Diverse loss mechanism enhanced microwave thermal effects of capacitor-like structure Ti3C2Tx MXene/CNT for rapid treatment of osteomyelitis

Compared to phototherapy, microwave therapy has emerged as a promising approach for the treatment of deeply tissue-infected osteomyelitis owing to deep penetration ability, precise positioning heating, low damage to normal tissue. However, it is still significant to design materials with efficient microwave thermal conversion. In this paper, capacitor-like structure Ti 3 C 2 T x MXene/CNT is prepared to achieve high microwave thermal conversion efficiencies for safe and efficient microwave therapy through mechanisms associated with polarization and induced electric fields. Ti 3 C 2 T x MXene/CNT have been shown to achieve significant microwave thermal effects at varying thicknesses of tissue barrier and can rapidly increase the temperature in a short period of time, effectively causing 98.80% eradication of Staphylococcus aureus and 99.24% eradication of Escherichia coli within 20 min. Combined with remarkable antimicrobial effect and acceptable biocompatibility, this may provide reference for the safe and effective microwave therapy strategies to treat osteomyelitis.