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Iladatuzumab vedotin (anti-CD79b) - Primary antibody, specific to CD79B, Purity>90% (SDS-PAGE&SEC), high purity, Human IgG1

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human
  • Isotype: Human IgG1
  • Conjugation: MC-VC-PAB-MMAE
In stock
Item Number
Ab183320
Grouped product items
SKU Size
Availability
Price Qty
Ab183320-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$189.90
Ab183320-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$919.90
Ab183320-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,299.90
Ab183320-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$3,679.90

Purity>90% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Conjugated (MC-VC-PAB-MMAE)

Basic Description

Product Name Iladatuzumab vedotin (anti-CD79b) - Primary antibody, specific to CD79B, Purity>90% (SDS-PAGE&SEC), high purity, Human IgG1
Synonyms AGM6 antibody | B cell antigen receptor complex associated protein beta chain antibody | B cell specific glycoprotein B29 antibody | B-cell antigen receptor complex-associated protein beta chain antibody | B-cell-specific glycoprotein B29 antibody | B29 a
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥90%(SDS-PAGE&SEC-HPLC), See COA
Biochemical and Physiological Mechanisms Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances pho
Host species Human
Specificity CD79B
Conjugation MC-VC-PAB-MMAE
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Product Description

Iladatuzumab vedotin (anti-CD79b), is an antibody-drug conjugate (ADC) composed of CD79B (immunoglobulin-associated CD79 beta) antibody and cytotoxic agent monomethyl auristatin E (MMAE) conjugated through maleimidocaproyl-valyl-citrullinyl-p-aminobenzyloxycarbonyl (mc-val-cit-PABC) type linker. Iladatuzumab vedotin (anti-CD79b) has the potential for B-cell non-Hodgkin lymphoma (B-NHL) research.


Product Properties

Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 145 kDa
Purification Method Protein A purified
Purity Purity>90% (SDS-PAGE&SEC)
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 1906205-77-3

Associated Targets(Human)

CD79B Tclin B-cell antigen receptor complex-associated protein beta chain (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Iladatuzumab vedotin (anti-CD79b) (Ab183320) - ELISA
Immobilized Recombinant Human CD79B protein (rp176729) at 1.0 μg/mL can bind Iladatuzumab vedotin (anti-CD79b) (Ab183320) with the EC50 of 47.25 ng/mL.

Iladatuzumab vedotin (anti-CD79b) (Ab183320) - SEC
The purity of Iladatuzumab vedotin (anti-CD79b) (Ab183320) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Solution Calculators

Reviews

Customer Reviews

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