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L 012 sodium salt - ≥98%(HPLC), high purity , CAS No.143556-24-5

COA

Grade & Purity:

≥98%(HPLC)

Cas Number: 143556-24-5
Molecular Weight: 310.67
PubChem CID: 154730618
PubChem SID: 504773670

In stock

Item Number

L287250

Grouped product items
SKU	Size	Availability	Price
L287250-1mg	1mg	3	$35.90
L287250-5mg	5mg	2	$120.90
L287250-10mg	10mg	1	$186.90
L287250-25mg	25mg	1	$321.90
L287250-50mg	50mg	1	$513.90

Chemiluminescent ROS and RNS indicator

View related series

Glucose Metabolism (1943) Immunology/Inflammation (1929) Metabolic Enzyme/Protease (4860) NF-κB (747) Reactive Oxygen Species (309)

Basic Description

Synonyms	sodium 8-amino-5-chloro-4-oxo-7-phenyl-3,4-dihydropyrido[3,4-d]pyridazin-1-olate \| L012 sodium \| sodium;8-amino-5-chloro-4-oxo-7-phenyl-3H-pyrido[3,4-d]pyridazin-1-olate \| L 012 sodium salt
Specifications & Purity	≥98%(HPLC)
Biochemical and Physiological Mechanisms	Luminal-based chemiluminescent probe. Detects NAPDH oxidase-derived reactive oxygen and nitrogen species (ROS and RNS). Activein vitroandin vivo.
Storage Temp	Protected from light,Store at -20°C,Argon charged
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	Product Describtion: L 012 sodium salt a luminol-based chemiluminescent (CL) probe, is widely used in vitro and in vivo to detect NADPH oxidase (Nox)-derived superoxide (O2•−) and identify Nox inhibitors.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
  - Class Pyridines and derivatives
    - Subclass Phenylpyridines

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
Class	Pyridines and derivatives
Subclass	Phenylpyridines
Intermediate Tree Nodes	Not available
Direct Parent	Phenylpyridines
Alternative Parents	Pyridazinones 2-halopyridines Aminopyridines and derivatives Aryl chlorides Benzene and substituted derivatives Vinylogous amides Heteroaromatic compounds Lactams Azacyclic compounds Organic metal halides Hydrocarbon derivatives Organic sodium salts Organic zwitterions Primary amines Organochlorides Organic oxides Organooxygen compounds
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	2-phenylpyridine - Aminopyridine - 2-halopyridine - Pyridazinone - Aryl chloride - Aryl halide - Monocyclic benzene moiety - Pyridazine - Benzenoid - Heteroaromatic compound - Vinylogous amide - Lactam - Organic metal halide - Azacycle - Organic alkali metal salt - Primary amine - Organic nitrogen compound - Organooxygen compound - Organonitrogen compound - Organochloride - Organohalogen compound - Hydrocarbon derivative - Organic oxide - Amine - Organic oxygen compound - Organic sodium salt - Organic zwitterion - Organic salt - Aromatic heteropolycyclic compound
Description	This compound belongs to the class of organic compounds known as phenylpyridines. These are polycyclic aromatic compounds containing a benzene ring linked to a pyridine ring through a CC or CN bond.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Names and Identifiers

Pubchem Sid	504773670
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/504773670
IUPAC Name	sodium;8-amino-5-chloro-4-oxo-7-phenyl-3H-pyrido[3,4-d]pyridazin-1-olate
INCHI	InChI=1S/C13H9ClN4O2.Na/c14-11-8-7(12(19)17-18-13(8)20)9(15)10(16-11)6-4-2-1-3-5-6;/h1-5H,15H2,(H,17,19)(H,18,20);/q;+1/p-1
InChIKey	IGEUYSJHQQCEFP-UHFFFAOYSA-M
Smiles	C1=CC=C(C=C1)C2=C(C3=C(C(=O)NN=C3[O-])C(=N2)Cl)N.[Na+]
Isomeric SMILES	C1=CC=C(C=C1)C2=C(C3=C(C(=O)NN=C3[O-])C(=N2)Cl)N.[Na+]
Molecular Weight	310.67
Reaxy-Rn	30826882
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=30826882&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

17 results found

Lot Number	Certificate Type	Date	Item
J2415696	Certificate of Analysis	Oct 10, 2024	L287250
J2415669	Certificate of Analysis	Oct 10, 2024	L287250
J2415686	Certificate of Analysis	Oct 10, 2024	L287250
C2521272	Certificate of Analysis	Oct 10, 2024	L287250
J2415695	Certificate of Analysis	Oct 10, 2024	L287250
I2328087	Certificate of Analysis	Sep 14, 2023	L287250
I2328082	Certificate of Analysis	Sep 14, 2023	L287250
I2328083	Certificate of Analysis	Sep 14, 2023	L287250
E2416018	Certificate of Analysis	Sep 14, 2023	L287250
I2328089	Certificate of Analysis	Sep 14, 2023	L287250
E2415053	Certificate of Analysis	Sep 14, 2023	L287250
I2328085	Certificate of Analysis	Sep 14, 2023	L287250
I2328086	Certificate of Analysis	Sep 14, 2023	L287250
I2328088	Certificate of Analysis	Sep 14, 2023	L287250
I2328090	Certificate of Analysis	Sep 14, 2023	L287250
I2328091	Certificate of Analysis	Sep 14, 2023	L287250
I2328084	Certificate of Analysis	Sep 14, 2023	L287250

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Chemical and Physical Properties

Solubility	Solvent:water, Max Conc. mg/mL: 6.21, Max Conc. mM: 20; Solvent:DMSO, Max Conc. mg/mL: 31.07, Max Conc. mM: 100
Sensitivity	Moisture sensitive；Light sensitive

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