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Synthesis of Silver Nanoparticles Using Lysozyme for Scald-Wound Healing

ACS Applied Nano Materials [2023]
Liang-Liang Chen, Wen-Pu Shi, Tuo-Di Zhang, Wen-Juan Lin, Ya-Qing Zhou, Xiao-Qian Jin, Huan Liang, Wei-Hong Guo, Da-Chuan Yin
ABSTRACT

The use of natural proteins is a green and effective method for synthesizing silver nanoparticles (AgNPs). Aromatic amino acids of proteins play a reducing role in synthesis, and proteins are coated on the surface of AgNPs to play the role of stabilizers. In this study, we developed an efficient one-step method for synthesizing AgNPs using lysozyme (LYZ) under visible-light irradiation from a xenon lamp in situ. The light conditions and LYZ structure could substantially affect the synthesis. Antibacterial and scald-wound healing results showed that LYZ/AgNPs had broad-spectrum and efficient antibacterial activity and promoted scald-wound healing. Therefore, the proposed synthesis method and LYZ/AgNPs have good practical application prospects.

MATERIALS

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