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Basic Description
| Synonyms | ISOPROPYL MYRISTATE | 110-27-0 | Isopropyl tetradecanoate | Estergel | Isomyst | Bisomel | Promyr | Tetradecanoic acid, 1-methylethyl ester | Deltyl Extra | Kesscomir | Tegester | Sinnoester MIP | Crodamol IPM | Plymoutm IPM | Starfol IPM | Unimate IPM | Kessco IPM | Stepan D-50 | Emcol-IM | |
|---|---|
| Specifications & Purity | 10mM in DMSO |
| Storage Temp | Store at -80°C |
| Shipped In |
Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available. |
| Product Description |
IPM is a fatty acid ester that can be produced by the esterification of isopropyl alcohol and myristic acid.
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Taxonomic Classification
Taxonomy Tree
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Kingdom
Organic compounds
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Superclass
Lipids and lipid-like molecules
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Class
Fatty Acyls
- Subclass Fatty acid esters
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Class
Fatty Acyls
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Superclass
Lipids and lipid-like molecules
| Kingdom | Organic compounds |
|---|---|
| Superclass | Lipids and lipid-like molecules |
| Class | Fatty Acyls |
| Subclass | Fatty acid esters |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Fatty acid esters |
| Alternative Parents | Carboxylic acid esters Monocarboxylic acids and derivatives Organic oxides Hydrocarbon derivatives Carbonyl compounds |
| Molecular Framework | Aliphatic acyclic compounds |
| Substituents | Fatty acid ester - Carboxylic acid ester - Monocarboxylic acid or derivatives - Carboxylic acid derivative - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Carbonyl group - Aliphatic acyclic compound |
| Description | This compound belongs to the class of organic compounds known as fatty acid esters. These are carboxylic ester derivatives of a fatty acid. |
| External Descriptors | Wax monoesters |
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Associated Targets(Human)
AR
Tclin
Androgen Receptor (11781 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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THRB
Tclin
Thyroid hormone receptor beta-1 (7926 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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LMNA
Tbio
Prelamin-A/C (36751 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Associated Targets(non-human)
Hdac6
Histone deacetylase 6 (222 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Micrococcus luteus (7463 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Staphylococcus aureus (210822 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Escherichia coli (133304 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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GCN5
Histone acetyltransferase GCN5 (89 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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rep
Replicase polyprotein 1ab (378 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Mechanisms of Action
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Names and Identifiers
| IUPAC Name | propan-2-yl tetradecanoate |
|---|---|
| INCHI | InChI=1S/C17H34O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-17(18)19-16(2)3/h16H,4-15H2,1-3H3 |
| InChIKey | AXISYYRBXTVTFY-UHFFFAOYSA-N |
| Smiles | CCCCCCCCCCCCCC(=O)OC(C)C |
| Isomeric SMILES | CCCCCCCCCCCCCC(=O)OC(C)C |
| RTECS | XB8600000 |
| Molecular Weight | 270.45 |
| Beilstein | 1781127 |
| Reaxy-Rn | 1781127 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1781127&ln= |
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
| Freezing Point(°C) | 7 °C |
|---|---|
| Refractive Index | 1.434-1.436 |
| Flash Point(°F) | 305.6 °F |
| Flash Point(°C) | 152 °C |
