Ammonia Modified MXene/Aniline Copolymers Electrochemical Sensors for Ultrasensitive Sensing Glutathione

Graphical Biosensors Based on MXene Composite : A novel ammonia modified MXene/aniline copolymer (PTA) was prepared via electropolymerization with the rose-like N-Ti 3 C 2 T x and aniline. PTA has a network structure and excellent electrochemical performance. Fabricated PTA/GCE sensor has been used to detect GSH with high stability and sensitivity, and it was applied for rapidly detect GSH in real samples with excellent recoveries. Herein, unique ammonia modified MXene/aniline copolymers (PTA) are prepared by facile and green electropolymerization with the rose-like ammonia modified MXene (N-Ti 3 C 2 T x ) and aniline to modify electrochemical sensor to detect GSH with high performance. Scanning electron microscopy (SEM), cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), and differential pulse voltammetry (DPV) characterizations show that the PTA copolymer exhibits a net-like structure and excellent electrochemical performance. It displays that the PTA can be regarded as an outstanding electrode nanomaterial for high-performance sensors. Moreover, the PTA/GCE biosensor is fabricated through one-step electropolymerization method for detecting glutathione. Under the optimum conditions, the limit of detection of the biosensor is calculated to be 5.21×10 −14 mol L −1 with a high sensitivity of 32.9 μA nmol −1 L cm −2 . At the same time, the biosensor displays excellent selectivity and stability. Furthermore, the fabricated PTA/GCE biosensor is applied to detect glutathione of plasma samples with good recoveries, indicating that the sensor has broad application prospects in the field of biological and medical analysis.