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Lys-CoA, Inhibitor of E1A binding protein p300;Inhibitor of lysine acetyltransferase 2B, CAS No.rp174483, Inhibitor of E1A binding protein p300;Inhibitor of lysine acetyltransferase 2B

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Item Number
rp174483
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rp174483-500μg
500μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,334.90
rp174483-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,334.90

Basic Description

Product Name Lys-CoA, Inhibitor of E1A binding protein p300;Inhibitor of lysine acetyltransferase 2B, CAS No.rp174483
Synonyms Ac-Lys(CoA)-NH2
Grade Moligand™
Specifications & Purity Moligand™
Action Type INHIBITOR
Mechanism of action Inhibitor of E1A binding protein p300;Inhibitor of lysine acetyltransferase 2B

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Lipids and lipid-like molecules
Class S-alkyl-CoAs
Subclass Not available
Intermediate Tree Nodes Not available
Direct Parent S-alkyl-CoAs
Alternative Parents Coenzyme A and derivatives  Purine ribonucleoside diphosphates  Ribonucleoside 3'-phosphates  Pentose phosphates  N-acyl-alpha amino acids and derivatives  Beta amino acids and derivatives  Glycosylamines  6-aminopurines  Monosaccharide phosphates  Organic pyrophosphates  Aminopyrimidines and derivatives  Monoalkyl phosphates  Imidolactams  N-acyl amines  N-substituted imidazoles  Oxolanes  Heteroaromatic compounds  Acetamides  Primary carboxylic acid amides  Secondary alcohols  Secondary carboxylic acid amides  Oxacyclic compounds  Sulfenyl compounds  Dialkylthioethers  Azacyclic compounds  Hydrocarbon derivatives  Primary amines  Carbonyl compounds  Organic oxides  
Molecular Framework Aromatic heteropolycyclic compounds
Substituents Coenzyme a or derivatives - Purine ribonucleoside 3',5'-bisphosphate - Purine ribonucleoside bisphosphate - Purine ribonucleoside diphosphate - Ribonucleoside 3'-phosphate - Pentose phosphate - Pentose-5-phosphate - N-acyl-alpha amino acid or derivatives - Beta amino acid or derivatives - Glycosyl compound - N-glycosyl compound - Organic pyrophosphate - Pentose monosaccharide - Monosaccharide phosphate - N-substituted-alpha-amino acid - Alpha-amino acid or derivatives - 6-aminopurine - Imidazopyrimidine - Purine - Monoalkyl phosphate - Aminopyrimidine - Pyrimidine - Organic phosphoric acid derivative - Alkyl phosphate - Imidolactam - Monosaccharide - N-acyl-amine - Phosphoric acid ester - Fatty acyl - N-substituted imidazole - Fatty amide - Acetamide - Azole - Imidazole - Heteroaromatic compound - Oxolane - Amino acid or derivatives - Secondary carboxylic acid amide - Carboxamide group - Primary carboxylic acid amide - Secondary alcohol - Thioether - Dialkylthioether - Carboxylic acid derivative - Sulfenyl compound - Azacycle - Organoheterocyclic compound - Oxacycle - Primary amine - Carbonyl group - Organic oxygen compound - Organooxygen compound - Organonitrogen compound - Organic nitrogen compound - Amine - Alcohol - Organic oxide - Hydrocarbon derivative - Organosulfur compound - Aromatic heteropolycyclic compound
Description This compound belongs to the class of organic compounds known as s-alkyl-coas. These are alkyl sulfides consisting of coenzyme A that carries an S-alkyl substituent.
External Descriptors Not available

Associated Targets(Human)

EP300 Tchem Histone acetyltransferase p300 (9 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
KAT2B Tchem Histone acetyltransferase KAT2B (1 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
EP300 Tchem Histone acetyltransferase p300 (1259 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
KAT2B Tchem Histone acetyltransferase PCAF (884 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
KAT5 Tchem Histone acetyltransferase KAT5 (85 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Storage and Shipping

CAS rp174483

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Genetic information

Alternate Names Ac-Lys(CoA)-NH2
Reference
  • 1. Kinetics and inhibition of recombinant human cystathionine gamma-lyase. Toward the rational control of transsulfuration., The Journal of biological chemistry, Steegborn, C C and 7 more authors.
  • 2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences., Proceedings of the National Academy of Sciences of the United States of America, Strausberg, Robert L RL and 83 more authors.
  • 3. Genomic basis of cystathioninuria (MIM 219500) revealed by multiple mutations in cystathionine gamma-lyase (CTH)., Human genetics, Wang, Jian J and Hegele, Robert A RA.
  • 4. Cloning and nucleotide sequence of human liver cDNA encoding for cystathionine gamma-lyase., Biochemical and biophysical research communications, Lu, Y Y, O'Dowd, B F BF, Orrego, H H and Israel, Y Y.
  • 5. Single nucleotide polymorphism in CTH associated with variation in plasma homocysteine concentration., Clinical genetics, Wang, J J, Huff, A M AM, Spence, J D JD and Hegele, R A RA.
  • 6. Cystathionine gamma-lyase overexpression inhibits cell proliferation via a H2S-dependent modulation of ERK1/2 phosphorylation and p21Cip/WAK-1., The Journal of biological chemistry, Yang, Guangdong G, Cao, Kun K, Wu, Lingyun L and Wang, Rui R.
  • 7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)., Genome research, Gerhard, Daniela S DS and 115 more authors.
  • 8. Towards a proteome-scale map of the human protein-protein interaction network., Nature, Rual, Jean-François JF and 37 more authors.
  • 9. The DNA sequence and biological annotation of human chromosome 1., Nature, Gregory, S G SG and 178 more authors.
  • 10. Polymorphisms in one-carbon metabolism and trans-sulfuration pathway genes and susceptibility to bladder cancer., International journal of cancer, Moore, Lee E LE and 14 more authors. more

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