Determine the necessary mass, volume, or concentration for preparing a solution.
This is a demo store. No orders will be fulfilled.
| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
|
K425351-1ml
|
1ml |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$69.90
|
|
p53 Activators
| Synonyms | Kevetrin hydrochloride | 66592-89-0 | KEVETRIN | Kevetrin Hcl | Kevetrin (hydrochloride) | 4-Isothioureidobutyronitrile hydrochloride | UNII-NL6L2371DP | NSC 525990 | 500863-50-3 | 66592-89-0 (HCl) | NL6L2371DP | 3-Cyanopropyl carbamimidothioate hydrochloride | Carbamimidothioic |
|---|---|
| Specifications & Purity | 10mM in DMSO |
| Biochemical and Physiological Mechanisms | Kevetrin hydrochloride (Thioureidobutyronitrile) is a water-soluble, small molecule and activator of the tumor suppressor protein p53, with potential antineoplastic activity. |
| Storage Temp | Store at -80°C |
| Shipped In |
Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available. |
| Product Description |
Information Kevetrin hydrochloride Kevetrin hydrochloride (Thioureidobutyronitrile) is a water-soluble, small molecule and activator of the tumor suppressor protein p53 , with potential antineoplastic activity. |
Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organosulfur compounds |
| Class | Isothioureas |
| Subclass | Not available |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Isothioureas |
| Alternative Parents | Sulfenyl compounds Nitriles Carboximidamides Imines Hydrochlorides Hydrocarbon derivatives |
| Molecular Framework | Aliphatic acyclic compounds |
| Substituents | Isothiourea - Sulfenyl compound - Carboximidamide - Nitrile - Carbonitrile - Organic nitrogen compound - Cyanide - Hydrocarbon derivative - Hydrochloride - Organonitrogen compound - Imine - Aliphatic acyclic compound |
| Description | This compound belongs to the class of organic compounds known as isothioureas. These are organic compounds containing the isothiourea group, with the general structure R1SC(=NR2)N(R3)R4 (R1,R2,R3,R4=H, alkyl, aryl). |
| External Descriptors | Not available |
|
|
|
| ALogP | 1.105 |
|---|---|
| HBD Count | 1 |
| Rotatable Bond | 4 |
| IUPAC Name | 3-cyanopropyl carbamimidothioate;hydrochloride |
|---|---|
| INCHI | InChI=1S/C5H9N3S.ClH/c6-3-1-2-4-9-5(7)8;/h1-2,4H2,(H3,7,8);1H |
| InChIKey | NCXJZJFDQMKRKM-UHFFFAOYSA-N |
| Smiles | C(CC#N)CSC(=N)N.Cl |
| Isomeric SMILES | C(CC#N)CSC(=N)N.Cl |
| Molecular Weight | 179.67 |
| Reaxy-Rn | 3689214 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3689214&ln= |
| DMSO(mg / mL) Max Solubility | 36 |
|---|---|
| DMSO(mM) Max Solubility | 200.36734012356 |
| Water(mg / mL) Max Solubility | 36 |
| Water(mM) Max Solubility | 200.36734012356 |
| Molecular Weight | 179.670 g/mol |
| XLogP3 | |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 4 |
| Exact Mass | 179.028 Da |
| Monoisotopic Mass | 179.028 Da |
| Topological Polar Surface Area | 99.000 Ų |
| Heavy Atom Count | 10 |
| Formal Charge | 0 |
| Complexity | 134.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 2 |