Synthesization of flexible SERS imprinted sensor based on Ag/GO composites and selective detection of antibiotic in aqueous sample

In this study, it presents a novel surface-enhanced Raman scattering (SERS) imprinted membrane to be applied into the detection of trace-level antibiotic in aqueous samples. Graphene oxide- argentum (GO/Ag) composites are chosen as the SERS substrates to fabricate on poly(vinylidene fluoride) (PVDF) membrane surface, increasing the hydrophilia and promoting the sensitivity. The amount of GO is investigated to confirm the optimal concentration. Whereafter, in order to effectively apply into practical sample detection, the technique of molecular imprinting is also introduced to improve the selectivity of SERS membrane. The SERS imprinted membrane (AGP-MIM) is synthesized by the process of two-step precipitation polymerization and applied into the detection of enrofloxacin hydrochloride. The characteristics are adequately investigated and proved that the AGP-MIM can be applied into practical samples detection.