Determine the necessary mass, volume, or concentration for preparing a solution.
This is a demo store. No orders will be fulfilled.
| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
|
I274908-1mg
|
1mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$278.90
|
|
Cell-permeable definitive endoderm formation inducer
| Synonyms | 7-(2-Cyclopentylidenehydrazinyl)-7-oxoheptanoicacid |
|---|---|
| Specifications & Purity | ≥98% |
| Biochemical and Physiological Mechanisms | Cell-permeable definitive endoderm formation inducer (EC 50 = 223 nM, induction of Sox17 expression in ESCs) similar to IDE 1 . Activates TGF-β signaling and downstream Smad2 phosphorylation. Upregulates Nodal expression. |
| Storage Temp | Store at -20°C,Desiccated |
| Shipped In |
Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available. |
| Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
| Product Description |
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. |
Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Lipids and lipid-like molecules |
| Class | Fatty Acyls |
| Subclass | Fatty acids and conjugates |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Medium-chain fatty acids |
| Alternative Parents | Amino fatty acids Monocarboxylic acids and derivatives Carboxylic acids Organonitrogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds |
| Molecular Framework | Aliphatic homomonocyclic compounds |
| Substituents | Medium-chain fatty acid - Amino fatty acid - Monocarboxylic acid or derivatives - Carboxylic acid - Carboxylic acid derivative - Organic nitrogen compound - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Carbonyl group - Aliphatic homomonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as medium-chain fatty acids. These are fatty acids with an aliphatic tail that contains between 4 and 12 carbon atoms. |
| External Descriptors | Not available |
|
|
|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
| IUPAC Name | 7-(2-cyclopentylidenehydrazinyl)-7-oxoheptanoic acid |
|---|---|
| INCHI | InChI=1S/C12H20N2O3/c15-11(8-2-1-3-9-12(16)17)14-13-10-6-4-5-7-10/h1-9H2,(H,14,15)(H,16,17) |
| InChIKey | CVYPYYPTFNVREL-UHFFFAOYSA-N |
| Smiles | C1CCC(=NNC(=O)CCCCCC(=O)O)C1 |
| Isomeric SMILES | C1CCC(=NNC(=O)CCCCCC(=O)O)C1 |
| Molecular Weight | 240.3 |
| Reaxy-Rn | 38947859 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=38947859&ln= |
| Solubility | Soluble in water to 20 mM, in ethanol to 100 mM and in DMSO to 100 mM |
|---|---|
| Molecular Weight | 240.300 g/mol |
| XLogP3 | 0.900 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 7 |
| Exact Mass | 240.147 Da |
| Monoisotopic Mass | 240.147 Da |
| Topological Polar Surface Area | 78.800 Ų |
| Heavy Atom Count | 17 |
| Formal Charge | 0 |
| Complexity | 292.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |