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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab183059-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$79.90
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Ab183059-1mg
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1mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$389.90
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Ab183059-5mg
|
5mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$669.90
|
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Ab183059-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,069.90
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Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level< 0.01EU/μg; Human IgG1; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated
| Product Name | Sontuzumab (anti-MUC1) - Primary antibody, specific to MUC1, Human IgG1, OTHER of Mucin-1 other |
|---|---|
| Synonyms | ADMCKD antibody | ADMCKD1 antibody | Breast carcinoma associated antigen DF3 antibody | Breast carcinoma-associated antigen DF3 antibody | CA 15-3 antibody | CA15 3 antibody | CA15 3 antigen antibody | CA15-3 antibody | CA15.3 antibody | Cancer antigen 15 |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Biochemical and Physiological Mechanisms | The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. The beta subunit contains a C-terminal domain which is involv |
| Host species | Human |
| Specificity | MUC1 |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | OTHER |
| Mechanism of action | OTHER of Mucin-1 other |
| Product Description |
Sontuzumab (anti-MUC1) is a humanizedised IgG1κ MUC1 specific monoclonal antibody. Sontuzumab (anti-MUC1) binds the extracellular MUC1 peptide sequence PDTR with a Kd of ~1 nM. Sontuzumab (anti-MUC1) can be used for the research of breast cancer.
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| Isotype | Human IgG1 |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 147.16 kDa |
| Purification Method | Protein A purified |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 372075-37-1 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Sontuzumab (anti-MUC1) (Ab183059) - Flow Cytometry
Flow Cytometry analysis of MDA-MB-415 cells labelling MUC1 with Sontuzumab (anti-MUC1) (Ab183059) at 1×105 cell/well.
Sontuzumab (anti-MUC1) (Ab183059) - SEC
The purity of Sontuzumab (anti-MUC1) (Ab183059) is more than 95% verified by HPLC.
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