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G protein-coupled receptors (GPCRs)
Melatonin receptors
LY 156735 , CAS No.L611633, Agonist of MT 1 receptor;Agonist of MT 2 receptor

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LY 156735 , CAS No.L611633, Agonist of MT 1 receptor;Agonist of MT 2 receptor

COA

Grade & Purity:

Moligand™

PubChem CID: 219018

In stock

Item Number

L611633

Grouped product items
SKU	Size	Availability	Price	Qty
L611633-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$330.90
L611633-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,300.90

View related series

MT1 receptor Agonist (29) MT2 receptor Agonist (33)

Basic Description

Synonyms	HY-106136 \| N-[2-(6-Chloro-5-methoxy-1H-indol-3-yl)propyl]ethanimidic acid \| 3ZX95B1ZWK \| Q6460405 \| UNII-3ZX95B1ZWK \| DTXSID70922760 \| TIK-301 \| PD-6735 \| CS-0024957 \| LY 156735 \| n-[(2r)-2-(6-chloro-5-methoxy-1h-indol-3-yl)propyl]acetamide \| PD-6735;LY-
Specifications & Purity	Moligand™
Grade	Moligand™
Action Type	AGONIST
Mechanism of action	Agonist of MT 1 receptor;Agonist of MT 2 receptor

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
  - Class Indoles and derivatives
    - Subclass Indoles

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
Class	Indoles and derivatives
Subclass	Indoles
Intermediate Tree Nodes	Not available
Direct Parent	Indoles
Alternative Parents	Anisoles Alkyl aryl ethers Pyrrolines Pyrroles Heteroaromatic compounds Acetamides Amino acids and derivatives Vinyl chlorides Dialkylamines Chloroalkenes Azacyclic compounds Organopnictogen compounds Organochlorides Organic oxides Hydrocarbon derivatives
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	Indole - Anisole - Alkyl aryl ether - Benzenoid - Heteroaromatic compound - Acetamide - Pyrroline - Pyrrole - Carboxamide group - Amino acid or derivatives - Azacycle - Chloroalkene - Haloalkene - Vinyl halide - Vinyl chloride - Secondary amine - Ether - Secondary aliphatic amine - Carboxylic acid derivative - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Organochloride - Organohalogen compound - Amine - Aromatic heteropolycyclic compound
Description	This compound belongs to the class of organic compounds known as indoles. These are compounds containing an indole moiety, which consists of pyrrole ring fused to benzene to form 2,3-benzopyrrole.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

MTNR1A Tclin Melatonin receptor type 1A (2 Activities)

Discover Target: MTNR1A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MTNR1B Tclin Melatonin receptor type 1B (2 Activities)

Discover Target: MTNR1B

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Associated Targets(non-human)

Melatonin receptor 1B (19 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	N-[(2R)-2-(6-chloro-5-methoxy-1H-indol-3-yl)propyl]acetamide
INCHI	InChI=1S/C14H17ClN2O2/c1-8(6-16-9(2)18)11-7-17-13-5-12(15)14(19-3)4-10(11)13/h4-5,7-8,17H,6H2,1-3H3,(H,16,18)/t8-/m0/s1
InChIKey	RKHCTAKUYDTFHE-QMMMGPOBSA-N
Smiles	COc1cc2c(cc1Cl)[nH]cc2[C@H](CNC(=O)C)C
Isomeric SMILES	C[C@@H](CNC(=O)C)C1=CNC2=CC(=C(C=C21)OC)Cl
PubChem CID	219018

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Chemical and Physical Properties

Molecular Weight	280.750 g/mol
XLogP3	2.600
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	4
Exact Mass	280.098 Da
Monoisotopic Mass	280.098 Da
Topological Polar Surface Area	54.100 Å²
Heavy Atom Count	19
Formal Charge	0
Complexity	327.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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