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Leucomalachite Green - 98%, high purity , CAS No.129-73-7

    Grade & Purity:
  • ≥98%
In stock
Item Number
L102032
Grouped product items
SKU Size
Availability
Price Qty
L102032-1g
1g
10
$25.90
L102032-5g
5g
5
$69.90
L102032-25g
25g
1
$279.90
View related series
Hematology stains (15)

Basic Description

Synonyms LeucoMalachiteGreen | Malachite green leuco base | Malachite green leuco | Leucomalachite green | 4,4'-Bis(dimethylamino)triphenylmethane | Leuco malachite green | Bis(p-dimethylaminophenyl)phenylmethane | Benzenamine,4,4'-(phenylmethylene)bis[N,N-dimethy
Specifications & Purity ≥98%
Biochemical and Physiological Mechanisms Leucomalachite green (LMG) is a chief metabolite of malachite green, a triphenylmethane dye that has been used generally as an antifungal drug in the fish industry. DNA adducts formed in livers of rats fed with leucomalachite green have been observed with
Storage Temp Store at 2-8°C,Protected from light
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Product Description

Leucomalachite Green is a triphenylmethane dye used to detect blood. A method for testing for the presence of leucomalachite green utilizing SDS-modified maghemite nanoparticles (γ-Fe(2)O(3)) has been described. Other studies have reported various protocols useful for determining the presence of Leucomalachite green in aquatic biological systems.

Application:

Leucomalachite green has been used as a reagent in presumptive tests which are used to detect invisible blood stains.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Benzenoids
Class Triphenyl compounds
Subclass Not available
Intermediate Tree Nodes Not available
Direct Parent Triphenyl compounds
Alternative Parents Dialkylarylamines  Aniline and substituted anilines  Organopnictogen compounds  Hydrocarbon derivatives  
Molecular Framework Aromatic homomonocyclic compounds
Substituents Triphenyl compound - Aniline or substituted anilines - Dialkylarylamine - Tertiary aliphatic/aromatic amine - Monocyclic benzene moiety - Tertiary amine - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Organonitrogen compound - Amine - Aromatic homomonocyclic compound
Description This compound belongs to the class of organic compounds known as triphenyl compounds. These are aromatic compounds containing a triphenyl moiety.
External Descriptors Not available

Associated Targets(Human)

NR3C1 Tclin Glucocorticoid receptor (14987 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
VDR Tclin Vitamin D receptor (26531 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PPARG Tclin Peroxisome proliferator-activated receptor gamma (15191 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
THRB Tclin Thyroid hormone receptor beta-1 (7926 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
RXRA Tclin Retinoid X receptor alpha (3637 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
NR1H4 Tclin Bile acid receptor FXR (6228 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

Pubchem Sid 488183910
Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/488183910
IUPAC Name 4-[[4-(dimethylamino)phenyl]-phenylmethyl]-N,N-dimethylaniline
INCHI InChI=1S/C23H26N2/c1-24(2)21-14-10-19(11-15-21)23(18-8-6-5-7-9-18)20-12-16-22(17-13-20)25(3)4/h5-17,23H,1-4H3
InChIKey WZKXBGJNNCGHIC-UHFFFAOYSA-N
Smiles CN(C)C1=CC=C(C=C1)C(C2=CC=CC=C2)C3=CC=C(C=C3)N(C)C
Isomeric SMILES CN(C)C1=CC=C(C=C1)C(C2=CC=CC=C2)C3=CC=C(C=C3)N(C)C
WGK Germany 3
RTECS CY1203055
UN Number 3077
Molecular Weight 330.47
Beilstein 2140506
Reaxy-Rn 2140506
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2140506&ln=

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

7 results found

Lot Number Certificate Type Date Item
G2424381 Certificate of Analysis Aug 08, 2024 L102032
E2318482 Certificate of Analysis May 24, 2023 L102032
E2318520 Certificate of Analysis May 24, 2023 L102032
E2318502 Certificate of Analysis May 24, 2023 L102032
E2318498 Certificate of Analysis May 24, 2023 L102032
E2318500 Certificate of Analysis May 24, 2023 L102032
E2318477 Certificate of Analysis May 24, 2023 L102032

Chemical and Physical Properties

Solubility Soluble in water (<0.1 mg/ml), chloroform, ethanol (4 mg/ml), and toluene.
Sensitivity Light & Air Sensitive
Melt Point(°C) 100-102°C
Molecular Weight 330.500 g/mol
XLogP3 5.300
Hydrogen Bond Donor Count 0
Hydrogen Bond Acceptor Count 2
Rotatable Bond Count 5
Exact Mass 330.21 Da
Monoisotopic Mass 330.21 Da
Topological Polar Surface Area 6.500 Ų
Heavy Atom Count 25
Formal Charge 0
Complexity 342.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 1

