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(L)-Dehydroascorbic acid - Moligand™, ≥95%, high purity , CAS No.490-83-5

COA

Grade & Purity:

Moligand™

≥95%

Cas Number: 490-83-5
Molecular Weight: 174.11
MDL number: MFCD00066467
PubChem CID: 440667

In stock

Item Number

L1374153

Grouped product items
SKU	Size	Availability	Price	Qty
L1374153-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$23.90
L1374153-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$33.90

GLUT1 substrate; oxidized form ofL-Ascorbic acid

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Metabolite (5307)

Basic Description

Specifications & Purity	Moligand™, ≥95%
Biochemical and Physiological Mechanisms	Oxidized form ofL-Ascorbic acid. Transported into cells through GLUT1. Selectively induces cell death inKRASandBRAFmutant cellsin vitro.
Storage Temp	Protected from light,Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Grade	Moligand™
Product Description	(L)-Dehydroascorbic acid (DHA) is a potent glycation agent that is produced by the oxidation of ascorbic acid (vitamin C). In vitro studies revealed that DHA is significantly more reactive than glucose and fructose in the glycation of lens proteins. Thus, DHA could be a critical precursor for the in vivo formation of advanced glycation end products (AGEs). DHA is a dimer when it is solid, but when it is dissolved in a solution, it becomes a monomer.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
  - Class Lactones
    - Subclass Gamma butyrolactones

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
Class	Lactones
Subclass	Gamma butyrolactones
Intermediate Tree Nodes	Not available
Direct Parent	Gamma butyrolactones
Alternative Parents	Furanones Tetrahydrofurans Secondary alcohols Cyclic ketones Carboxylic acid esters 1,2-diols Oxacyclic compounds Monocarboxylic acids and derivatives Primary alcohols Organic oxides Hydrocarbon derivatives
Molecular Framework	Aliphatic heteromonocyclic compounds
Substituents	3-furanone - Gamma butyrolactone - Tetrahydrofuran - 1,2-diol - Carboxylic acid ester - Cyclic ketone - Secondary alcohol - Ketone - Carboxylic acid derivative - Oxacycle - Monocarboxylic acid or derivatives - Alcohol - Hydrocarbon derivative - Organic oxide - Organic oxygen compound - Carbonyl group - Primary alcohol - Organooxygen compound - Aliphatic heteromonocyclic compound
Description	This compound belongs to the class of organic compounds known as gamma butyrolactones. These are compounds containing a gamma butyrolactone moiety, which consists of an aliphatic five-member ring with four carbon atoms, one oxygen atom, and bears a ketone group on the carbon adjacent to the oxygen atom.
External Descriptors	dehydroascorbic acid
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Names and Identifiers

IUPAC Name	(5R)-5-[(1S)-1,2-dihydroxyethyl]oxolane-2,3,4-trione
INCHI	InChI=1S/C6H6O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-8H,1H2/t2-,5+/m0/s1
InChIKey	SBJKKFFYIZUCET-JLAZNSOCSA-N
Smiles	C(C(C1C(=O)C(=O)C(=O)O1)O)O
Isomeric SMILES	C([C@@H]([C@@H]1C(=O)C(=O)C(=O)O1)O)O
WGK Germany	3
Molecular Weight	174.11
Reaxy-Rn	1345285
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1345285&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Chemical and Physical Properties

Solubility	Solvent:water, Max Conc. mg/mL: 1.74, Max Conc. mM: 10 with gentle warming; Solvent:DMSO, Max Conc. mg/mL: 17.41, Max Conc. mM: 100
Sensitivity	Light sensitive
Melt Point(°C)	228 °C (dec.) (lit.)
Molecular Weight	174.110 g/mol
XLogP3	-1.000
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	2
Exact Mass	174.016 Da
Monoisotopic Mass	174.016 Da
Topological Polar Surface Area	101.000 Å²
Heavy Atom Count	12
Formal Charge	0
Complexity	244.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	2
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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