A fluorescence sensor for the detection of zearalenone based on magnetic molecular imprinted polymers and carbon dots

Zearalenone (ZEN) poses a threat by infiltrating the food chain and triggering various diseases; hence, the precise detection of ZEN is essential for ensuring food safety. Herein, a fluorescence sensor was constructed for sensitive and selective detection of ZEN based on magnetic molecular imprinted polymers (MIPs/Fe 3 O 4 @SiO 2 ) and carbon dots (CDs). MIPs/Fe 3 O 4 @SiO 2 , serving as recognition elements, captured ZEN in real samples. Using a magnet, we separated the MIPs/Fe 3 O 4 @SiO 2 that had captured ZEN and added them to a specific volume of the CDs solution, resulting in fluorescence quenching of the CDs. As the CDs were not directly exposed to the sample solution, these fluorescence probes exhibit a satisfactory level of anti-interference performance. Under optimal experimental conditions, an increase in ZEN concentration results in a linear decrease in the fluorescence intensity of the CDs. The sensor has a linear response range of 0.5–30 ng mL −1 with the limit of detection as low as 0.14 ng mL −1 (LOD = 3 σ/s). Furthermore, this developed sensor demonstrated high selectivity, sensitivity, and stability. This sensor has good application potential in the analysis of ZEN in complicated samples.