| Boil Point(°C) | 193 °C/20 mmHg (lit.) |
| Melt Point(°C) | 3 °C |
| Molecular Weight | 270.500 g/mol |
| XLogP3 | 7.200 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 14 |
| Exact Mass | 270.256 Da |
| Monoisotopic Mass | 270.256 Da |
| Topological Polar Surface Area | 26.300 Ų |
| Heavy Atom Count | 19 |
| Formal Charge | 0 |
| Complexity | 199.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
Citations of This Product
| 1. Dafei Li, Haoran Yin, Yingni Wu, Wei Feng, Ke-fei Xu, Huining Xiao, Chengcheng Li. (2023) Ultrastable High Internal Phase Pickering Emulsions: Forming Mechanism, Processability, and Application in 3D Printing. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 71 (48): (18829–18841). |
| 2. Jianxia Dong, Shu Wang, Jiamin Mao, Zhidan Wang, Shiying Zhao, Qiao Ren, Jialing Kang, Jing Ye, Xiaohong Xu, Yujin Zhu, Quan Zhang. (2023) Preparation of Dihydromyricetin-Loaded Self-Emulsifying Drug Delivery System and Its Anti-Alcoholism Effect. Pharmaceutics, 15 (9): (2296). |
| 3. Dafei Li, Yingni Wu, Haoran Yin, Wei Feng, Xiaoshuang Ma, Huining Xiao, Wenfeng Xin, Chengcheng Li. (2023) Panax Notoginseng polysaccharide stabilized gel-like Pickering emulsions: Stability and mechanism. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 249 (125893). |
| 4. Feng Shi, Wenxiong Yin, Michael Adu-Frimpong, Xiaoxiao Li, Xiaoli Xia, Weigang Sun, Hao Ji, Elmurat Toreniyazov, Wang Qilong, Xia Cao, Jiangnan Yu, Ximing Xu. (2023) In-vitro and in-vivo evaluation and anti-colitis activity of esculetin-loaded nanostructured lipid carrier decorated with DSPE-MPEG2000. JOURNAL OF MICROENCAPSULATION, |
| 5. Jianbing Wu, Wenjun Guo, Yongfeng Wang, Jian Liu, Heng Wang, Zhaozhu Zheng, Xiaoqin Wang, David L. Kaplan. (2023) Stabilization and Sustained Release of Fragrances Using Silk-PEG Microspheres. ACS Biomaterials Science & Engineering, 9 (6): (3335–3347). |
| 6. Cao Xia, Liu Qi, Adu-Frimpong Michael, Shi Wenwan, liu Kai, Deng Tianwen, Yuan Hui, Weng Xuedi, Gao Yihong, Yu Qingtong, Deng Wenwen, Yu Jiangnan, Wang Qilong, Xiao Gao, Xu Ximing. (2023) Microfluidic Generation of Near-Infrared Photothermal Vitexin/ICG Liposome with Amplified Photodynamic Therapy. AAPS PHARMSCITECH, 24 (4): (1-18). |
| 7. Yue Zhang, Wenxiu Pan, Dequan Wang, Han Wang, Yanting Hou, Meijuan Zou, Hongyu Piao. (2023) Solid-in-oil nanodispersion as a novel topical transdermal delivery to enhance stability and skin permeation and retention of hydrophilic drugs l-ascorbic acid. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 185 (82). |
| 8. Dan Chen, Yurong Liu, Peiwen Liu, Yang Zhou, Longguang Jiang, Cai Yuan, Mingdong Huang. (2022) Orally delivered rutin in lipid-based nano-formulation exerts strong antithrombotic effects by protein disulfide isomerase inhibition. DRUG DELIVERY, |
| 9. Bingying Wang, Zaisheng Zhu, Jiayu Yin, Xiaoxing Lu. (2023) Microemulsion system formed with new piperazinium-based surface-active ionic liquid. JOURNAL OF MOLECULAR LIQUIDS, 371 (121103). |
| 10. Min Li, Ping Zhan, Peng Wang, Honglei Tian, Jingzhang Geng, Lixia Wang. (2023) Characterization of aroma-active compounds changes of Xiecun Huangjius with different aging years based on odor activity values and multivariate analysis. FOOD CHEMISTRY, 405 (134809). |
| 11. Linghui Zou, Wenya Ding, Qiuyan Huang, Xu Yang, Jilang Li, Tianyan Huang, Zeyu Li, Si Lin, Jianfang Feng. (2022) Andrographolide/Phospholipid/Cyclodextrin Complex-Loaded Nanoemulsion: Preparation, Optimization, in Vitro and in Vivo Evaluation. BIOLOGICAL & PHARMACEUTICAL BULLETIN, 45 (8): (1106-1115). |
| 12. Gang Wang, Yu Yang, Du Yi, Lu Yuan, Pei-Hao Yin, Xu Ke, Wang Jun-Jie, Min-Fang Tao. (2022) Eudragit S100 prepared pH-responsive liposomes-loaded betulinic acid against colorectal cancer in vitro and in vivo. JOURNAL OF LIPOSOME RESEARCH, 32 (3): (250-264). |
