Isopulegol is monoterpene alcohol, a useful ingredient for the production of fragrances in perfume industries. It is also used as a starting material in the manufacture of menthol by the hydrogenation process. Menthol is an important component in cosmetics, pharmaceuticals, and toothpaste.
Application
(−)-Isopulegol can be used as a starting material for the enantioselective preparation of: 8-arylmenthols by Smiles-Truce rearrangement of aryl sulfonates.,· Stereoisomers of 5,9-dimethylpentadecane. Octahydro-2 H -chromen-4-ol by Prins cyclization with vanillin in the presence of montmorillonite clay as the catalyst. p -menthane-3,8,9-triol by catalytic Sharpless dihydroxylation.
This compound belongs to the class of organic compounds known as menthane monoterpenoids. These are monoterpenoids with a structure based on the o-, m-, or p-menthane backbone. P-menthane consists of the cyclohexane ring with a methyl group and a (2-methyl)-propyl group at the 1 and 4 ring position, respectively. The o- and m- menthanes are much rarer, and presumably arise by alkyl migration of p-menthanes.
External Descriptors
p-menthane monoterpenoid
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
