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Leucine Aminopeptidase, microsomal from porcine kidney, CAS No.9054-63-1

COA

Grade & Purity:

Type VI-S, lyophilized powder,≥12 units/mg protein (biuret)

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Item Number

L755285

Grouped product items
SKU	Size	Availability	Price
L755285-25U	25U	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$471.90
L755285-50U	50U	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$774.90
L755285-100U	100U	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,413.90

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Click to view protein information: ANPEP

Metabolite (5307)

Basic Description

Product Name	Leucine Aminopeptidase, microsomal from porcine kidney, CAS No.9054-63-1
Product Description	Leucine Aminopeptidase (LAP) from porcine is a 320-kDa exopeptidase present in cytosol. It contains zinc in its structure and belongs to the M1 and M17 peptidase families. LAP display bi-lobed structure and has the catalytic domain at the C-terminus and a variable N-terminal domain. Application: Leucine Aminopeptidase, microsomal from porcine kidney has been used in aminopeptidase N (APN) inhibitor screening assay in adenocarcinoma cell line ES-2 and in the inhibition kinetic studies with APN inhibitor.
Specifications & Purity	Type VI-S, lyophilized powder,≥12 units/mg protein (biuret)
Biochemical and Physiological Mechanisms	Leucine Aminopeptidase (LAP) catalyzes protein hydrolysis at the leucine residue at N-terminal. An altered level of LAP is implicated in tumor proliferation and progression. LAP is a potential biomarker for ovarian epithelial cancer therapy. Porcine LAP h

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
  - Class Indoles and derivatives
    - Subclass Carbazoles

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
Class	Indoles and derivatives
Subclass	Carbazoles
Intermediate Tree Nodes	Not available
Direct Parent	Carbazoles
Alternative Parents	Substituted pyrroles Benzene and substituted derivatives Pyrrolidines Heteroaromatic compounds Trialkylsilanes Propargyl-type 1,3-dipolar organic compounds Organic metalloid salts Formamidines Carboximidamides Azacyclic compounds Organopnictogen compounds Imines Hydrocarbon derivatives
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	Carbazole - Benzenoid - Substituted pyrrole - Monocyclic benzene moiety - Heteroaromatic compound - Pyrrolidine - Trialkylsilane - Formamidine - Azacycle - Organic metalloid salt - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Carboximidamide - Amidine - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Organic salt - Organosilicon compound - Alkylsilane - Organonitrogen compound - Imine - Aromatic heteropolycyclic compound
Description	This compound belongs to the class of organic compounds known as carbazoles. These are compounds containing a three ring system containing a pyrrole ring fused on either side to a benzene ring.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Storage and Shipping

Concentration	Type VI-S, lyophilized powder,≥12 units/mg protein (biuret)
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
CAS	9054-63-1
Enzyme Commission Number	3.4.11.2(BRENDA,IUBMB)

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