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L-741,742 hydrochloride - ≥98%(HPLC), high purity , CAS No.874882-93-6

COA

Grade & Purity:

≥98%(HPLC)

Cas Number: 874882-93-6
Molecular Weight: 417.38
PubChem CID: 24744861

In stock

Item Number

L288128

Grouped product items
SKU	Size	Availability	Price
L288128-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$98.90
L288128-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$151.90
L288128-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$339.90
L288128-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$625.90
L288128-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,125.90

Highly selective D4antagonist

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Class A GPCR (4138) D4 Receptors / D4 Receptor Antagonists (1) Dopamine Receptors (3)

Basic Description

Synonyms	C22H31N3O3.2HCl \| SR-01000597843 \| SR-01000597843-1 \| 79Y3N86U2E \| UNII-79Y3N86U2E \| AKOS024456331 \| L 741742 \| 8-[2-[4-(methoxyphenyl)-1-piperazin yl]ethyl]-8-azaspiro[4.5]decane-7,9-dione dihydrochloride \| L-741,742Hydrochloride \| 4-[5-(4-chlorophenyl)-
Specifications & Purity	≥98%(HPLC)
Biochemical and Physiological Mechanisms	A potent and highly selective D4dopamine receptor antagonist, with Kivalues of > 1700, 770 and 3.5 nM at cloned human D2, D3and D4receptors.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	Product Describtion: highly potent and selective D4 dopamine receptor antagonist.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Benzenoids
  - Class Benzene and substituted derivatives
    - Subclass Phenethylamines

Kingdom	Organic compounds
Superclass	Benzenoids
Class	Benzene and substituted derivatives
Subclass	Phenethylamines
Intermediate Tree Nodes	Not available
Direct Parent	Phenethylamines
Alternative Parents	Chlorobenzenes Aralkylamines Piperidines Aryl chlorides Isoxazoles Heteroaromatic compounds Trialkylamines Oxacyclic compounds Azacyclic compounds Organooxygen compounds Organochlorides Hydrochlorides Hydrocarbon derivatives
Molecular Framework	Aromatic heteromonocyclic compounds
Substituents	Phenethylamine - Chlorobenzene - Halobenzene - Aralkylamine - Aryl chloride - Piperidine - Aryl halide - Heteroaromatic compound - Azole - Isoxazole - Tertiary aliphatic amine - Tertiary amine - Oxacycle - Azacycle - Organoheterocyclic compound - Organic oxygen compound - Organochloride - Organohalogen compound - Organonitrogen compound - Amine - Organooxygen compound - Organic nitrogen compound - Hydrochloride - Hydrocarbon derivative - Aromatic heteromonocyclic compound
Description	This compound belongs to the class of organic compounds known as phenethylamines. These are compounds containing a phenethylamine moiety, which consists of a phenyl group substituted at the second position by an ethan-1-amine.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Names and Identifiers

IUPAC Name	5-(4-chlorophenyl)-4-methyl-3-[1-(2-phenylethyl)piperidin-4-yl]-1,2-oxazole;hydrochloride
INCHI	InChI=1S/C23H25ClN2O.ClH/c1-17-22(25-27-23(17)20-7-9-21(24)10-8-20)19-12-15-26(16-13-19)14-11-18-5-3-2-4-6-18;/h2-10,19H,11-16H2,1H3;1H
InChIKey	HZRPUQURUAXOHB-UHFFFAOYSA-N
Smiles	CC1=C(ON=C1C2CCN(CC2)CCC3=CC=CC=C3)C4=CC=C(C=C4)Cl.Cl
Isomeric SMILES	CC1=C(ON=C1C2CCN(CC2)CCC3=CC=CC=C3)C4=CC=C(C=C4)Cl.Cl
PubChem CID	24744861
Molecular Weight	417.38

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Chemical and Physical Properties

Solubility	Solvent:DMSO, Max Conc. mg/mL: 4.17, Max Conc. mM: 10
Molecular Weight	417.400 g/mol
XLogP3
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	5
Exact Mass	416.142 Da
Monoisotopic Mass	416.142 Da
Topological Polar Surface Area	29.300 Å²
Heavy Atom Count	28
Formal Charge	0
Complexity	440.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	2

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