Citations of This Product

1. Jin Dong Cho, Hyeongmin Jin, Seongmoon Jung, Jaeman Son, Chang Heon Choi, Jong Min Park, Jin Sung Kim, Jung-in Kim.  (2023)  Development of a quasi-3D dosimeter using radiochromic plastic for patient-specific quality assurance.  MEDICAL PHYSICS,  50  (10): (6624-6636). 
2. Xiaorong Zhao, Qiulan Li, Hong Li, Yijie Wang, Feijian Xiao, Dezhi Yang, Qinghai Xia, Yaling Yang.  (2023)  SERS detection of Hg2+ and aflatoxin B1 through on–off strategy of oxidase-like Au@HgNPs/carbon dots.  FOOD CHEMISTRY,  424  (136443). 
3. Jiangru Wang, Yan Yang, Qirui Shen, Dazhong Shen, Qi Kang.  (2023)  A smartphone-based long optical path colorimetric turntable for selective determination of malachite green and investigation the specific adsorption behavior of the imprinted cavities within molecularly imprinted polymers.  MICROCHEMICAL JOURNAL,  190  (108629). 
4. Jia Wang, Chengyi Hong, Zhengzhong Lin, Zhi-Yong Huang.  (2022)  Fluorescence detection of malachite green in fish based on aptamer and SYBR Green I.  JOURNAL OF FOOD AND DRUG ANALYSIS,  30  (3): ( 369–381). 
5. Jia Wang, Chen Zhao, Chengyi Hong, Zhengzhong Lin, Zhiyong Huang.  (2021)  Rapid detection of malachite green in fish and water based on the peroxidase-like activity of Fe3O4NPs enhanced with aptamer.  JOURNAL OF FOOD COMPOSITION AND ANALYSIS,  104  (104162). 
6. Fu Guiyu, Weng Huanyuan, Lai Zhuzhi, Lin Zhengzhong, Huang Zhiyong.  (2021)  Detection of malachite green residue in aquaculture water by using a rare earth fluorescence probe.  JOURNAL OF CHEMICAL SCIENCES,  133  (2): (1-8). 
7. Jin Dong Cho, Jaeman Son, Chang Heon Choi, Jin Sung Kim, Hong-Gyun Wu, Jong Min Park, Jung-in Kim.  (2020)  Improvement in sensitivity of radiochromic 3D dosimeter based on rigid polyurethane resin by incorporating tartrazine.  PLoS One,  15  (3): (e0230410). 
8. Yaoping Hu, Zhijin Gao.  (2020)  Yellow emissive Se,N-codoped carbon dots toward sensitive fluorescence assay of crystal violet.  JOURNAL OF HAZARDOUS MATERIALS,  388  (122073). 
9. Ji Yang, Zheng-Zhong Lin, Zhi-Yong Huang.  (2020)  Rapid detection of trace malachite green using a fluorescence probe based on signal amplification through electrostatic self-assembly of CdTe QDs and polystyrene microsphere.  MARINE POLLUTION BULLETIN,  151  (110812). 
10. Fuyou Du, Lingshun Sun, Zhujun Huang, Zhengyi Chen, Zhigang Xu, Guihua Ruan, Chenxi Zhao.  (2020)  Electrospun reduced graphene oxide/TiO2/poly(acrylonitrile-co-maleic acid) composite nanofibers for efficient adsorption and photocatalytic removal of malachite green and leucomalachite green.  CHEMOSPHERE,  239  (124764). 
11. Qianqian Wang, Xiaofei Qin, Liping Geng, Yan Wang.  (2019)  Label-Free Electrochemical Aptasensor for Sensitive Detection of Malachite Green Based on Au Nanoparticle/Graphene Quantum Dots/Tungsten Disulfide Nanocomposites.  Nanomaterials,  (2): (229). 
12. Chunchen Zheng, Liying Zhang, Fangyuan Wang, Yueqing Cai, Shuhu Du, Zhongping Zhang.  (2018)  Silver nanoparticles/activated carbon composite as a facile SERS substrate for highly sensitive detection of endogenous formaldehyde in human urine by catalytic reaction.  TALANTA,  188  (630). 
13. Ji Yang, Hao Wu, Ming-Hui Wu, Jun Zeng, Zheng-Zhong Lin, Xiao-Mei Chen, Zhi-Yong Huang.  (2018)  Simultaneous detection of malachite & leucomalachite green based on dual template CdTe@MIP via normal and synchronous fluorescence quenching.  DYES AND PIGMENTS,  155  (171). 
14. Le Wu, Zheng-Zhong Lin, Jun Zeng, Hui-Ping Zhong, Xiao-Mei Chen, Zhi-Yong Huang.  (2018)  Detection of malachite green in fish based on magnetic fluorescent probe of CdTe QDs/nano-Fe3O4@MIPs.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  196  (117). 
15. Jia Jie, Yan Shang, Lai Xiaoxia, Xu Yongzhen, Liu Tong, Xiang Yuhong.  (2018)  Colorimetric Aptasensor for Detection of Malachite Green in Fish Sample Based on RNA and Gold Nanoparticles.  Food Analytical Methods,  11  (6): (1668-1676). 
16. He Xiao-Mei, Ding Jun, Yu Lei, Hussain Dilshad, Feng Yu-Qi.  (2016)  Black phosphorus-assisted laser desorption ionization mass spectrometry for the determination of low-molecular-weight compounds in biofluids.  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,  408  (22): (6223-6233). 
17. Baomei Huang, Xibin Zhou, Jing Chen, Guofan Wu, Xiaoquan Lu.  (2015)  Determination of malachite green in fish based on magnetic molecularly imprinted polymer extraction followed by electrochemiluminescence.  TALANTA,  142  (228). 
18. Hongzhi Wang, Yu Wang, Su Liu, Jinghua Yu, Wei Xu, Yuna Guo, Jiadong Huang.  (2014)  An RNA aptamer-based electrochemical biosensor for sensitive detection of malachite green.  RSC Advances,  (105): (60987-60994). 
19. Jin Dong Cho, Chang Heon Choi, Heerim Nam, Jung-in Kim.  (2024)  Improved sensitivity and ambient light stability of radiochromic plastic dosimeters through composite azo compounds.  RADIATION PHYSICS AND CHEMISTRY,  223  (111891). 
20. Guo Dongying, Yang Hailiang, Zhang Longyue, Dai Ruoyu, Huang Yuankui, Hu Yaoping.  (2025)  Smartphone-assisted detection of methylene blue using leaf-derived, dual-emissive carbon dots as ratiometric fluorescence probes.  MICROCHIMICA ACTA,  192  (3): (1-9). 

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