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L-Methionine - from non-animal source, meets EP, JP, USP, for cell culture, 99.0-101.0%, high purity , CAS No.63-68-3

In stock
Item Number
M101131
Grouped product items
SKU Size
Availability
Price Qty
M101131-25g
25g
4
$41.90
M101131-100g
100g
4
$82.90
M101131-500g
500g
1
$331.90

Essential amino acid.

Basic Description

Synonyms (35S)Methionine | carbon-11 methionine | L-2-Amino-4methylthiobutyric acid | METHIONINE [II] | L-Methionin | L-Methionine-34S | L-Methioninum | 1pg2 | Methionine [USAN:USP:INN:BAN] | MFCD00063097 | (2S)-2-amino-4-(methylsulfanyl)butanoic acid | METHIONINE
Specifications & Purity Moligand™, Animal Free, USP, JP, Ph.Eur., for cell culture, ≥99%
Storage Temp Protected from light
Shipped In Normal
Grade Animal Free, for cell culture, JP, Moligand™, Ph.Eur., USP
Note Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

L-Methionine is an essential amino acid for human development, hepatoprotectant, acetominophen poisoning antidote, and urinary acidifier.
An essential amino acid

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Organic acids and derivatives
Class Carboxylic acids and derivatives
Subclass Amino acids, peptides, and analogues
Intermediate Tree Nodes Amino acids and derivatives - Alpha amino acids and derivatives
Direct Parent Methionine and derivatives
Alternative Parents L-alpha-amino acids  Thia fatty acids  Amino acids  Sulfenyl compounds  Monocarboxylic acids and derivatives  Dialkylthioethers  Carboxylic acids  Organopnictogen compounds  Organic oxides  Monoalkylamines  Hydrocarbon derivatives  Carbonyl compounds  
Molecular Framework Aliphatic acyclic compounds
Substituents Methionine or derivatives - Alpha-amino acid - L-alpha-amino acid - Thia fatty acid - Fatty acid - Fatty acyl - Amino acid - Carboxylic acid - Monocarboxylic acid or derivatives - Thioether - Sulfenyl compound - Dialkylthioether - Amine - Organic oxygen compound - Primary amine - Organosulfur compound - Organooxygen compound - Organonitrogen compound - Organic nitrogen compound - Primary aliphatic amine - Carbonyl group - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Aliphatic acyclic compound
Description This compound belongs to the class of organic compounds known as methionine and derivatives. These are compounds containing methionine or a derivative thereof resulting from reaction of methionine at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom.
External Descriptors Common amino acids

Associated Targets(Human)

F2 Tclin Thrombin (11687 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ESR1 Tclin Estrogen receptor alpha (17718 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PGR Tclin Progesterone receptor (8562 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CHRM2 Tclin Muscarinic acetylcholine receptor M2 (10671 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HTR1A Tclin Serotonin 1a (5-HT1a) receptor (14969 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ADRA2A Tclin Alpha-2a adrenergic receptor (9450 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
AR Tclin Androgen Receptor (11781 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
GABRA1 Tclin GABA receptor alpha-1 subunit (399 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MAOA Tclin Monoamine oxidase A (11911 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
DRD1 Tclin Dopamine D1 receptor (9720 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ACHE Tclin Acetylcholinesterase (18204 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SLC6A2 Tclin Norepinephrine transporter (10102 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ADORA1 Tclin Adenosine A1 receptor (17603 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SLC6A4 Tclin Serotonin transporter (12625 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ADRA1A Tclin Alpha-1a adrenergic receptor (8359 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
OPRM1 Tclin Mu opioid receptor (19785 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
DRD3 Tclin Dopamine D3 receptor (14368 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SLC6A3 Tclin Dopamine transporter (10535 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PDE3A Tclin Phosphodiesterase 3A (3309 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HTR2B Tclin Serotonin 2b (5-HT2b) receptor (10323 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TBXA2R Tclin Thromboxane A2 receptor (5717 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PDE4A Tclin Phosphodiesterase 4A (1943 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HRH3 Tclin Histamine H3 receptor (10389 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
FASN Tchem Fatty acid synthase (3390 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Homo sapiens (32628 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SLC7A5 Tchem L-type amino acid transporter 1 (388 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Associated Targets(non-human)

Mat1a S-adenosylmethionine synthetase alpha and beta forms (31 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Mat2a S-adenosylmethionine synthetase gamma form (83 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Hdac6 Histone deacetylase 6 (222 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Pkm Pyruvate kinase isozymes M1/M2 (66 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Ggt1 Gamma-glutamyltranspeptidase 1 (36 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Pyricularia grisea (1253 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Oryza sativa (2923 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
luxS S-ribosylhomocysteine lyase (12 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Slc16a10 Monocarboxylate transporter 10 (73 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Mat1a S-adenosylmethionine synthetase (MAT 1 and MAT 2) (155 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Slc1a5 Amino acid transporter (271 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

Pubchem Sid 504751010
Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504751010
IUPAC Name (2S)-2-amino-4-methylsulfanylbutanoic acid
INCHI InChI=1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1
InChIKey FFEARJCKVFRZRR-BYPYZUCNSA-N
Smiles CSCC[C@H](N)C(O)=O
Isomeric SMILES CSCC[C@@H](C(=O)O)N
WGK Germany 1
RTECS PD0457000
Molecular Weight 149.21
Beilstein 1722294
Reaxy-Rn 1722294
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1722294&ln=

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

17 results found

Lot Number Certificate Type Date Item
F2526036 Certificate of Analysis Jul 08, 2025 M101131
B2310342 Certificate of Analysis Aug 03, 2022 M101131
B2310338 Certificate of Analysis Aug 03, 2022 M101131
H2211032 Certificate of Analysis Aug 03, 2022 M101131
I2202572 Certificate of Analysis Aug 03, 2022 M101131
F2526034 Certificate of Analysis Aug 03, 2022 M101131
I2202571 Certificate of Analysis Aug 03, 2022 M101131
I2202573 Certificate of Analysis Aug 03, 2022 M101131
K2413104 Certificate of Analysis Aug 03, 2022 M101131
I2202574 Certificate of Analysis Aug 03, 2022 M101131
J2228114 Certificate of Analysis Aug 03, 2022 M101131
L2318026 Certificate of Analysis Nov 27, 2021 M101131
C2415112 Certificate of Analysis Nov 27, 2021 M101131
J2317037 Certificate of Analysis Nov 27, 2021 M101131
G2225037 Certificate of Analysis Nov 27, 2021 M101131
I2420030 Certificate of Analysis Nov 27, 2021 M101131
D2320079 Certificate of Analysis Nov 27, 2021 M101131

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Chemical and Physical Properties

Solubility Soluble in 1M HCl (50 mg/ml), and water (56.6 mg/ml at 25 °C). Insoluble in ethanol, acetone, and ether.
Sensitivity Light sensitive.
Specific Rotation[α] 24° (C=8,HCl (1+1))
Melt Point(°C) 280-282°C
Molecular Weight 149.210 g/mol
XLogP3 -1.900
Hydrogen Bond Donor Count 2
Hydrogen Bond Acceptor Count 4
Rotatable Bond Count 4
Exact Mass 149.051 Da
Monoisotopic Mass 149.051 Da
Topological Polar Surface Area 88.600 Ų
Heavy Atom Count 9
Formal Charge 0
Complexity 97.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 1
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 1

Citations of This Product

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