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L-Methionine sulfoximine - 98%, high purity , CAS No.15985-39-4

2 Citations COA COA
In stock
Item Number
M111096
Grouped product items
SKU Size
Availability
 Price Qty
M111096-50mg
50mg
3
$24.90
M111096-250mg
250mg
3
$79.90
M111096-500mg
500mg
3
$129.90
M111096-1g
1g
3
$199.90
M111096-5g
5g
1
$699.90
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Bulk Order  SDS  DATASHEET  Specification Sheet
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Amino Acid/Protein Metabolism (1836) inhibitor (73)

Basic Description

Synonyms (2S)-2-Amino-4-(S-methylsufonimidoyl)butanoic acid | (2S)-2-Amino-4-(S-methylsufonimidoyl)-butanoic acid | (E)-3-pyridin-3-ylprop-2-enoic acid | NCGC00094132-04 | MFCD00002621 | AKOS015892783 | L-Methionine sulfoximine | M 5379 | Prestwick0_000523 | SPBio
Specifications & Purity Moligand™, ≥98%
Biochemical and Physiological Mechanisms L-Methionine sulfoximine (MSX) enhances NH3 production in seedling leaves wheat, barley, corn and sorghum plants by inhibiting glutamine synthetase (GS) activity. Methionine sulfoximine (MSX) increases ornithine decarboxylase activity, decreases the survi
Storage Temp Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Grade Moligand™
Product Description

L-Methionine [R,S]-Sulfoximine inhibits both γGCS g-glutamylcysteine synthetase and Gl Syn (glutamine synthetase). Working concentrations for inhibition of g-glutamylcysteine synthetase are 0.2-2.0 mM (52% inhibition occured at 100 mM).

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Organic acids and derivatives
Class Carboxylic acids and derivatives
Subclass Amino acids, peptides, and analogues
Intermediate Tree Nodes Amino acids and derivatives - Alpha amino acids and derivatives - Alpha amino acids
Direct Parent L-alpha-amino acids
Alternative Parents Thia fatty acids  Carbo-azosulfones  Amino acids  Monocarboxylic acids and derivatives  Carboxylic acids  Organopnictogen compounds  Organic oxides  Monoalkylamines  Hydrocarbon derivatives  Carbonyl compounds  
Molecular Framework Aliphatic acyclic compounds
Substituents L-alpha-amino acid - Thia fatty acid - Fatty acid - Fatty acyl - Carbo-azosulfone - Amino acid - Carboxylic acid - Monocarboxylic acid or derivatives - Organopnictogen compound - Organic oxygen compound - Organic nitrogen compound - Primary amine - Organosulfur compound - Organooxygen compound - Organonitrogen compound - Amine - Primary aliphatic amine - Carbonyl group - Organic oxide - Hydrocarbon derivative - Aliphatic acyclic compound
Description This compound belongs to the class of organic compounds known as l-alpha-amino acids. These are alpha amino acids which have the L-configuration of the alpha-carbon atom.
External Descriptors non-proteinogenic L-alpha-amino acid - L-methionine derivative - methionine sulfoximine

Names and Identifiers

Pubchem Sid 488186540
Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/488186540
IUPAC Name (2S)-2-amino-4-(methylsulfonimidoyl)butanoic acid
INCHI InChI=1S/C5H12N2O3S/c1-11(7,10)3-2-4(6)5(8)9/h4,7H,2-3,6H2,1H3,(H,8,9)/t4-,11?/m0/s1
InChIKey SXTAYKAGBXMACB-DPVSGNNYSA-N
Smiles CS(=N)(=O)CCC(C(=O)O)N
Isomeric SMILES CS(=N)(=O)CC[C@@H](C(=O)O)N
WGK Germany 3
Molecular Weight 180.23
Beilstein 6175446
Reaxy-Rn 1725509
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1725509&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

