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Levistilide A - 10mM in DMSO, high purity , CAS No.88182-33-6

    Grade & Purity:
  • 10mM in DMSO
In stock
Item Number
L426663
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L426663-1ml
1ml
Available within 8-12 weeks(?)
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$186.90

P-gp Modulators

Basic Description

Synonyms Levistilide A | levistolide A | 88182-33-6 | Levistolid A | (Z,Z)-Diligustilide | Diligustilide | UNII-29MRT0H4CE | 29MRT0H4CE | Z,Z'-6,6',7,3'a-Diligustilide | E,Z'-6,6',7,3'a-diligustilide | 1H-5,10c-Ethanonaphtho(1,2-c:7,8-c')difuran-3,10-dione, 1,8-dibutylidene-5,5a,6,7,
Specifications & Purity 10mM in DMSO
Biochemical and Physiological Mechanisms Levistilide A (Diligustilide), a natural compound isolated from the traditional Chinese herb Ligusticum chuanxiong Hort, is a potential P-gp modulator and used for treating cancer.
Storage Temp Store at -80°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Product Description

Information

Levistilide A Levistilide A (Diligustilide), a natural compound isolated from the traditional Chinese herb Ligusticum chuanxiong Hort , is a potential P-gp modulator and used for treating cancer.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Organoheterocyclic compounds
Class Dihydrofurans
Subclass Furanones
Intermediate Tree Nodes Not available
Direct Parent Butenolides
Alternative Parents Dicarboxylic acids and derivatives  Tetrahydrofurans  Enol esters  Enoate esters  Lactones  Oxacyclic compounds  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular Framework Aliphatic heteropolycyclic compounds
Substituents 2-furanone - Dicarboxylic acid or derivatives - Enol ester - Alpha,beta-unsaturated carboxylic ester - Enoate ester - Tetrahydrofuran - Carboxylic acid ester - Lactone - Carboxylic acid derivative - Oxacycle - Hydrocarbon derivative - Organic oxide - Carbonyl group - Organic oxygen compound - Organooxygen compound - Aliphatic heteropolycyclic compound
Description This compound belongs to the class of organic compounds known as butenolides. These are dihydrofurans with a carbonyl group at the C2 carbon atom.
External Descriptors butenolide

Product Properties

ALogP 4.97
hba_count 4
Rotatable Bond 4

Names and Identifiers

IUPAC Name (1S,2S,6Z,10S,11S,16Z)-6,16-di(butylidene)-5,15-dioxapentacyclo[9.5.2.01,13.02,10.03,7]octadeca-3(7),12-diene-4,14-dione
INCHI InChI=1S/C24H28O4/c1-3-5-7-18-16-10-9-15-14-11-12-24(21(15)20(16)23(26)27-18)17(13-14)22(25)28-19(24)8-6-4-2/h7-8,13-15,21H,3-6,9-12H2,1-2H3/b18-7-,19-8-/t14-,15+,21-,24+/m1/s1
InChIKey UBBRXVRQZJSDAK-ZJHGLIIDSA-N
Smiles CCCC=C1C2=C(C3C(CC2)C4CCC35C(=C4)C(=O)OC5=CCCC)C(=O)O1
Isomeric SMILES CCC/C=C\1/C2=C([C@H]3[C@@H](CC2)[C@@H]4CC[C@@]3\5C(=C4)C(=O)O/C5=C\CCC)C(=O)O1
Molecular Weight 380.48
Reaxy-Rn 19588545
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=19588545&ln=

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Chemical and Physical Properties

DMSO(mg / mL) Max Solubility 76
DMSO(mM) Max Solubility 199.747687132044
Water(mg / mL) Max Solubility -1
Molecular Weight 380.500 g/mol
XLogP3 4.900
Hydrogen Bond Donor Count 0
Hydrogen Bond Acceptor Count 4
Rotatable Bond Count 4
Exact Mass 380.199 Da
Monoisotopic Mass 380.199 Da
Topological Polar Surface Area 52.600 Ų
Heavy Atom Count 28
Formal Charge 0
Complexity 871.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 4
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 2
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 2
Covalently-Bonded Unit Count 1

Solution Calculators

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