JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.

This is a demo store. No orders will be fulfilled.

Account

Settings

Language

྾

Home
Small Molecules & Compound Libraries
Signaling Pathways
Apoptosis
Apoptosis
Kevetrin hydrochloride - 99%, high purity , CAS No.66592-89-0

Skip to the end of the images gallery

Skip to the beginning of the images gallery

Kevetrin hydrochloride - 99%, high purity , CAS No.66592-89-0

COA

Grade & Purity:

≥99%

Cas Number: 66592-89-0
Molecular Weight: 179.67
PubChem CID: 49778916
PubChem SID: 504770920

In stock

Item Number

K413339

Grouped product items
SKU	Size	Availability	Price
K413339-5mg	5mg	3	$45.90
K413339-10mg	10mg	3	$75.90
K413339-25mg	25mg	3	$171.90
K413339-50mg	50mg	3	$238.90
K413339-100mg	100mg	2	$401.90
K413339-500mg	500mg	2	$1,207.90

p53 Activators

View related series

Apoptosis (4276) Intrinsic Pathway (690) MDM-2/p53 (109)

Basic Description

Synonyms	Carbamimidothioic acid, 3-cyanopropyl ester, monohydrochloride \| EX-A627 \| AS-71143 \| s5811 \| 66592-89-0 (HCl) \| HY-16271 \| KEVETRIN \| Kevetrin, nsc 525990 \| N11407 \| 4-Isothioureidobutyronitrile hydrochloride;thioureidobutyronitrile hydrochloride;thioure
Specifications & Purity	≥99%
Biochemical and Physiological Mechanisms	Kevetrin hydrochloride (Thioureidobutyronitrile) is a water-soluble, small molecule and activator of the tumor suppressor protein p53, with potential antineoplastic activity.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	Information Kevetrin hydrochloride Kevetrin hydrochloride (Thioureidobutyronitrile) is a water-soluble, small molecule and activator of the tumor suppressor protein p53 , with potential antineoplastic activity.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organosulfur compounds
  - Class Isothioureas

Kingdom	Organic compounds
Superclass	Organosulfur compounds
Class	Isothioureas
Subclass	Not available
Intermediate Tree Nodes	Not available
Direct Parent	Isothioureas
Alternative Parents	Sulfenyl compounds Nitriles Carboximidamides Imines Hydrochlorides Hydrocarbon derivatives
Molecular Framework	Aliphatic acyclic compounds
Substituents	Isothiourea - Sulfenyl compound - Carboximidamide - Nitrile - Carbonitrile - Organic nitrogen compound - Cyanide - Hydrocarbon derivative - Hydrochloride - Organonitrogen compound - Imine - Aliphatic acyclic compound
Description	This compound belongs to the class of organic compounds known as isothioureas. These are organic compounds containing the isothiourea group, with the general structure R1SC(=NR2)N(R3)R4 (R1,R2,R3,R4=H, alkyl, aryl).
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Product Properties

ALogP	1.105
HBD Count	1
Rotatable Bond	4

Names and Identifiers

Pubchem Sid	504770920
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/504770920
IUPAC Name	3-cyanopropyl carbamimidothioate;hydrochloride
INCHI	InChI=1S/C5H9N3S.ClH/c6-3-1-2-4-9-5(7)8;/h1-2,4H2,(H3,7,8);1H
InChIKey	NCXJZJFDQMKRKM-UHFFFAOYSA-N
Smiles	C(CC#N)CSC(=N)N.Cl
Isomeric SMILES	C(CC#N)CSC(=N)N.Cl
Molecular Weight	179.67
Reaxy-Rn	3689214
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3689214&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

6 results found

Lot Number	Certificate Type	Date	Item
F2229401	Certificate of Analysis	Apr 03, 2025	K413339
F2229403	Certificate of Analysis	Apr 03, 2025	K413339
F2229400	Certificate of Analysis	Apr 03, 2025	K413339
F2229399	Certificate of Analysis	Apr 03, 2025	K413339
F2229402	Certificate of Analysis	Apr 03, 2025	K413339
F2229397	Certificate of Analysis	Apr 03, 2025	K413339

Chemical and Physical Properties

Solubility	Solubility (25°C) In vitro DMSO: 36 mg/mL (200.36 mM); Water: 36 mg/mL (200.36 mM); Ethanol: 21 mg/mL (116.88 mM);
DMSO(mg / mL) Max Solubility	36
DMSO(mM) Max Solubility	200.36734012356
Water(mg / mL) Max Solubility	36
Water(mM) Max Solubility	200.36734012356
Molecular Weight	179.670 g/mol
XLogP3
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	4
Exact Mass	179.028 Da
Monoisotopic Mass	179.028 Da
Topological Polar Surface Area	99.000 Å²
Heavy Atom Count	10
Formal Charge	0
Complexity	134.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	2

Solution Calculators

Molarity Calculator

Determine the necessary mass, volume, or concentration for preparing a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions, always use the batch-specific molecular weight of the product found on the vial label and the Certificate of Analysis (available online).

Dilution Calculator

Determine the dilution needed to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator enables you to quickly determine the volume of a reagent needed to reconstitute your vial. Just enter the mass of the reagent and the target concentration, and the calculator will do the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

Reviews

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.