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Lidocaine Hydrochloride Monohydrate - ≥98%, high purity , Sodium channel alpha subunit blocker, CAS No.6108-05-0, Sodium channel alpha subunit blocker

2 Citations

COA

Grade & Purity:

Moligand™

≥98%

Cas Number: 6108-05-0
Molecular Weight: 288.81
MDL number: MFCD00150329
PubChem CID: 16219577
PubChem SID: 504768403

In stock

Item Number

L137296

Grouped product items
SKU	Size	Availability	Price
L137296-5g	5g	3	$24.90
L137296-25g	25g	3	$79.90
L137296-100g	100g	3	$199.90
L137296-500g	500g	3	$649.90

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Basic Description

Synonyms	2',6'-ACETOXYLIDIDE, 2-(DIETHYLAMINO)-, HYDROCHLORIDE, HYDRATE \| LIDOCAINE HYDROCHLORIDE [USP-RS] \| 2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide hydrochloride hydrate \| BCP13499 \| LIDOCAINE HYDROCHLORIDE [GREEN BOOK] \| LIDOCAINE HYDROCHLORIDE [VANDF]
Specifications & Purity	Moligand™, ≥98%
Biochemical and Physiological Mechanisms	Lidocaine hydrochloride monohydrate is an antiarrhythmic and local anesthetic. It is mostly metabolized in the liver by Cytochrome P450 1A to the pharmacologically-active metabolites glycinexylidide and monoethylglycinexylidide. It is known to block the f
Storage Temp	Store at 2-8°C,Protected from light
Shipped In	Wet ice This product requires cold chain shipping. Ground and other economy services are not available.
Grade	Moligand™
Action Type	BLOCKER
Mechanism of action	Sodium channel alpha subunit blocker
Product Description	A fast voltage-gated sodium channel blocker

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organic acids and derivatives
  - Class Carboxylic acids and derivatives
    - Subclass Amino acids, peptides, and analogues
      - Level5 Amino acids and derivatives
        Level6 Alpha amino acids and derivatives
        Level7 Alpha amino acid amides

Kingdom	Organic compounds
Superclass	Organic acids and derivatives
Class	Carboxylic acids and derivatives
Subclass	Amino acids, peptides, and analogues
Intermediate Tree Nodes	Amino acids and derivatives - Alpha amino acids and derivatives
Direct Parent	Alpha amino acid amides
Alternative Parents	Anilides m-Xylenes N-arylamides Trialkylamines Secondary carboxylic acid amides Organopnictogen compounds Organic zwitterions Organic oxides Organic chloride salts Hydrocarbon derivatives Carbonyl compounds
Molecular Framework	Aromatic homomonocyclic compounds
Substituents	Alpha-amino acid amide - Anilide - M-xylene - Xylene - N-arylamide - Monocyclic benzene moiety - Benzenoid - Carboxamide group - Secondary carboxylic acid amide - Tertiary amine - Tertiary aliphatic amine - Organic nitrogen compound - Organic zwitterion - Organic salt - Organic chloride salt - Hydrocarbon derivative - Organic oxide - Organooxygen compound - Organonitrogen compound - Organopnictogen compound - Carbonyl group - Organic oxygen compound - Amine - Aromatic homomonocyclic compound
Description	This compound belongs to the class of organic compounds known as alpha amino acid amides. These are amide derivatives of alpha amino acids.
External Descriptors	hydrate
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

CYP1A2 Tchem Cytochrome P450 1A2 (26471 Activities)

Discover Target: CYP1A2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Homo sapiens (32628 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CBX1 Tbio Chromobox protein homolog 1 (92434 Activities)

Discover Target: CBX1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)

Discover Target: Nfe2l2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

Pubchem Sid	504768403
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/504768403
IUPAC Name	2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide;hydrate;hydrochloride
INCHI	InChI=1S/C14H22N2O.ClH.H2O/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4;;/h7-9H,5-6,10H2,1-4H3,(H,15,17);1H;1H2
InChIKey	YECIFGHRMFEPJK-UHFFFAOYSA-N
Smiles	CCN(CC)CC(=O)NC1=C(C=CC=C1C)C.O.Cl
Isomeric SMILES	CCN(CC)CC(=O)NC1=C(C=CC=C1C)C.O.Cl
WGK Germany	3
RTECS	AN7700000
Molecular Weight	288.81
Reaxy-Rn	18845016
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=18845016&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

18 results found

Lot Number	Certificate Type	Date	Item
D2527384	Certificate of Analysis	Mar 15, 2025	L137296
D2527385	Certificate of Analysis	Mar 15, 2025	L137296
D2527386	Certificate of Analysis	Mar 15, 2025	L137296
D2527387	Certificate of Analysis	Mar 15, 2025	L137296
C2524580	Certificate of Analysis	Mar 05, 2025	L137296
A2515017	Certificate of Analysis	Jan 18, 2025	L137296
J2424756	Certificate of Analysis	Apr 10, 2024	L137296
J2424774	Certificate of Analysis	Apr 10, 2024	L137296
F2214214	Certificate of Analysis	Mar 19, 2024	L137296
J2424169	Certificate of Analysis	Mar 19, 2024	L137296
F2214212	Certificate of Analysis	Mar 19, 2024	L137296
F2214207	Certificate of Analysis	Mar 19, 2024	L137296
F2214211	Certificate of Analysis	Mar 19, 2024	L137296
J2109347	Certificate of Analysis	Jul 07, 2023	L137296
J2109457	Certificate of Analysis	Jul 07, 2023	L137296
J2109349	Certificate of Analysis	Jul 07, 2023	L137296
L1727021	Certificate of Analysis	May 12, 2023	L137296
F1511026	Certificate of Analysis	Jan 06, 2023	L137296

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Chemical and Physical Properties

Solubility	Soluble in water (50 mg/ml), chloroform, ethanol, and benzene. Insoluble in diethyl ether.
Sensitivity	Light sensitive; Moisture sensitive
Molecular Weight	288.810 g/mol
XLogP3
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	5
Exact Mass	288.16 Da
Monoisotopic Mass	288.16 Da
Topological Polar Surface Area	33.300 Å²
Heavy Atom Count	19
Formal Charge	0
Complexity	228.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	3

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Ayesha Younas, Zhuolin Dong, Ziye Hou, Muhammad Asad, Mengru Li, Nan Zhang. (2023) A chitosan/fucoidan nanoparticle-loaded pullulan microneedle patch for differential drug release to promote wound healing. CARBOHYDRATE POLYMERS, 306 (120593).
2. Leixia Mei, Haihong Yang, Weimiao Dong, Min Liu, Jun Han. (2024) Fluorinated Peptide Nanoscale Hydrogel Accelerates Wound Healing via pH and Oxygen Microenvironment Regulation. ACS Applied Nano Materials, 7 (1): (382-393).

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