| 13. Chunmei Wei, Qilong Wang, Wen Weng, Michael Adu-Frimpong, Elmurat Toreniyazov, Hao Ji, Ximing Xu, Jiangnan Yu. (2021) Enhanced oral bioavailability and anti-hyperuricemic activity of liquiritin via a self-nanoemulsifying drug delivery system. JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 102 (5): (2032-2040). |
| 14. Dan Ye, Liyan Shen, Ying Sun, Di Zhang, Xiao Tan, Panpan Jing, Min Zhang, Qingping Tian. (2021) Formulation and evaluation of a α-linolenic acid and vitamin E succinate microemulsion with low surfactant content and free of co-surfactant for use as a nutritional supplement. FOOD CHEMISTRY, 364 (130433). |
| 15. Qilong Wang, Chunmei Wei, Wen Weng, Rui Bao, Michael Adu-Frimpong, Elmurat Toreniyazov, Hao Ji, Xi-Ming Xu, JiangNan Yu. (2021) Enhancement of oral bioavailability and hypoglycemic activity of liquiritin-loaded precursor liposome. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 592 (120036). |
| 16. Gang Wang, Yang Yu, Yu‑Zhu Wang, Zhi‑Min Zhu, Pei‑Hao Yin, Ke Xu. (2020) Effects and mechanisms of fatty acid metabolism‑mediated glycolysis regulated by betulinic acid‑loaded nanoliposomes in colorectal cancer. ONCOLOGY REPORTS, 44 (6): (2595-2609). |
| 17. Gang Wang, Yang Yu, Yu-Zhu Wang, Pei-Hao Yin, Ke Xu, Heng Zhang. (2020) The effects and mechanisms of isoliquiritigenin loaded nanoliposomes regulated AMPK/mTOR mediated glycolysis in colorectal cancer. Artificial Cells Nanomedicine and Biotechnology, 48 (1): (1231-1249). |
| 18. Yongqiang Zhang, Yingying Cao, Xiangzhan Meng, Chunshan Li, Hui Wang, Suojiang Zhang. (2020) Enhancement of transdermal delivery of artemisinin using microemulsion vehicle based on ionic liquid and lidocaine ibuprofen. COLLOIDS AND SURFACES B-BIOINTERFACES, 189 (110886). |
| 19. Wen Weng, Qilong Wang, Chunmei Wei, Na Man, Kangyi Zhang, Qiuyu Wei, Michael Adu-Frimpong, Elmurat Toreniyazov, Hao Ji, Jiangnan Yu, Ximing Xu. (2019) Preparation, characterization, pharmacokinetics and anti-hyperuricemia activity studies of myricitrin-loaded proliposomes. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 572 (118735). |
| 20. Liu Xiaofeng, Xia Yongjun, Zhang Yao, Yi Zhenwei, Meng Peng, Wang Guangqiang, Ai Lianzhong. (2019) Enhancement of antroquinonol and antrodin C productions via in situ extractive fermentation of Antrodia camphorata S-29. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 103 (20): (8351-8361). |
| 21. F. Chen, C. Dong, C. Chen, W.D. Yin, W. Zhai, X.Y. Ma, B. Wei. (2019) Nitrogen-aeration tuned ultrasonic synthesis of SiO2@PNIPAm nanoparticles and preparation of temperature responsive Pickering emulsion. ULTRASONICS SONOCHEMISTRY, 58 (104705). |
| 22. Xia-Lin Dai, Alexander P. Voronin, Wei Gao, German L. Perlovich, Tong-Bu Lu, Jia-Mei Chen. (2019) Intermolecular interactions and permeability of 5-fluorouracil cocrystals with a series of isomeric hydroxybenzoic acids: a combined theoretical and experimental study. CRYSTENGCOMM, 21 (34): (5095-5105). |
| 23. Zeng Liya, Liu Yongchang, Pan Jun, Liu Xiaowen. (2019) Formulation and evaluation of norcanthridin nanoemulsions against the Plutella xylostella (Lepidotera: Plutellidae). BMC BIOTECHNOLOGY, 19 (1): (1-11). |
| 24. Lin Sun, Zeyu Liu, Zibei Lin, Dongmei Cun, Henry HY Tong, Ru Yan, Ruibing Wang, Ying Zheng. (2018) Comparison of normal versus imiquimod-induced psoriatic skin in mice for penetration of drugs and nanoparticles. International Journal of Nanomedicine, |
| 25. Xinyue Wang, Xinyue Lu, Lili Wen, Zongning Yin. (2018) Incomplete phase inversion W/O/W emulsion and formation mechanism from an interfacial perspective. JOURNAL OF DISPERSION SCIENCE AND TECHNOLOGY, |
| 26. Qilong Wang, Qiuyu Wei, Qiuxuan Yang, Xia Cao, Qiang Li, Feng Shi, Shan Shan Tong, Chunlai Feng, Qingtong Yu, Jiangnan Yu, Ximing Xu. (2018) A novel formulation of [6]-gingerol: Proliposomes with enhanced oral bioavailability and antitumor effect. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 535 (308). |
