04, 2024 M412720
B2426353 Certificate of Analysis Jan 04, 2024 M412720
B2426354 Certificate of Analysis Jan 04, 2024 M412720
B2426355 Certificate of Analysis Jan 04, 2024 M412720
B2426356 Certificate of Analysis Jan 04, 2024 M412720
B2426357 Certificate of Analysis Jan 04, 2024 M412720
B2426358 Certificate of Analysis Jan 04, 2024 M412720

Chemical and Physical Properties

Solubility Solubility (25°C) In vitro      
Sensitivity Light sensitive
Molecular Weight 145.160 g/mol
XLogP3 0.800
Hydrogen Bond Donor Count 0
Hydrogen Bond Acceptor Count 4
Rotatable Bond Count 6
Exact Mass 145.085 Da
Monoisotopic Mass 145.085 Da
Topological Polar Surface Area 32.800 Ų
Heavy Atom Count 10
Formal Charge 0
Complexity 111.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 1

Citations of This Product

1. Qiuxia Wu, Xinran Sun, Zhenming Yang, Pengfei Shi, Huacheng Zhang, Jie Han.  (2023)  Synthesis, Optical Properties and Cellular Toxicity of Water-Soluble near Infrared-II Fluorescent Assemblies Based on Pillar[5]arene.  Polymers,  15  (18): (3853). 

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