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Immunoglobulin G1 (IgG1), Human Myeloma Plasma, FC Fragment

COA

Grade & Purity:

≥95%(SDS-PAGE)
Extinction Coefficient: 1.35

In stock

Item Number

np001063

Grouped product items
SKU	Size	Availability	Price	Qty
np001063-250μg	250μg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$375.90
np001063-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,250.90

View related series

Human Proteins (109) Immunoglobulins (34)

Basic Description

Product Name	Immunoglobulin G1 (IgG1), Human Myeloma Plasma, FC Fragment
Product Description	Crystallizable fragments composed of the carboxy-terminal halves of both Immunoglobulins Heavy Chains linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (Complement fixation, binding to the cell membrane via FC Receptors, and placental transport). IgG1 FC was reported has a novel role as a potential anti-inflammatory drug for treatment of human autoimmune diseases. The IgG1 FC fragment does not bind antigen; however, it does contain the classic antigenic determinants and biological activity with respect to cytotrophic reactions, binding of complement and catabolic rate control. Prepared from plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA-required tests. Ref.: Anthony R, Ravetch J, et al. (2010), J Clin Immunol. 30 Suppl 1:S9-14
Specifications & Purity	≥95%(SDS-PAGE), Extinction Coefficient: 1.35
Predicted molecular weight	50,000Da

Storage and Shipping

Shape	Frozen in 50 mM Tris-HCl, pH 8.0, with 200 mM NaCl and 0.05% NaN3.
Concentration	Extinction Coefficient: 1.35
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

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