| 27. Jiao Yu, Kawai Wan, Xun Sun. (2017) Improved transdermal delivery of morin efficiently inhibits allergic contact dermatitis. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 530 (145). |
| 28. Liya Zeng, Yalin Zhang. (2017) Development, optimization and in vitro evaluation of norcantharidin loadedself-nanoemulsifying drug delivery systems (NCTD-SNEDDS). PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY, |
| 29. Rui Xue Guo, Xiong Fu, Jian Chen, Lin Zhou, Gu Chen. (2016) Preparation and Characterization of Microemulsions of Myricetin for Improving Its Antiproliferative and Antioxidative Activities and Oral Bioavailability. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 64 (32): (6286–6294). |
| 30. Zhou Lihua, Niu Yu, Yang Jinbei, Li Chenggang, Guo Xiaoting, Li Ling, Qiu Ting. (2016) Reaction kinetics for synthesis of isopropyl myristate catalyzed by sulfated titania. KOREAN JOURNAL OF CHEMICAL ENGINEERING, 33 (8): (2478-2485). |
| 31. Tao Wan, Ting Xu, Jingtong Pan, Mengyao Qin, Wenhui Pan, Guoguang Zhang, Zushuai Wu, Chuanbin Wu, Yuehong Xu. (2015) Microemulsion based gel for topical dermal delivery of pseudolaric acid B: In vitro and in vivo evaluation. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 493 (111). |
| 32. Junxiu Che, Zushuai Wu, Weiyan Shao, Penghao Guo, Yuanyuan Lin, Wenhui Pan, Weidong Zeng, Guoguang Zhang, Chuanbin Wu, Yuehong Xu. (2015) Synergetic skin targeting effect of hydroxypropyl-β-cyclodextrin combined with microemulsion for ketoconazole. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 93 (136). |
| 33. Hongxing Ma,Mingjuan Chu,Kiyoshi Itagaki,Ping Xin,Xuegang Zhou,Dawei Zhang,Youzhi Wang,Jia Fu,Shiqin Sun. (2014-12-03) Formulation and in vitro characterization of a novel solid lipid-based drug delivery system.. Chemical & pharmaceutical bulletin, 62 ((12)): (1173-1179). |
| 34. Hong-Yu Xu,Chang-Shun Liu,Chuan-Li Huang,Li Chen,Yu-Rong Zheng,Si-Hang Huang,Xiao-Ying Long. (2019-08-07) Nanoemulsion improves hypoglycemic efficacy of berberine by overcoming its gastrointestinal challenge.. Colloids and surfaces. B, Biointerfaces, 181 (927-934). |
| 35. Yun Zhou, Xu He, Wen Zhang, Weiguo Zhang, Huan Zhao, Xichao Zhou, Qiaoli Gu, Hao Shen, Huilin Yang, Xingzhi Liu, Lixin Huang, Qin Shi. (2024) Cell-recruited microspheres for OA treatment by dual-modulating inflammatory and chondrocyte metabolism. Materials Today Bio, 27 (101127). |
| 36. Li Bin, Jiao Siwen, Guo Shiqi, Xiao Ting, Zeng Yao, Hu Yingwei, Li Xiaojuan, Xiong Sha, Xu Yuehong. (2024) Deep eutectic solvent self-assembled reverse nanomicelles for transdermal delivery of sparingly soluble drugs. JOURNAL OF NANOBIOTECHNOLOGY, 22 (1): (1-22). |
| 37. Xiao Xiao, Feiyu Yang, Yuling Huang, Shaohui Liu, Zhenhua Hu, Shanggao Liao, Yuanyuan Li. (2024) Enhanced In Vitro Efficacy of Verbascoside in Suppressing Hepatic Stellate Cell Activation via ROS Scavenging with Reverse Microemulsion. Antioxidants, 13 (8): (907). |
| 38. Jiachen He, Jianjun Wu, Jingcheng Zheng, Yidan Xu, Keyun Li, Siwei Yin, Yanyun Liu, Yuelin Hu, Chaoming Xie, Limin Cai, Yikuan Du, Xiong Lu. (2025) Injectable Chondroitin Sulfate Microspheres with Gallic Acid-Magnesium MOF for Anti-Inflammatory and Cartilage Degeneration Alleviation in Osteoarthritis Treatment. ACS Applied Materials & Interfaces, |
| 39. Zi-Lin Li, Guo-Xing Deng, Chuan-Zhou Fang, Yue-Qi Zhao, Jing Yuan, Liang Chen, Hai-Jun Zhong, Feng Guo. (2025) Solid Self-Microemulsifying Drug Delivery System for Improved Oral Bioavailability of Relugolix: Preparation and Evaluation. International Journal of Nanomedicine, |
| 40. Ziqian Xiang, Chuang Chen, Fang Chen, Wei Zhai. (2024) Surface grafting polymerization via cavitation regulated sonochemistry. EUROPEAN POLYMER JOURNAL, 207 (112839). |
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