Grouped product items
SKU	Size	Availability	Price
Ab183323-100μg	100μg	10	$189.90
Ab183323-1mg	1mg	4	$919.90
Ab183323-5mg	5mg	1	$2,299.90
Ab183323-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$3,679.90

Purity≥90% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Conjugated (MC-VC-PAB-MMAE)

View related series

Click to view target information: CD22

Accession#:P20273 (13) CD22 (15) Cell Cycle (2830) Gene ID:933 (14) MC-VC-PAB-MMAE (18) SIGLEC2 (8)

Basic Description

Product Name	Pinatuzumab vedotin (anti-CD22) - Primary antibody, specific to CD22, Human IgG1, BINDING AGENT of CD22 binding agent
Synonyms	B cell receptor CD22 precursor antibody \| B lymphocyte cell adhesion molecule antibody \| B-cell receptor CD22 antibody \| B-lymphocyte cell adhesion molecule antibody \| BL CAM antibody \| BL-CAM antibody \| BLCAM antibody \| CD 22 antibody \| CD22 antibody \| C
Specifications & Purity	Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥90%(SDS-PAGE&SEC-HPLC), See COA
Host species	Human
Specificity	CD22
Conjugation	MC-VC-PAB-MMAE
Grade	Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type	BINDING AGENT
Mechanism of action	BINDING AGENT of CD22 binding agent
Product Description	Pinatuzumab vedotin (anti-CD22), is an antibody-drug conjugate (ADC) composed of CD22 (Sialic acid binding Ig-like lectin 2, SIGLEC2, SIGLEC-2, B-lymphocyte cell adhesion molecule, BL-CAM, Leu-14) antibody and cytotoxic agent monomethyl auristatin E (MMAE) conjugated through maleimidocaproyl-valyl-citrullinyl-p-aminobenzyloxycarbonyl (mc-val-cit-PABC) type linker. Purity ≥90% (SDS-PAGE&SEC) Endotoxin Level < 1.0EU/mg

Product Properties

Isotype	Human IgG1
Light Chain Type	kappa
SDS-PAGE	151.97 kDa
Purification Method	Protein A purified
Shape	Liquid
Concentration	See COA
Storage Temp	Store at -80°C,Avoid repeated freezing and thawing
Shipped In	Ice chest + Ice pads
Stability And Storage	Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS	1313706-14-7

Associated Targets(Human)

CD22 Tclin B-cell receptor CD22 (0 Activities)

Discover Target: CD22

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Images

Flow Cytometry: Pinatuzumab vedotin (anti-CD22) (Ab183323)

Pinatuzumab vedotin (anti-CD22) (Ab183323) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD22 with Pinatuzumab vedotin (anti-CD22) (Ab183323) conjugated with biotin (right panel) compared with Human IgG (Biotin) (Ab180314) - Isotype Control (left panel) and detected with SA-PE (rp156150).

Flow Cytometry: Pinatuzumab vedotin (anti-CD22) (Ab183323)

Pinatuzumab vedotin (anti-CD22) (Ab183323) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD22 (red) with Pinatuzumab vedotin (anti-CD22) (Ab183323) conjugated with biotin and detected with SA-PE (rp156150). Blue - Isotype control, Human IgG (Biotin) (Ab180314). Black - Unlabelled control, cells without incubation with primary antibody.

Flow Cytometry: Pinatuzumab vedotin (anti-CD22) (Ab183323)

Pinatuzumab vedotin (anti-CD22) (Ab183323) - Flow Cytometry
Flow Cytometry analysis of Raji cells labelling CD22 (red) with Pinatuzumab vedotin (anti-CD22) (Ab183323). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

ELISA: Pinatuzumab vedotin (anti-CD22) (Ab183323)

Pinatuzumab vedotin (anti-CD22) (Ab183323) - ELISA
Immobilized Recombinant Human Siglec-2/CD22 protein (rp169575) at 1.0 μg/mL can bind Pinatuzumab vedotin (anti-CD22) (Ab183323) with the EC50 of 73.42 ng/mL.

SEC: Pinatuzumab vedotin (anti-CD22) (Ab183323)

Pinatuzumab vedotin (anti-CD22) (Ab183323) - SEC
The purity of Pinatuzumab vedotin (anti-CD22) (Ab183323) is more than 95% verified by HPLC.

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number	Certificate Type	Date	Item
ZJ24F0708979	Certificate of Analysis	Jul 31, 2024	Ab183323
ZJ24F0708978	Certificate of Analysis	Jul 31, 2024	Ab183323
ZJ24F0708977	Certificate of Analysis	Jul 31, 2024	Ab183323

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Pinatuzumab vedotin (anti-CD22) - Primary antibody, specific to CD22, Human IgG1, BINDING AGENT of CD22 binding agent, BINDING AGENT of CD22 binding agent

Basic Description

Product Properties

Associated Targets(Human)

Mechanisms of Action

Images

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

Solution Calculators

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

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