Skip to the beginning of the images gallery

KN-93 Phosphate - ≥99%, high purity , CAS No.1188890-41-6

COA

Grade & Purity:

≥99%

Cas Number: 1188890-41-6
Molecular Weight: 599.03
PubChem CID: 16760530
PubChem SID: 504768534

In stock

Item Number

K274961

Grouped product items
SKU	Size	Availability	Price
K274961-1mg	1mg	2	$133.90
K274961-5mg	5mg	2	$602.90
K274961-10mg	10mg	2	$1,084.90
K274961-25mg	25mg	2	$2,441.90
K274961-50mg	50mg	2	$4,394.90
K274961-100mg	100mg	2	$7,909.90

Potent, specific CaMK II inhibitor

Basic Description

Synonyms	1188890-41-6 \| s7423 \| KN 93 phosphate \| KN-93 phosphate (water soluble) \| F20700 \| HB0360 \| EX-A2086 \| N-[2-[[[3-(4-Chlorophenyl)-2-propenyl]methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4-methoxybenzenesulphonamide phosphate \| AC-33085 \| (E)-N-(2-(((3-(
Specifications & Purity	≥99%
Biochemical and Physiological Mechanisms	Potent, specific and cell-permeable calmodulin-dependent protein kinase (CaMK) II inhibitor (IC 50 = 370 nM). Also a potent and direct extracellular open channel voltage-gated potassium channel blocker (IC 50 = 307 nM for Kv1.5).
Storage Temp	Protected from light,Store at -20°C,Desiccated
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Note	Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description	Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions.

Names and Identifiers

Pubchem Sid	504768534
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/504768534
IUPAC Name	N-[2-[[[(E)-3-(4-chlorophenyl)prop-2-enyl]-methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4-methoxybenzenesulfonamide;phosphoric acid
INCHI	InChI=1S/C26H29ClN2O4S.H3O4P/c1-28(17-5-6-21-9-11-23(27)12-10-21)20-22-7-3-4-8-26(22)29(18-19-30)34(31,32)25-15-13-24(33-2)14-16-25;1-5(2,3)4/h3-16,30H,17-20H2,1-2H3;(H3,1,2,3,4)/b6-5+;
InChIKey	NNKJTPOXLIILMB-IPZCTEOASA-N
Smiles	CN(CC=CC1=CC=C(C=C1)Cl)CC2=CC=CC=C2N(CCO)S(=O)(=O)C3=CC=C(C=C3)OC.OP(=O)(O)O
Isomeric SMILES	CN(C/C=C/C1=CC=C(C=C1)Cl)CC2=CC=CC=C2N(CCO)S(=O)(=O)C3=CC=C(C=C3)OC.OP(=O)(O)O
Molecular Weight	599.03
Reaxy-Rn	18467446
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=18467446&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

7 results found

Lot Number	Certificate Type	Date	Item
D2418078	Certificate of Analysis	Mar 18, 2024	K274961
H2223520	Certificate of Analysis	Jun 07, 2023	K274961
H2223456	Certificate of Analysis	Jun 07, 2023	K274961
H2223342	Certificate of Analysis	Jun 06, 2023	K274961
H2223279	Certificate of Analysis	Jun 06, 2023	K274961
H2223278	Certificate of Analysis	Jun 06, 2023	K274961
H2223277	Certificate of Analysis	Jun 06, 2023	K274961

Chemical and Physical Properties

Solubility	Soluble in water to 100 mM and in DMSO to 100 mM
Sensitivity	light sensitive
Molecular Weight	599.000 g/mol
XLogP3
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	10
Rotatable Bond Count	11
Exact Mass	598.131 Da
Monoisotopic Mass	598.131 Da
Topological Polar Surface Area	156.000 Å²
Heavy Atom Count	39
Formal Charge	0
Complexity	763.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	1
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	1
Covalently-Bonded Unit Count	2

Solution Calculators

Molarity Calculator

Determine the necessary mass, volume, or concentration for preparing a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions, always use the batch-specific molecular weight of the product found on the vial label and the Certificate of Analysis (available online).

Dilution Calculator

Determine the dilution needed to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator enables you to quickly determine the volume of a reagent needed to reconstitute your vial. Just enter the mass of the reagent and the target concentration, and the calculator will do the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration