Determine the necessary mass, volume, or concentration for preparing a solution.
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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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M412720-50mg
|
50mg |
2
|
$21.90
|
|
|
M412720-100mg
|
100mg |
2
|
$34.90
|
|
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M412720-250mg
|
250mg |
1
|
$69.90
|
|
|
M412720-1g
|
1g |
1
|
$229.90
|
|
PROTAC Linker
| Synonyms | BT-0134 | m-PEG-azide, MW 30,000 | 1-azido-2-(2-methoxyethoxy)ethane | 1-Azido-2-(2-methoxy-ethoxy)-ethane | BP-20988 | BP-23444 | DTXSID201212327 | BP-28678 | HY-130578 | Methoxypolyethylene glycol azide, (mPEG), M.W. 550 | OXDZFVNIVMSPEG-UHFFFAOYSA-N | |
|---|---|
| Specifications & Purity | ≥95% |
| Biochemical and Physiological Mechanisms | m-PEG2-azide is a PEG-based PROTAC linker that is applicable to the synthesis of PROTACs. |
| Storage Temp | Protected from light,Store at -20°C |
| Shipped In |
Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available. |
| Product Description |
m-PEG2-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG2-azide is a click chemistry reagent, itcontains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups. Application: Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. |
Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organic 1,3-dipolar compounds |
| Class | Allyl-type 1,3-dipolar organic compounds |
| Subclass | Azo imides |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Azo imides |
| Alternative Parents | Azo compounds Dialkyl ethers Organic salts Hydrocarbon derivatives Organic cations |
| Molecular Framework | Aliphatic acyclic compounds |
| Substituents | Azo imide - Azo compound - Ether - Dialkyl ether - Organic nitrogen compound - Organic oxygen compound - Hydrocarbon derivative - Organic salt - Organooxygen compound - Organonitrogen compound - Organic cation - Aliphatic acyclic compound |
| Description | This compound belongs to the class of organic compounds known as azo imides. These are n-Imides of azo compounds, analogous to azoxy compounds, having a delocalized structure. |
| External Descriptors | Not available |
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| IUPAC Name | 1-azido-2-(2-methoxyethoxy)ethane |
|---|---|
| INCHI | InChI=1S/C5H11N3O2/c1-9-4-5-10-3-2-7-8-6/h2-5H2,1H3 |
| InChIKey | OXDZFVNIVMSPEG-UHFFFAOYSA-N |
| Smiles | COCCOCCN=[N+]=[N-] |
| Isomeric SMILES | COCCOCCN=[N+]=[N-] |
| Molecular Weight | 145.16 |
| Reaxy-Rn | 6918271 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=6918271&ln= |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Jan 04, 2024 | M412720 | |
| Certificate of Analysis | Jan 04, 2024 | M412720 | |
| Certificate of Analysis | Jan 04, 2024 | M412720 | |
| Certificate of Analysis | Jan 04, 2024 | M412720 | |
| Certificate of Analysis | Jan 04, 2024 | M412720 | |
| Certificate of Analysis | Jan 04, 2024 | M412720 | |
| Certificate of Analysis | Jan 04, 2024 | M412720 | |
| Certificate of Analysis | Jan 04, 2024 | M412720 |
| Solubility | Solubility (25°C) In vitro |
|---|---|
| Sensitivity | Light sensitive |
| Molecular Weight | 145.160 g/mol |
| XLogP3 | 0.800 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 6 |
| Exact Mass | 145.085 Da |
| Monoisotopic Mass | 145.085 Da |
| Topological Polar Surface Area | 32.800 Ų |
| Heavy Atom Count | 10 |
| Formal Charge | 0 |
| Complexity | 111.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Qiuxia Wu, Xinran Sun, Zhenming Yang, Pengfei Shi, Huacheng Zhang, Jie Han. (2023) Synthesis, Optical Properties and Cellular Toxicity of Water-Soluble near Infrared-II Fluorescent Assemblies Based on Pillar[5]arene. Polymers, 15 (18): (3853). |