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Kevetrin hydrochloride - 10mM in DMSO, high purity , CAS No.66592-89-0

    Grade & Purity:
  • 10mM in DMSO
In stock
Item Number
K425351
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SKU Size
Availability
Price Qty
K425351-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$69.90

p53 Activators

Basic Description

Synonyms Kevetrin hydrochloride | 66592-89-0 | KEVETRIN | Kevetrin Hcl | Kevetrin (hydrochloride) | 4-Isothioureidobutyronitrile hydrochloride | UNII-NL6L2371DP | NSC 525990 | 500863-50-3 | 66592-89-0 (HCl) | NL6L2371DP | 3-Cyanopropyl carbamimidothioate hydrochloride | Carbamimidothioic
Specifications & Purity 10mM in DMSO
Biochemical and Physiological Mechanisms Kevetrin hydrochloride (Thioureidobutyronitrile) is a water-soluble, small molecule and activator of the tumor suppressor protein p53, with potential antineoplastic activity.
Storage Temp Store at -80°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Product Description

Information

Kevetrin hydrochloride Kevetrin hydrochloride (Thioureidobutyronitrile) is a water-soluble, small molecule and activator of the tumor suppressor protein p53 , with potential antineoplastic activity.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Organosulfur compounds
Class Isothioureas
Subclass Not available
Intermediate Tree Nodes Not available
Direct Parent Isothioureas
Alternative Parents Sulfenyl compounds  Nitriles  Carboximidamides  Imines  Hydrochlorides  Hydrocarbon derivatives  
Molecular Framework Aliphatic acyclic compounds
Substituents Isothiourea - Sulfenyl compound - Carboximidamide - Nitrile - Carbonitrile - Organic nitrogen compound - Cyanide - Hydrocarbon derivative - Hydrochloride - Organonitrogen compound - Imine - Aliphatic acyclic compound
Description This compound belongs to the class of organic compounds known as isothioureas. These are organic compounds containing the isothiourea group, with the general structure R1SC(=NR2)N(R3)R4 (R1,R2,R3,R4=H, alkyl, aryl).
External Descriptors Not available

Product Properties

ALogP 1.105
HBD Count 1
Rotatable Bond 4

Names and Identifiers

IUPAC Name 3-cyanopropyl carbamimidothioate;hydrochloride
INCHI InChI=1S/C5H9N3S.ClH/c6-3-1-2-4-9-5(7)8;/h1-2,4H2,(H3,7,8);1H
InChIKey NCXJZJFDQMKRKM-UHFFFAOYSA-N
Smiles C(CC#N)CSC(=N)N.Cl
Isomeric SMILES C(CC#N)CSC(=N)N.Cl
Molecular Weight 179.67
Reaxy-Rn 3689214
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3689214&ln=

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Chemical and Physical Properties

DMSO(mg / mL) Max Solubility 36
DMSO(mM) Max Solubility 200.36734012356
Water(mg / mL) Max Solubility 36
Water(mM) Max Solubility 200.36734012356
Molecular Weight 179.670 g/mol
XLogP3
Hydrogen Bond Donor Count 3
Hydrogen Bond Acceptor Count 3
Rotatable Bond Count 4
Exact Mass 179.028 Da
Monoisotopic Mass 179.028 Da
Topological Polar Surface Area 99.000 Ų
Heavy Atom Count 10
Formal Charge 0
Complexity 134.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 2

Solution Calculators

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