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INY-03-041 trihydrochloride - 99%, high purity , CAS No.I659395

COA

Grade & Purity:

≥99%

Molecular Weight: 907.8

In stock

Item Number

I659395

Grouped product items
SKU	Size	Availability	Price	Qty
I659395-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$790.90
I659395-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,750.90

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Basic Description

Specifications & Purity	≥99%
Storage Temp	Protected from light,Store at -20°C,Desiccated
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	INY-03-041 trihydrochloride is a potent, highly selective and PROTAC-based pan- AKT degrader consisting of the ATP-competitive AKT inhibitor Ipatasertib ( HY-15186 ) conjugated to Lenalidomide (HY-A0003, Cereblon ligand). INY-03-041 trihydrochloride inhib Appearance:Solid IC50& Target:Akt1 2.0 nM (IC 50 ) Akt3 3.5 nM (IC 50 ) Akt2 6.8 nM (IC 50 ) Cereblon In Vitro:INY-03-041 (10-1000 nM; 0-24 hours) induces potent degradation of all three AKT isoforms in MDA-MB-468 cells. INY-03-041 exhibits potent in vitro inhibition of S6K1 (IC 50 =37.3 nM) and PKG1 (IC 50 = 33.2 nM). INY-03-041 displays enhanced anti-p Biological Activity:INY-03-041 trihydrochloride is a potent, highly selective and PROTAC-based pan- AKT degrader consisting of the ATP-competitive AKT inhibitor Ipatasertib ( HY-15186 ) conjugated to Lenalidomide (HY-A0003, Cereblon ligand). INY-03-041 trihydrochloride inhib

Names and Identifiers

Smiles	O=C(C(N(CC1=C2C=CC=C1CCCCCCCCCCNC[C@H](C3=CC=C(Cl)C=C3)C(N4CCN(C5=C([C@H](C)C[C@H]6O)C6=NC=N5)CC4)=O)C2=O)CC7)NC7=O.Cl.Cl.Cl
Molecular Weight	907.8

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

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