A Non-Enzymatic Electrochemical Sensor Based on Cerium Oxide Nanocubes for the Rapid Detection of Hydrogen Peroxide Residues in Food Samples†

The rapid and simple detection methods of hydrogen peroxide (H 2 O 2 ) residues is highly required for food safety. Herein, an electrochemical H 2 O 2 sensor is developed with cerium oxide nanocubes as highly active non-enzymatic catalyst. Combined with carbon black to improve conductivity, the disposable sensor can determine H 2 O 2 in the range from 100 to 100 μM with a limit of detection (LOD) of 100 nM. This sensor also shows good selectivity and reproducibility, which is enabled to detect H 2 O 2 in real food samples without any pretreatment in 100 s, providing a new solution for the direct quantitative measurement of H 2 O 2 residues for food safety. © 2024 Institute of Electrical Engineers of Japan and Wiley Periodicals LLC.