33 results found

Lot Number Certificate Type Date Item
D2525480 Certificate of Analysis Apr 07, 2025 M111096
D2517518 Certificate of Analysis Apr 07, 2025 M111096
D2517519 Certificate of Analysis Apr 07, 2025 M111096
D2517531 Certificate of Analysis Apr 07, 2025 M111096
D2517532 Certificate of Analysis Apr 07, 2025 M111096
G2423142 Certificate of Analysis Jul 13, 2024 M111096
G2423427 Certificate of Analysis Jul 13, 2024 M111096
G2423428 Certificate of Analysis Jul 13, 2024 M111096
G2423429 Certificate of Analysis Jul 13, 2024 M111096
G2423431 Certificate of Analysis Jul 13, 2024 M111096
A2409398 Certificate of Analysis Dec 27, 2023 M111096
A2409399 Certificate of Analysis Dec 27, 2023 M111096
A2409400 Certificate of Analysis Dec 27, 2023 M111096
A2409401 Certificate of Analysis Dec 27, 2023 M111096
A2409402 Certificate of Analysis Dec 27, 2023 M111096
A2409403 Certificate of Analysis Dec 27, 2023 M111096
G2404059 Certificate of Analysis Dec 27, 2023 M111096
A2409391 Certificate of Analysis Dec 27, 2023 M111096
A2409392 Certificate of Analysis Dec 27, 2023 M111096
A2409393 Certificate of Analysis Dec 27, 2023 M111096
A2409404 Certificate of Analysis Dec 27, 2023 M111096
A2306612 Certificate of Analysis Nov 03, 2022 M111096
A2306716 Certificate of Analysis Nov 03, 2022 M111096
A2306710 Certificate of Analysis Nov 03, 2022 M111096
A2306581 Certificate of Analysis Nov 03, 2022 M111096
A2306718 Certificate of Analysis Nov 03, 2022 M111096
A2306759 Certificate of Analysis Nov 03, 2022 M111096
A2306711 Certificate of Analysis Nov 03, 2022 M111096
A2306627 Certificate of Analysis Nov 03, 2022 M111096
F2228436 Certificate of Analysis Jun 09, 2022 M111096
F2228453 Certificate of Analysis Jun 09, 2022 M111096
F2228454 Certificate of Analysis Jun 09, 2022 M111096
F2228462 Certificate of Analysis Jun 09, 2022 M111096

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Chemical and Physical Properties

Solubility DMSO: <1.8 mg/mL (10 mM)
Melt Point(°C) 210°C
Molecular Weight 180.230 g/mol
XLogP3 -1.800
Hydrogen Bond Donor Count 3
Hydrogen Bond Acceptor Count 5
Rotatable Bond Count 4
Exact Mass 180.057 Da
Monoisotopic Mass 180.057 Da
Topological Polar Surface Area 113.000 Ų
Heavy Atom Count 11
Formal Charge 0
Complexity 244.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 1
Undefined Atom Stereocenter Count 1
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 1

Alternative Products

  1. L-Methionine sulfoxide
    L-Methionine sulfoxide
    • ≥98%

    Starting at $35.90

  2. no_selection
    Acetyl-L-methionine sulfoxide

    Starting at $223.90

  3. Boc-Met(O)-OH
    Boc-Met(O)-OH
    • ≥98%

    Starting at $40.90

  4. DL-Methionine Sulfoxide
    DL-Methionine Sulfoxide
    • ≥98%(T)

    Starting at $12.90

Citations of This Product

How to Cite Aladdin Scientific Products?
1. Bin Du, Qingqing Jiao, Yimeng Bai, Min Yu, Mengxue Pang, Mengmeng Zhao, Huizhen Ma, Hanchun Yao.  (2022)  Glutamine Metabolism-Regulated Nanoparticles to Enhance Chemoimmunotherapy by Increasing Antigen Presentation Efficiency.  ACS Applied Materials & Interfaces,  14  (7): (8753–8765). 
2. Xinchong Shi, Xiangsong Zhang, Chang Yi, Yubo Liu, Qiao He.  (2015)  [13N]Ammonia Positron Emission Tomographic/Computed Tomographic Imaging Targeting Glutamine Synthetase Expression in Prostate Cancer.  Molecular Imaging,     

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