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| SKU | Size | Availability |
Price | Qty |
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L386714-5mg
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5mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$85.90
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L386714-10mg
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10mg |
5
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$136.90
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L386714-25mg
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25mg |
1
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$289.90
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a component of the cell wall of Gram-negative bacteria and Specific activator of Toll-like receptor (TLR) 4.
| Synonyms | LPS |
|---|---|
| Specifications & Purity | purified by trichloroacetic acid extraction |
| Biochemical and Physiological Mechanisms | Physiol Actions:Lipopolysaccharides (LPS) are localized in the outer layer of the membrane and are, in noncapsulated strains, exposed on the cell surface. They contribute to the integrity of the outer membrane, and protect the cell against the action of b |
| Storage Temp | Store at 2-8°C |
| Shipped In |
Wet ice This product requires cold chain shipping. Ground and other economy services are not available. |
| Product Description |
Lipopolysaccharide,|E. coli|O55:B5 is a component of the cell wall of the O55:B5 serotype of the Gram-negative bacteria,|Escherichia coli|. Lipopolysaccharides (LPS) are made up of a hydrophobic lipid, a hydrophilic core polysaccharide chain and a hydrophilic O-antigenic polysaccharide side chain. LPS molecules contribute to the outer integrity of the cell membrane, protect the cell against bile salts and lipophilic antibiotics, and act as endotoxins in animals. LPS induces a strong immune response by binding to the CD14/TLR4/MD2 receptor complex, which promotes the secretion of pro-inflammatory cytokines. LPS is also an exogenous pyrogen. LPS O55:B5 has been derived from a serotype of|E. coli|O55:B5, which is part of a subdivision based on the O antigen component of LPS. Lipopolysaccharide, E. coli O55:B5 is a form of lipopolysaccharide (LPS) extracted from wild-type S-form E. coli serotype O55:B5. Lipopolysaccharide, E. coli O55:B5 is commonly used to activate toll-like receptor 4 (TLR4) on leukocytes, eliciting inflammatory signaling in isolated cells and in vivo.1,2,3,4 Lipopolysaccharide, E. coli O55:B5 includes three regions, the O-antigenic polysaccharide chain, the core oligosaccharide, and lipid A. Lipopolysaccharide, E. coli O55:B5 stimulates the activity of inducible nitric oxide synthase. Lipopolysaccharide, E. coli O55:B5 induces apoptosis in mouse thymus and swine lymphocytes. Lipopolysaccharide, E. coli O55:B5 is also known as LPS. Lipopolysaccharide, E. coli O55:B5is a component of the cell wall of Gram-negative bacteria and Specific activator of Toll-like receptor (TLR) 4. Usage: The product is soluble in water (5 mg/ml) or cell culture medium (1 mg/ml) yielding a hazy, faint yellow solution. A more concentrated, though still hazy, solution (20 mg/ml) has been achieved in aqueous saline after vortexing and warming to 70-80 oC. Lipopolysaccharides are molecules that form micelles in every solvent. Hazy solutions are observed in water and phosphate buffered saline. Organic solvents do not give clearer solutions. Methanol yields a turbid suspension with floaters, while water yields a homogeneously hazy solution. |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Apr 18, 2025 | L386714 | |
| Certificate of Analysis | Apr 18, 2025 | L386714 | |
| Certificate of Analysis | Apr 18, 2025 | L386714 | |
| Certificate of Analysis | Dec 12, 2024 | L386714 | |
| Certificate of Analysis | Dec 12, 2024 | L386714 | |
| Certificate of Analysis | Dec 12, 2024 | L386714 | |
| Certificate of Analysis | Dec 12, 2024 | L386714 | |
| Certificate of Analysis | Apr 18, 2024 | L386714 | |
| Certificate of Analysis | Apr 18, 2024 | L386714 | |
| Certificate of Analysis | Mar 09, 2024 | L386714 | |
| Certificate of Analysis | Dec 01, 2023 | L386714 | |
| Certificate of Analysis | Dec 01, 2023 | L386714 | |
| Certificate of Analysis | Dec 01, 2023 | L386714 | |
| Certificate of Analysis | Dec 01, 2023 | L386714 | |
| Certificate of Analysis | Dec 01, 2023 | L386714 | |
| Certificate of Analysis | May 17, 2023 | L386714 | |
| Certificate of Analysis | May 17, 2023 | L386714 | |
| Certificate of Analysis | May 17, 2023 | L386714 | |
| Certificate of Analysis | May 17, 2023 | L386714 | |
| Certificate of Analysis | Sep 27, 2022 | L386714 | |
| Certificate of Analysis | Sep 27, 2022 | L386714 | |
| Certificate of Analysis | Sep 27, 2022 | L386714 | |
| Certificate of Analysis | Sep 27, 2022 | L386714 | |
| Certificate of Analysis | Jul 30, 2022 | L386714 | |
| Certificate of Analysis | Jul 30, 2022 | L386714 | |
| Certificate of Analysis | Jul 30, 2022 | L386714 |
| Solubility | Soluble in water (5 mg/ml). |
|---|
Starting at $109.90
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