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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab182968-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$59.90
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Ab182968-1mg
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1mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$259.90
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Ab182968-5mg
|
5mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$669.90
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Ab182968-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,079.90
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Purity≥95% (SDS-PAGE&SEC); Endotoxin Level≤1.0EU/mg; Canis IgG2; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Izenivetmab (anti-NGF) - Primary antibody, specific to NGF, Dog IgG2 |
|---|---|
| Synonyms | Beta nerve growth factor antibody | Beta NGF antibody | Beta-nerve growth factor antibody | Beta-NGF antibody | HSAN5 antibody | MGC161426 antibody | MGC161428 antibody | Nerve growth factor (beta polypeptide) antibody | Nerve growth factor antibody | Ner |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Biochemical and Physiological Mechanisms | Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to reg |
| Host species | Dog |
| Specificity | NGF |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Product Description |
Izenivetmab (anti-NGF) is a caninized IgG2κ anti-NGFB monoclonal antibody.
|
| Isotype | Dog IgG2 |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 147.44 kDa |
| Purification Method | Protein A purified |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 2447755-72-6 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Izenivetmab (anti-NGF) (Ab182968) - ELISA
Immobilized Recombinant Human β-NGF protein at 2.0 μg/mL can bind Izenivetmab (anti-NGF) (Ab182968) with the EC₅₀ of 12.39 ng/mL.
Izenivetmab (anti-NGF) (Ab182968) - SEC
The purity of Izenivetmab (anti-NGF) (Ab182968) is more than 95% verified by HPLC.