Skip to the beginning of the images gallery

KYA 1797K - 96%, high purity , CAS No.1956356-56-1

COA

Grade & Purity:

≥96%

Cas Number: 1956356-56-1
Molecular Weight: 442.5
PubChem CID: 119057297
PubChem SID: 488202665

In stock

Item Number

K286855

Grouped product items
SKU	Size	Availability	Price
K286855-5mg	5mg	3	$82.90
K286855-10mg	10mg	2	$141.90
K286855-25mg	25mg	1	$307.90
K286855-50mg	50mg	1	$521.90
K286855-100mg	100mg	1	$937.90

Wnt/β-catenin signaling inhibitor

View related series

Stem Cell/Wnt (1019) Wnt (104) β-catenin (56)

Basic Description

Synonyms	(5Z)-5-[[5-(4-Nitrophenyl)-2-furanyl]methylene]-4-oxo-2-thioxo-3-thiazolidinepropanoic acid potassium salt \| (Z)-3-(5-((5-(4-nitrophenyl)furan-2-yl)methylene)-4-oxo-2-thioxothiazolidin-3-yl)propanoic acid potassium salt, KYA1797 potassium salt
Specifications & Purity	≥96%
Biochemical and Physiological Mechanisms	Wnt/β-catenin signaling inhibitor (IC50= 0.75 μM). Increases binding affinity of β-catenin for axin, GSK-3β and β-TrCP. Promotes formation of the destruction complex, activation of GSK-3β and phosphorylation of β-catenin and K-Ras, leading to their degrad
Storage Temp	Store at -20°C,Argon charged
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.

Names and Identifiers

Pubchem Sid	488202665
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488202665
IUPAC Name	potassium;3-[(5Z)-5-[[5-(4-nitrophenyl)furan-2-yl]methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]propanoate
INCHI	InChI=1S/C17H12N2O6S2.K/c20-15(21)7-8-18-16(22)14(27-17(18)26)9-12-5-6-13(25-12)10-1-3-11(4-2-10)19(23)24;/h1-6,9H,7-8H2,(H,20,21);/q;+1/p-1/b14-9-;
InChIKey	PHUNRLYHXGMOLG-WQRRWHLMSA-M
Smiles	C1=CC(=CC=C1C2=CC=C(O2)C=C3C(=O)N(C(=S)S3)CCC(=O)[O-])[N+](=O)[O-].[K+]
Molecular Weight	442.5
Reaxy-Rn	30137268
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=30137268&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

11 results found

Lot Number	Certificate Type	Date	Item
C23181338	Certificate of Analysis	Dec 21, 2022	K286855
C23181314	Certificate of Analysis	Dec 21, 2022	K286855
C23181315	Certificate of Analysis	Dec 21, 2022	K286855
C23181316	Certificate of Analysis	Dec 21, 2022	K286855
C23181330	Certificate of Analysis	Dec 21, 2022	K286855
C23181339	Certificate of Analysis	Dec 21, 2022	K286855
C23181340	Certificate of Analysis	Dec 21, 2022	K286855
C23181362	Certificate of Analysis	Dec 21, 2022	K286855
C23181317	Certificate of Analysis	Dec 21, 2022	K286855
C23181344	Certificate of Analysis	Dec 21, 2022	K286855
C2527068	Certificate of Analysis	Dec 21, 2022	K286855

Show more⌵

Chemical and Physical Properties

Solubility	Solvent:DMSO, Max Conc. mg/mL: 2.21, Max Conc. mM: 5 with gentle warming
Sensitivity	Moisture sensitive
Molecular Weight	442.500 g/mol
XLogP3
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	4
Exact Mass	441.97 Da
Monoisotopic Mass	441.97 Da
Topological Polar Surface Area	177.000 Å²
Heavy Atom Count	28
Formal Charge	0
Complexity	663.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	1
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	1
Covalently-Bonded Unit Count	2

Solution Calculators

Molarity Calculator

Determine the necessary mass, volume, or concentration for preparing a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions, always use the batch-specific molecular weight of the product found on the vial label and the Certificate of Analysis (available online).

Dilution Calculator

Determine the dilution needed to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator enables you to quickly determine the volume of a reagent needed to reconstitute your vial. Just enter the mass of the reagent and the target concentration, and the calculator will do the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration